Updates in the Classification of T-cell Lymphomas and Lymphoproliferative Disorders

•• Alaggio R, Amador C, Anagnostopoulos I, et al. The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms. Leukemia. 2022;36:1720–48. The most recent version of the World Health Organization (WHO) classification.

Article  PubMed  PubMed Central  Google Scholar 

•• Campo E, Jaffe ES, Cook JR, et al. The International Consensus Classification of mature lymphoid neoplasms: a report from the Clinical Advisory Committee. Blood. 2022;140:1229–53. The 2022 International Consensus Classification (ICC) by the Clinical Advisory Committee.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Oishi N, Feldman AL. Current concepts in nodal peripheral T-cell lymphomas. Surg Pathol Clin. 2023;16:267–85.

Article  PubMed  Google Scholar 

Feldman AL, Laurent C, Narbaitz M, et al. Classification and diagnostic evaluation of nodal T- and NK-cell lymphomas. Virchows Arch. 2023;482:265–79.

Article  CAS  PubMed  Google Scholar 

de Leval L, Feldman AL, Pileri S, et al. Extranodal T- and NK-cell lymphomas. Virchows Arch. 2023;482:245–64.

Article  PubMed  Google Scholar 

Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127:2375–90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

de Leval L, Alizadeh AA, Bergsagel PL, et al. Genomic profiling for clinical decision making in lymphoid neoplasms. Blood. 2022;140:2193–227.

Article  PubMed  Google Scholar 

Staber PB, Herling M, Bellido M, et al. Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia. Blood. 2019;134:1132–43.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Patil P, Cieslak A, Bernhart SH, et al. Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia. Genes Chromosom Cancer. 2020;59:261–7.

Article  CAS  PubMed  Google Scholar 

Koskela HLM, Eldfors S, Ellonen P, et al. Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia. N Engl J Med. 2012;366:1905–13.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi M, He R, Feldman AL, et al. STAT3 mutation and its clinical and histopathologic correlation in T-cell large granular lymphocytic leukemia. Hum Pathol. 2018;73:74–81.

Article  CAS  PubMed  Google Scholar 

Rajala HLM, Eldfors S, Kuusanmäki H, et al. Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia. Blood. 2013;121:4541–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andersson EI, Tanahashi T, Sekiguchi N, et al. High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia. Blood. 2016;128:2465–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nosaka K, Matsuoka M. Adult T-cell leukemia-lymphoma as a viral disease: Subtypes based on viral aspects. Cancer Sci. 2021;112:1688–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Karube K, Takatori M, Sakihama S, et al. Clinicopathological features of adult T-cell leukemia/lymphoma with HTLV-1-infected Hodgkin and Reed-Sternberg-like cells. Blood Adv. 2021;5:198–206.

CAS  PubMed  PubMed Central  Google Scholar 

Tamaki T, Karube K, Sakihama S, et al. a comprehensive study of the immunophenotype and its clinicopathologic significance in adult T-cell leukemia/lymphoma. Mod Pathol. 2023;36: 100169.

Article  PubMed  Google Scholar 

Karube K, Aoki R, Sugita Y, et al. The relationship of FOXP3 expression and clinicopathological characteristics in adult T-cell leukemia/lymphoma. Mod Pathol. 2008;21:617–25.

Article  CAS  PubMed  Google Scholar 

Takatori M, Sakihama S, Miyara M, et al. A new diagnostic algorithm using biopsy specimens in adult T-cell leukemia/lymphoma: combination of RNA in situ hybridization and quantitative PCR for HTLV-1. Mod Pathol. 2021;34:51–8.

Article  CAS  PubMed  Google Scholar 

Yamada K, Miyoshi H, Yoshida N, et al. Human T-cell lymphotropic virus HBZ and tax mRNA expression are associated with specific clinicopathological features in adult T-cell leukemia/lymphoma. Mod Pathol. 2021;34:314–26.

Article  CAS  PubMed  Google Scholar 

Kogure Y, Kataoka K. Genetic alterations in adult T-cell leukemia/lymphoma. Cancer Sci. 2017;108:1719–25.

Article  CAS  PubMed  PubMed Central  Google Scholar 

• Kogure Y, Kameda T, Koya J, et al. Whole-genome landscape of adult T-cell leukemia/lymphoma. Blood. 2022;139:967–82. A comprehensive molecular study of adult T-cell luekemia/lymphoma (ATLL).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kataoka K, Nagata Y, Kitanaka A, et al. Integrated molecular analysis of adult T cell leukemia/lymphoma. Nat Genet. 2015;47:1304–15.

Article  CAS  PubMed  Google Scholar 

Kataoka K, Shiraishi Y, Takeda Y, et al. Aberrant PD-L1 expression through 3’-UTR disruption in multiple cancers. Nature. 2016;534:402–6.

Article  CAS  PubMed  Google Scholar 

Moffitt AB, Ondrejka SL, McKinney M, et al. Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2. J Exp Med. 2017;214:1371–86.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sharma A, Oishi N, Boddicker RL, et al. Recurrent STAT3-JAK2 fusions in indolent T-cell lymphoproliferative disorder of the gastrointestinal tract. Blood. 2018;131:2262–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Perry AM, Warnke AR, Hu Q, et al. Indolent T-cell lymphoproliferative disease of the gastrointestinal tract. Blood. 2013;122:3599–606.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Margolskee E, Jobanputra V, Lewis SK, et al. Indolent Small Intestinal CD4+ T-cell Lymphoma Is a Distinct Entity with Unique Biologic and Clinical Features. Tran DQ, ed. PLoS One. 2013;8:e68343.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Soderquist CR, Patel N, Murty VV, et al. Genetic and phenotypic characterization of indolent T-cell lymphoproliferative disorders of the gastrointestinal tract. Haematologica. 2020;105:1895–906.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Takeuchi K, Yokoyama M, Ishizawa S, et al. Lymphomatoid gastropathy: A distinct clinicopathologic entity of self-limited pseudomalignant NK-cell proliferation. Blood. 2010;116:5631–7.

Article  CAS  PubMed  Google Scholar 

Mansoor A, Pittaluga S, Beck PL, et al. NK-cell enteropathy: a benign NK-cell lymphoproliferative disease mimicking intestinal lymphoma: clinicopathologic features and follow-up in a unique case series. Blood. 2011;117:1447–52.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xiao W, Gupta GK, Yao J, et al. Recurrent somatic JAK3 mutations in NK-cell enteropathy. Blood. 2019;134:986–91.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yabe M, Miranda RN, Medeiros LJ. Hepatosplenic T-cell Lymphoma: a review of clinicopathologic features, pathogenesis, and prognostic factors. Hum Pathol. 2018;74:5–16.

Article  CAS  PubMed  Google Scholar 

Nicolae A, Xi L, Pittaluga S, et al. Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas. Leukemia. 2014;28:2244–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

McKinney M, Moffitt AB, Gaulard P, et al. The genetic basis of hepatosplenic T-cell lymphoma. Cancer Discov. 2017;7:369–79.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feldman AL, Oishi N, Ketterling RP, et al. Immunohistochemical approach to genetic subtyping of anaplastic large cell lymphoma. Am J Surg Pathol. 2022;46:1490–9.

Article  PubMed  Google Scholar 

Ravindran A, Feldman AL, Ketterling RP, et al. Striking association of lymphoid enhancing factor (LEF1) overexpression and DUSP22 rearrangements in anaplastic large cell lymphoma. Am J Surg Pathol. 2021;45:550–7.

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