Ahmad R, Wojciech S, Jockers R (2018) GPR50 in TGFbeta signaling and breast cancer. Oncoscience 5(5–6):157–158. https://doi.org/10.18632/oncoscience.433
Article PubMed PubMed Central Google Scholar
Ai J, Huang H, Lv X, Tang Z, Chen M, Chen T, Duan W, Sun H, Li Q, Tan R, Liu Y, Duan J, Yang Y, Wei Y, Li Y, Zhou Q (2011) FLNA and PGK1 are two potential markers for progression in hepatocellular carcinoma. Cell Physiol Biochem 27(3–4):207–216. https://doi.org/10.1159/000327946
Article CAS PubMed Google Scholar
An X, Wang T, Zhang W, Yu H, Chunhua Zhao R, Guo Y, Wang C, Qin L, Guo C (2020) Chondroprotective Effects of Combination Therapy of Acupotomy and Human adipose mesenchymal stem cells in knee osteoarthritis rabbits via the GSK3beta-Cyclin D1-CDK4/CDK6 signaling pathway. Aging Dis 11(5):1116–1132. https://doi.org/10.14336/AD.2019.1104
Article PubMed PubMed Central Google Scholar
Cai Q, Wang S, Jin L, Weng M, Zhou D, Wang J, Tang Z, Quan Z (2019) Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy. Mol Cancer 18(1):82. https://doi.org/10.1186/s12943-019-1016-0
Article PubMed PubMed Central Google Scholar
Chang C, Zhao W, Luo Y, Xi L, Chen S, Zhao C, Wang G, Guo J, Xu C (2017) Serine peptidase inhibitor kazal type I (SPINK1) promotes BRL-3A cell proliferation via p38, ERK, and JNK pathways. Cell Biochem Funct 35(6):339–348. https://doi.org/10.1002/cbf.3288
Article CAS PubMed Google Scholar
Chang C, Wang D, Xi L, Guo X, Wang G, Yu G (2022) The orphan GPR50 receptor interacting with TbetaRI induces G1/S-phase cell cycle arrest via Smad3-p27/p21 in BRL-3A cells. Biochem Pharmacol 202:115117. https://doi.org/10.1016/j.bcp.2022.115117
Article CAS PubMed Google Scholar
Chao X, Qian H, Wang S, Fulte S, Ding WX (2020) Autophagy and liver cancer. Clin Mol Hepatol 26(4):606–617. https://doi.org/10.3350/cmh.2020.0169
Article PubMed PubMed Central Google Scholar
Chen YY, Liu FC, Wu TS, Sheu MJ (2015) Antrodia cinnamomea inhibits Migration in Human Hepatocellular Carcinoma cells: the role of ERp57 and PGK-1. Am J Chin Med 43(8):1671–1696. https://doi.org/10.1142/S0192415X15500950
Article CAS PubMed Google Scholar
Chen W, Ji H, Li L, Xu C, Zou T, Cui W, Xu S, Zhou X, Duan S, Wang Q (2019) Significant association between GPR50 hypomethylation and AD in males. Mol Med Rep 20(2):1085–1092. https://doi.org/10.3892/mmr.2019.10366
Article CAS PubMed PubMed Central Google Scholar
Crooke A, Guzman-Aranguez A, Mediero A, Alarma-Estrany P, Carracedo G, Pelaez T, Peral A, Pintor J (2015) Effect of melatonin and analogues on corneal wound healing: involvement of Mt2 melatonin receptor. Curr Eye Res 40(1):56–65. https://doi.org/10.3109/02713683.2014.914540
Article CAS PubMed Google Scholar
Delavest M, Even C, Benjemaa N, Poirier MF, Jockers R, Krebs MO (2012) Association of the intronic rs2072621 polymorphism of the X-linked GPR50 gene with affective disorder with seasonal pattern. Eur Psychiatry 27(5):369–371. https://doi.org/10.1016/j.eurpsy.2011.02.011
Article CAS PubMed Google Scholar
Ding Y, Chang C, Niu Z, Dai K, Geng X, Li D, Guo J, Xu C (2016) Overexpression of transcription factor Foxa2 and Hnf1alpha induced rat bone mesenchymal stem cells into hepatocytes. Cytotechnology 68(5):2037–2047. https://doi.org/10.1007/s10616-016-9944-7
Article CAS PubMed PubMed Central Google Scholar
Girard M, Dagenais Bellefeuille S, Eiselt E, Brouillette R, Placet M, Arguin G, Longpre JM, Sarret P, Gendron FP (2020) The P2Y6 receptor signals through galphaq /Ca(2+) /PKCalpha and Galpha13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration. J Cell Physiol 235(12):9676–9690. https://doi.org/10.1002/jcp.29779
Article CAS PubMed Google Scholar
Hu H, Zhu W, Qin J, Chen M, Gong L, Li L, Liu X, Tao Y, Yin H, Zhou H, Zhou L, Ye D, Ye Q, Gao D (2017) Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis. Hepatology 65(2):515–528. https://doi.org/10.1002/hep.28887
Article CAS PubMed Google Scholar
Hu X, Yuan G, Li Q, Huang J, Cheng X, Chen J (2021) DEAH-box polypeptide 32 promotes hepatocellular carcinoma progression via activating the beta-catenin pathway. Ann Med 53(1):437–447. https://doi.org/10.1080/07853890.2021.1898674
Article CAS PubMed PubMed Central Google Scholar
Huang K, Zeng Y, Xie Y, Huang L, Wu Y (2019) Bioinformatics analysis of the prognostic value of CCT6A and associated signalling pathways in breast cancer. Mol Med Rep 19(5):4344–4352. https://doi.org/10.3892/mmr.2019.10100
Article CAS PubMed PubMed Central Google Scholar
Li JH, Tao YF, Shen CH, Li RD, Wang Z, Xing H, Ma ES, Xue HY, Zhang QB, Ma ZY, Wang ZX (2022) Integrated multi-omics analysis identifies ENY2 as a predictor of recurrence and a regulator of telomere maintenance in hepatocellular carcinoma. Front Oncol 12:939948. https://doi.org/10.3389/fonc.2022.939948
Article PubMed PubMed Central Google Scholar
Liu F, Zhu C, Huang X, Cai J, Wang H, Wang X, He S, Liu C, Yang X, Zhang Y, Zhang T (2014) A low level of GPR37 is associated with human hepatocellular carcinoma progression and poor patient survival. Pathol Res Pract 210(12):885–892. https://doi.org/10.1016/j.prp.2014.07.011
Article CAS PubMed Google Scholar
Ma YX, Wu ZQ, Feng YJ, Xiao ZC, Qin XL, Ma QH (2015) G protein coupled receptor 50 promotes self-renewal and neuronal differentiation of embryonic neural progenitor cells through regulation of notch and wnt/beta-catenin signalings. Biochem Biophys Res Commun 458(4):836–842. https://doi.org/10.1016/j.bbrc.2015.02.040
Article CAS PubMed Google Scholar
O’Hayre M, Degese MS, Gutkind JS (2014) Novel insights into G protein and G protein-coupled receptor signaling in cancer. Curr Opin Cell Biol 27:126–135. https://doi.org/10.1016/j.ceb.2014.01.005
Article CAS PubMed PubMed Central Google Scholar
Oh J, Ceong HT, Na D, Park C (2022) A machine learning model for classifying G-protein-coupled receptors as agonists or antagonists. BMC Bioinformatics 23(Suppl 9):346. https://doi.org/10.1186/s12859-022-04877-7
Article CAS PubMed PubMed Central Google Scholar
Oishi A, Cecon E, Jockers R (2018) Melatonin receptor signaling: impact of receptor oligomerization on receptor function. Int Rev Cell Mol Biol 338:59–77. https://doi.org/10.1016/bs.ircmb.2018.02.002
Article CAS PubMed Google Scholar
Rajendran L, Ivanics T, Claasen MP, Muaddi H, Sapisochin G (2022) The management of post-transplantation recurrence of hepatocellular carcinoma. Clin Mol Hepatol 28(1):1–16. https://doi.org/10.3350/cmh.2021.0217
Ren D, Liu F, Dong G, You M, Ji J, Huang Y, Hou Y, Fan H (2016) Activation of TLR7 increases CCND3 expression via the downregulation of miR-15b in B cells of systemic lupus erythematosus. Cell Mol Immunol 13(6):764–775. https://doi.org/10.1038/cmi.2015.48
Article CAS PubMed Google Scholar
Shan Y, Lu C, Wang J, Li M, Ye S, Wu S, Huang J, Bu S, Wang F (2022) IGF-1 contributes to liver cancer development in diabetes patients by promoting autophagy. Ann Hepatol 27(4):100697. https://doi.org/10.1016/j.aohep.2022.100697
Article CAS PubMed Google Scholar
Shao X, Liu Y, Huang H, Zhuang L, Luo T, Huang H, Ge X (2015) Down-regulation of G protein-coupled receptor 137 by RNA interference inhibits cell growth of two hepatoma cell lines. Cell Biol Int 39(4):418–426. https://doi.org/10.1002/cbin.10412
Article CAS PubMed Google Scholar
Wang X, Li Y, Shi Y, Luo J, Zhang Y, Pan Z, Wu F, Tian J, Yu W (2022) Comprehensive analysis to identify the neurotransmitter receptor-related genes as prognostic and therapeutic biomarkers in hepatocellular carcinoma. Front Cell Dev Biol 10:887076. https://doi.org/10.3389/fcell.2022.887076
Article PubMed PubMed Central Google Scholar
Wojciech S, Ahmad R, Belaid-Choucair Z, Journe AS, Gallet S, Dam J, Daulat A, Ndiaye-Lobry D, Lahuna O, Karamitri A, Guillaume JL, Do Cruzeiro M, Guillonneau F, Saade A, Clement N, Courivaud T, Kaabi N, Tadagaki K, Delagrange P, Prevot V, Hermine O, Prunier C, Jockers R (2018) The orphan GPR50 receptor promotes constitutive TGFbeta receptor signaling and protects against cancer development. Nat Commun 9(1):1216. https://doi.org/10.1038/s41467-018-03609-x
Article CAS PubMed PubMed Central Google Scholar
Xie H, Tong G, Zhang Y, Liang S, Tang K, Yang Q (2017) PGK1 drives Hepatocellular Carcinoma Metastasis by enhancing metabolic process. Int J Mol Sci 18(8):1630. https://doi.org/10.3390/ijms18081630
Article CAS PubMed PubMed Central Google Scholar
Xu L, Shen J, Dai S, Sun L, Chen X (2020) Tetramethylpyrazine attenuated Sevoflurane-Induced neurotoxicity by enhancing autophagy through GPR50/CREB pathway in SH-SY5Y cells. Am J Chin Med 48(4):945–966. https://doi.org/10.1142/S0192415X20500457
Article CAS PubMed Google Scholar
Yang X, Tong Y, Ye W, Chen L (2022) HOXB2 increases the proliferation and invasiveness of colon cancer cells through the upregulation of CCT6A. Mol Med Rep 25(5):174. https://doi.org/10.3892/mmr.2022.12690
Article CAS PubMed PubMed Central Google Scholar
Yin Y, Xu X, Tang J, Zhang W, Zhangyuan G, Ji J, Deng L, Lu S, Zhuo H, Sun B (2018) CD97 promotes Tumor Aggressiveness through the traditional G protein-coupled receptor-mediated signaling in Hepatocellular Carcinoma. Hepatology 68(5):1865–1878. https://doi.org/10.1002/hep.30068
Comments (0)