Abreu JG, Ketpura NI, Reversade B, De Robertis EM (2002) Connective-tissue growth factor (ctgf) modulates cell signalling by bmp and TGF-β. Nat Cell Biol 4:599–604
Article CAS PubMed PubMed Central Google Scholar
Anastasia A, Deinhardt K, Chao MV, Will NE, Irmady K, Lee FS, Hempstead BL, Bracken C (2013) Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction. Nat Commun 4:2490
Antebi YE, Linton JM, Klumpe H, Bintu B, Gong M, Su C, McCardell R, Elowitz MB (2017) Combinatorial signal perception in the BMP pathway. Cell 170:1184-1196.e1124
Article CAS PubMed PubMed Central Google Scholar
Asch AS, Barnwell J, Silverstein RL, Nachman RL (1987) Isolation of the thrombospondin membrane receptor. J Clin Invest 79:1054–1061
Article CAS PubMed PubMed Central Google Scholar
Asch AS, Silbiger S, Heimer E, Nachman RL (1992) Thrombospondin sequence motif (CSVTCG) is responsible for CD36 binding. Biochem Biophys Res Commun 182:1208–1217
Article CAS PubMed Google Scholar
Baker D, Sohl JL, Agard DA (1992) A protein-folding reaction under kinetic control. Nature 356:263–265
Article CAS PubMed Google Scholar
Ball DK, Rachfal AW, Kemper SA, Brigstock DR (2003) The heparin-binding 10 kDa fragment of connective tissue growth factor (CTGF) containing module 4 alone stimulates cell adhesion. J Endocrinol 176:R1–R7
Article CAS PubMed Google Scholar
Barczyk M, Carracedo S, Gullberg D (2009) Integrins. Cell Tissue Res 339:269
Article PubMed PubMed Central Google Scholar
Berardinelli SJ, Eletsky A, Valero-González J, Ito A, Manjunath R, Hurtado-Guerrero R, Prestegard JH, Woods RJ, Haltiwanger RS (2022) O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond. J Biol Chem 298:102047
Article CAS PubMed PubMed Central Google Scholar
Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z et al (2000) Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2:737–744
Article CAS PubMed PubMed Central Google Scholar
Bonnans C, Chou J, Werb Z (2014) Remodelling the extracellular matrix in development and disease. Nat Rev Mol Cell Biol 15:786–801
Article CAS PubMed PubMed Central Google Scholar
Bork P (1993) The modular architecture of a new family of growth regulators related to connective tissue growth factor. FEBS Lett 327:125–130
Article CAS PubMed Google Scholar
Bornstein P (1995) Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1. J Cell Biol 130:503–506
Article CAS PubMed Google Scholar
Brigstock DR, Steffen CL, Kim GY, Vegunta RK, Diehl JR, Harding PA (1997) Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated M(r) 10,000 forms of connective tissue growth factor. J Biol Chem 272:20275–20282
Article CAS PubMed Google Scholar
Brozzo MS, Bjelić S, Kisko K, Schleier T, Leppänen V-M, Alitalo K, Winkler FK, Ballmer-Hofer K (2012) Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood 119:1781–1788
Article CAS PubMed Google Scholar
Butler GS, Connor AR, Sounni NE, Eckhard U, Morrison CJ, Noël A, Overall CM (2017) Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2). Matrix Biol 59:23–38
Article CAS PubMed Google Scholar
Canalis E, Smerdel-Ramoya A, Durant D, Economides AN, Beamer WG, Zanotti S (2010) Nephroblastoma overexpressed (Nov) inactivation sensitizes osteoblasts to bone morphogenetic protein-2, but Nov is dispensable for skeletal homeostasis. Endocrinology 151:221–233
Article CAS PubMed Google Scholar
Chakravarty D, Pedraza AM, Cotari J, Liu AH, Punko D, Kokroo A, Huse JT, Altan-Bonnet G, Brennan CW (2017) EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines. Sci Rep 7:9043
Article PubMed PubMed Central Google Scholar
Chen C-C, Lau LF (2009) Functions and mechanisms of action of CCN matricellular proteins. Int J Biochem Cell Biol 41:771–783
Article CAS PubMed Google Scholar
Chen N, Chen CC, Lau LF (2000) Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin α6β1 and cell surface heparan sulfate proteoglycans. J Biol Chem 275:24953–24961
Article CAS PubMed Google Scholar
Chen N, Leu SJ, Todorović V, Lam SCT, Lau LF (2004) Identification of a novel integrin αvβ3 binding site in CCN1 (CYR61) critical for pro-angiogenic activities in vascular endothelial cells. J Biol Chem 279:44166–44176
Article CAS PubMed Google Scholar
Curnis F, Cattaneo A, Longhi R, Sacchi A, Gasparri AM, Pastorino F, Di Matteo P, Traversari C, Bachi A, Ponzoni M et al (2010) Critical Role of flanking residues in NGR-to-isoDGR transition and CD13/Integrin receptor switching*. J Biol Chem 285:9114–9123
Article CAS PubMed PubMed Central Google Scholar
Dawson DW, Pearce SF, Zhong R, Silverstein RL, Frazier WA, Bouck NP (1997) CD36 mediates the In vitro inhibitory effects of thrombospondin-1 on endothelial cells. J Cell Biol 138:707–717
Article CAS PubMed PubMed Central Google Scholar
Dean RA, Butler GS, Hamma-Kourbali Y, Delbé J, Brigstock DR, Courty J, Overall CM (2007) Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (Pleiotrophin) and VEGF/connective tissue growth factor angiogenic inhibitory complexes by MMP-2 proteolysis. Mol Cell Biol 27:8454–8465
Article CAS PubMed PubMed Central Google Scholar
Eder J, Fersht AR (1995) Pro-sequence-assisted protein folding. Mol Microbiol 16:609–614
Article CAS PubMed Google Scholar
El-Gebali S, Mistry J, Bateman A, Eddy SR, Luciani A, Potter SC, Qureshi M, Richardson LJ, Salazar GA, Smart A et al (2019) The Pfam protein families database in 2019. Nucleic Acids Res 47:D427-d432
Article CAS PubMed Google Scholar
Fay PJ, Kawai Y, Wagner DD, Ginsburg D, Bonthron D, Ohlsson-Wilhelm BM, Chavin SI, Abraham GN, Handin RI, Orkin SH et al (1986) Propolypeptide of von Willebrand factor circulates in blood and is identical to von Willebrand antigen II. Science 232:995–998
Article CAS PubMed Google Scholar
Ferguson HR, Smith MP, Francavilla C (2021) Fibroblast growth factor receptors (FGFRs) and noncanonical partners in cancer signaling. Cells 10(5):1201
Article CAS PubMed PubMed Central Google Scholar
Firth SM, Baxter RC (2002) Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 23:824–854
Article CAS PubMed Google Scholar
Fu CT, Bechberger JF, Ozog MA, Perbal B, Naus CC (2004) CCN3 (NOV) interacts with connexin43 in C6 glioma cells: possible mechanism of connexin-mediated growth suppression. J Biol Chem 279:36943–36950
Article CAS PubMed Google Scholar
Gao R, Brigstock DR (2006) A novel integrin α5β1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cells. Gut 55:856–862
Article CAS PubMed PubMed Central Google Scholar
Gellhaus A, Dong X, Propson S, Maass K, Klein-Hitpass L, Kibschull M, Traub O, Willecke K, Perbal B, Lye SJ et al (2004) Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells. J Biol Chem 279:36931–36942
Article CAS PubMed Google Scholar
Gerritsen KG, Bovenschen N, Nguyen TQ, Sprengers D, Koeners MP, van Koppen AN, Joles JA, Goldschmeding R, Kok RJ (2016) Rapid hepatic clearance of full length CCN-2/CTGF: a putative role for LRP1-mediated endocytosis. J Cell Commun Signal 10:295–303
Article CAS PubMed PubMed Central Google Scholar
Gray AM, Mason AJ (1990) Requirement for activin a and transforming growth factor–beta 1 pro-regions in homodimer assembly. Science 247:1328–1330
Article CAS PubMed Google Scholar
Greenaway J, Lawler J, Moorehead R, Bornstein P, LaM
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