Figure 1. Breakdown of blood cultures submitted to the National Health Laboratory Service microbiology laboratories in South Africa, 2016–2020 (N = 2,575,936). ESKAPE: Acinetobacter baumannii complex (ABC): A. baumannii, A. baumannii complex; Enterococci: E. avium, E. casselifalvus, E. cecorum, E. columbae, E. durans, E. faecalis, E. faecium, E. gallinarum, E. hirae, E. raffinosus, other E. species; Escherichia coli; Klebsiella pneumonia (KP) complex: K. pneumoniae, K. pneumoniae subsp ozaenae, K. pneumoniae subsp pneumoniae, K. pneumoniae subsp rhinoscleromatis; Pseudomonas aeruginosa; Staphylococcus aureus.

Figure 1. Breakdown of blood cultures submitted to the National Health Laboratory Service microbiology laboratories in South Africa, 2016–2020 (N = 2,575,936). ESKAPE: Acinetobacter baumannii complex (ABC): A. baumannii, A. baumannii complex; Enterococci: E. avium, E. casselifalvus, E. cecorum, E. columbae, E. durans, E. faecalis, E. faecium, E. gallinarum, E. hirae, E. raffinosus, other E. species; Escherichia coli; Klebsiella pneumonia (KP) complex: K. pneumoniae, K. pneumoniae subsp ozaenae, K. pneumoniae subsp pneumoniae, K. pneumoniae subsp rhinoscleromatis; Pseudomonas aeruginosa; Staphylococcus aureus.

Figure 2. Distribution of cases with ESKAPE pathogens isolated from blood cultures in South Africa from 2016 to 2020 (n = 130,352). Enterococci identified included: E. avium, E. casselifalvus, E. cecorum, E. columbae, E. durans, E. faecalis, E. faecium, E. gallinarum, E. hirae, E. raffinosus, and other E. species. Total = represents all ESKAPE pathogens from 2016–2020.

Figure 2. Distribution of cases with ESKAPE pathogens isolated from blood cultures in South Africa from 2016 to 2020 (n = 130,352). Enterococci identified included: E. avium, E. casselifalvus, E. cecorum, E. columbae, E. durans, E. faecalis, E. faecium, E. gallinarum, E. hirae, E. raffinosus, and other E. species. Total = represents all ESKAPE pathogens from 2016–2020.

Figure 3. Distribution of cases with Enterococcus species isolated from blood cultures in South Africa from 2016 to 2020 (n = 21,339). Other enterococci included: E. avium, E. casselifalvus, E. cecorum, E. columbae, E. durans, E. gallinarum, E. hirae, E. raffinosus, and E. species.

Figure 3. Distribution of cases with Enterococcus species isolated from blood cultures in South Africa from 2016 to 2020 (n = 21,339). Other enterococci included: E. avium, E. casselifalvus, E. cecorum, E. columbae, E. durans, E. gallinarum, E. hirae, E. raffinosus, and E. species.

Figure 4. Antimicrobial susceptibility profiles for all Enterococcus species bloodstream infection isolates in South Africa, from 2016 to 2020 (n = 21,339). Other enterococci included: E. avium, E. casselifalvus, E. cecorum, E. columbae, E. durans, E. gallinarum, E. hirae, E. raffinosus, other E. species (n = 1185).

Figure 4. Antimicrobial susceptibility profiles for all Enterococcus species bloodstream infection isolates in South Africa, from 2016 to 2020 (n = 21,339). Other enterococci included: E. avium, E. casselifalvus, E. cecorum, E. columbae, E. durans, E. gallinarum, E. hirae, E. raffinosus, other E. species (n = 1185).

Table 1. Demographic characteristics of cases with enterococci isolated from blood cultures in South Africa from 2016 to 2020 (n = 21,339).

Table 1. Demographic characteristics of cases with enterococci isolated from blood cultures in South Africa from 2016 to 2020 (n = 21,339).

CharacteristicNumber of Cases (N = 21,339)n%Year 2016355216.72017351316.52018424019.92019445120.92020558326.2Sex Female10,31948.4Male10,07347.2Unknown9474.4Age categories (in years) Median age (range)2 (0–115) <1913242.81–512665.96–175822.718–64674531.6>6517738.3Unknown18418.6Province Eastern Cape19539.2Free State15137.1Gauteng941544.1KwaZulu-Natal457621.4Limpopo8293.9Mpumalanga6663.1North West5352.5Northern Cape2000.9Western Cape16007.5Unknown520.2Enterococci distribution E. avium710.3E. casselifalvus1430.7E. cecorum70.0E. columbae50.0E. durans1050.5E. durans/hirae20.0E. faecalis10,66850.0E. faecium948644.5E. gallinarum3571.7E. hirae670.3E. raffinosus220.1E. species4061.9