Meta-regression Analysis of Study Heterogeneity for Systemic Outcomes after Periodontal Therapy

Baker, WL, White, CM, Cappelleri, JC, Kluger, J, Coleman, CI. 2009. Health Outcomes, Policy, and Economics (HOPE) Collaborative Group. Understanding heterogeneity in meta-analysis: the role of meta-regression. Int J Clin Pract. 63(10):1426–1434.
Google Scholar | Crossref | Medline | ISI Beck, J, Garcia, R, Heiss, G, Vokonas, PS, Offenbacher, S. 1996. Periodontal disease and cardiovascular disease. J Periodontol. 67(Suppl 10S):1123–1137.
Google Scholar | Crossref Chen, L, Luo, G, Xuan, D, Wei, B, Liu, F, Li, J, Zhang, J. 2012. Effects of non-surgical periodontal treatment on clinical response, serum inflammatory parameters, and metabolic control in patients with type 2 diabetes: a randomized study. J Periodontol. 83(4):435–443.
Google Scholar | Crossref | Medline Chinn, S . 2000. A simple method for converting an odds ratio to effect size for use in meta-analysis. Stat Med. 19(22):3127–3131.
Google Scholar | Crossref | Medline | ISI Dechartres, A, Trinquart, L, Faber, T, Ravaud, P. 2016. Empirical evaluation of which trial characteristics are associated with treatment effect estimates. J Clin Epidemiol. 77:24–37.
Google Scholar | Crossref | Medline Eke, PI, Dye, BA, Wei, L, Slade, GD, Thornton-Evans, GO, Borgnakke, WS, Taylor, GW, Page, RC, Beck, JD, Genco, RJ. 2015. Update on prevalence of periodontitis in adults in the United States: NHANES 2009 to 2012. J Periodontol. 86(5):611–622.
Google Scholar | Crossref | Medline | ISI Engebretson, S, Kocher, T. 2013. Evidence that periodontal treatment improves diabetes outcomes: a systematic review and meta-analysis. J Periodontol. 84(4 Suppl):S153–S169.
Google Scholar | Crossref | Medline | ISI Engebretson, SP, Hyman, LG, Michalowicz, BS, Schoenfeld, ER, Gelato, MC, Hou, W, Seaquist, ER, Reddy, MS, Lewis, CE, Oates, TW, et al. 2013. The effect of nonsurgical periodontal therapy on hemoglobin A1c levels in persons with type 2 diabetes and chronic periodontitis: a randomized clinical trial. JAMA. 310(23):2523–2532.
Google Scholar | Crossref | Medline | ISI Faggion, CM, Cullinan, MP, Atieh, M. 2016. An overview of systematic reviews on the effectiveness of periodontal treatment to improve glycaemic control. J Periodontal Res. 51(6):716–725.
Google Scholar | Crossref | Medline Fogacci, MF, Vettore, MV, Thomé Leão, AT. 2011. The effect of periodontal therapy on preterm low birth weight: a meta-analysis. Obstet Gynecol. 117(1):153–165.
Google Scholar | Crossref | Medline Haidich, AB . 2010. Meta-analysis in medical research. Hippokratia. 14(Suppl 1):29–37.
Google Scholar | Medline Higgins, JPT, Li, T, Deeks, JJ. Chapter 6: Choosing effect measures and computing estimates of effect. In: Higgins, JPT, Thomas, J, Chandler, J, Cumpston, M, Li, T, Page, MJ, Welch, VA, editors. Cochrane handbook for systematic reviews of interventions, version 6.2 (updated February 2021). Cochrane, 2021. Available from: www.training.cochrane.org/handbook
Google Scholar Ioannidis, JP, Haidich, AB, Pappa, M, Pantazis, N, Kokori, SI, Tektonidou, MG, Contopoulos-Ioannidis, DG, Lau, J. 2001. Comparison of evidence of treatment effects in randomized and nonrandomized studies. JAMA. 286(7):821–830.
Google Scholar | Crossref | Medline | ISI Jeffcoat, M, Parry, S, Sammel, M, Clothier, B, Catlin, A, Macones, G. 2011. Periodontal infection and preterm birth: successful periodontal therapy reduces the risk of preterm birth. BJOG. 118(2):250–256.
Google Scholar | Crossref | Medline Jiang, H, Xiong, X, Su, Y, Peng, J, Zhu, X, Wang, J, Chen, M, Qian, X. 2016. Use of antiseptic mouthrinse during pregnancy and pregnancy outcomes: a randomised controlled clinical trial in rural China. BJOG. 123(Suppl 3):39–47.
Google Scholar | Crossref | Medline Jones, JA, Miller, DR, Wehler, CJ, Rich, SE, Krall-Kaye, EA, McCoy, LC, Christiansen, CL, Rothendler, JA, Garcia, RI. 2007. Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study. J Clin Periodontol. 34(1):46–52.
Google Scholar | Crossref | Medline Jüni, P, Witschi, A, Bloch, R, Egger, M. 1999. The hazards of scoring the quality of clinical trials for meta-analysis. JAMA. 282(11):1054–1060.
Google Scholar | Crossref | Medline | ISI Kapellas, K, Mejia, G, Bartold, PM, Skilton, MR, Maple-Brown, LJ, Slade, GD, O’Dea, K, Brown, A, Celermajer, DS, Jamieson, LM. 2017. Periodontal therapy and glycaemic control among individuals with type 2 diabetes: reflections from the PerioCardio study. Int J Dent Hyg. 15(4):e42–e51.
Google Scholar | Crossref | Medline Katagiri, S, Nitta, H, Nagasawa, T, Uchimura, I, Izumiyama, H, Inagaki, K, Kikuchi, T, Noguchi, T, Kanazawa, M, Matsuo, A, et al. 2009. Multi-center intervention study on glycohemoglobin (HbA1c) and serum, high-sensitivity CRP (hs-CRP) after local anti-infectious periodontal treatment in type 2 diabetic patients with periodontal disease. Diabetes Res Clin Pract. 83(3):308–315.
Google Scholar | Crossref | Medline Khader, YS, Al Habashneh, R, Al Malalheh, M, Bataineh, A. 2010. The effect of full-mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial. J Periodontal Res. 45(6):741–747.
Google Scholar | Crossref | Medline Kim, AJ, Lo, AJ, Pullin, DA, Thornton-Johnson, DS, Karimbux, NY. 2012. Scaling and root planing treatment for periodontitis to reduce preterm birth and low birth weight: a systematic review and meta-analysis of randomized controlled trials. J Periodontol. 83(12):1508–1519.
Google Scholar | Crossref | Medline Lavigne, SE, Forrest, JL. 2020. An umbrella review of systematic reviews of the evidence of a causal relationship between periodontal disease and adverse pregnancy outcomes: a position paper from the Canadian Dental Hygienists Association. Can J Dent Hyg. 54(2):92–100.
Google Scholar | Medline Lavigne, SE, Forrest, JL. 2021. An umbrella review of systematic reviews examining the relationship between type 2 diabetes and periodontitis: position paper from the Canadian Dental Hygienists Association. Can J Dent Hyg. 55(1):57–67.
Google Scholar | Medline Liew, AK, Punnanithinont, N, Lee, YC, Yang, J. 2013. Effect of non-surgical periodontal treatment on HbA1c: a meta-analysis of randomized controlled trials. Aust Dent J. 58(3):350–357.
Google Scholar | Crossref | Medline | ISI Lopez, NJ . 2014. Comments about the paper “Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: a randomized controlled clinical trial.” Clin Oral Investig. 18(1):343–344.
Google Scholar | Crossref | Medline López, NJ, Smith, PC, Gutierrez, J. 2002. Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: a randomized controlled trial. J Periodontol. 73(8):911–924.
Google Scholar | Crossref | Medline López, NJ, Uribe, S, Martinez, B. 2015. Effect of periodontal treatment on preterm birth rate: a systematic review of meta-analyses. Periodontology 2000. 67(1):87–130.
Google Scholar | Crossref Polyzos, NP, Polyzos, IP, Mauri, D, Tzioras, S, Tsappi, M, Cortinovis, I, Casazza, G. 2009. Effect of periodontal disease treatment during pregnancy on preterm birth incidence: a meta-analysis of randomized trials. Am J Obstet Gynecol. 200(3):225–232.
Google Scholar | Crossref | Medline Reddy, BV, Tanneeru, S, Chava, VK. 2014. The effect of phase-I periodontal therapy on pregnancy outcome in chronic periodontitis patients. J Obstet Gynaecol. 34(1):29–32.
Google Scholar | Crossref | Medline Savovic, J, Turner, RM, Mawdsley, D, Jones, HE, Beynon, R, Higgins, JPT, Sterne, JAC. 2018. Association between risk-of-bias assessments and results of randomized trials in Cochrane reviews: the ROBES Meta-Epidemiologic Study. Am J Epidemiol. 187(5):1113–1122.
Google Scholar | Crossref | Medline Schwendicke, F, Karimbux, N, Allareddy, V, Gluud, C. 2015. Periodontal treatment for preventing adverse pregnancy outcomes: a meta- and trial sequential analysis. PLoS One. 10(6):e0129060.
Google Scholar | Crossref | Medline Sgolastra, F, Severino, M, Pietropaoli, D, Gatto, R, Monaco, A. 2013. Effectiveness of periodontal treatment to improve metabolic control in patients with chronic periodontitis and type 2 diabetes: a meta-analysis of randomized clinical trials. J Periodontol. 84(7):958–973.
Google Scholar | Crossref | Medline | ISI Singh, S, Kumar, V, Kumar, S, Subbappa, A. 2008. The effect of periodontal therapy on the improvement of glycemic control in patients with type 2 diabetes mellitus: a randomized controlled clinical trial. Int J Diabetes Dev Ctries. 28(2):38–44.
Google Scholar | Crossref | Medline Stern, MP . 1995. Diabetes and cardiovascular disease. The “common soil” hypothesis. Diabetes. 44(4):369–374.
Google Scholar | Crossref | Medline | ISI Telgi, RL, Tandon, V, Tangade, PS, Tirth, A, Kumar, S, Yadav, V. 2013. Efficacy of nonsurgical periodontal therapy on glycaemic control in type II diabetic patients: a randomized controlled clinical trial. J Periodontal Implant Sci. 43(4):177–182.
Google Scholar | Crossref | Medline Uppal, A, Uppal, S, Pinto, A, Dutta, M, Shrivatsa, S, Dandolu, V, Mupparapu, M. 2010. The effectiveness of periodontal disease treatment during pregnancy in reducing the risk of experiencing preterm birth and low birth weight: a meta-analysis. J Am Dent Assoc. 141(12):1423–1434.
Google Scholar | Crossref | Medline Weidlich, P, Moreira, CH, Fiorini, T, Musskopf, ML, da Rocha, JM, Oppermann, ML, Aass, AM, Gjermo, P, Susin, C, Rösing, CK, et al. 2014. Response to a letter to the editor addressing the publication “Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: a randomized controlled clinical trial.” Clin Oral Investig. 18(1):345–346.
Google Scholar | Crossref | Medline

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