Serum exosomal miR-451a acts as a candidate marker for pancreatic cancer

1. Mizrahi, JD, Surana, R, Valle, JW, et al. Pancreatic cancer. Lancet 2020; 395: 2008–2020.
Google Scholar | Crossref | Medline2. Zhu, H, Wei, M, Xu, J, et al. PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications. Mol Cancer 2020; 19: 49.
Google Scholar | Crossref | Medline3. Schizas, D, Charalampakis, N, Kole, C, et al. Immunotherapy for pancreatic cancer: a 2020 update. Cancer Treat Rev 2020; 86: 102016.
Google Scholar | Crossref | Medline4. Pereira, SP, Oldfield, L, Ney, A, et al. Early detection of pancreatic cancer. Lancet Gastroenterol Hepatol 2020; 5: 698–710.
Google Scholar | Crossref | Medline5. Zhang, L, Sanagapalli, S, Stoita, A. Challenges in diagnosis of pancreatic cancer. World J Gastroenterol 2018; 24: 2047–2060.
Google Scholar | Crossref | Medline6. Scarà, S, Bottoni, P, Scatena, R. CA 19-9: biochemical and clinical aspects. Adv Exp Med Biol 2015; 867: 247–260.
Google Scholar | Crossref | Medline7. Wang, ZY, Ding, XQ, Zhu, H, et al. KRAS Mutant allele fraction in circulating cell-free DNA correlates with clinical stage in pancreatic cancer patients. Front Oncol 2019; 9: 1295.
Google Scholar | Crossref | Medline8. Bebelman, MP, Bun, P, Huveneers, S, et al. Real-time imaging of multivesicular body-plasma membrane fusion to quantify exosome release from single cells. Nat Protoc 2020; 15: 102–121.
Google Scholar | Crossref | Medline9. Yang, F, Ning, Z, Ma, L, et al. Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts. Mol Cancer 2017; 16: 148.
Google Scholar | Crossref | Medline10. Chen, J, Zhang, H, Chen, Y, et al. miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT. Exp Cell Res 2017; 352: 104–112.
Google Scholar | Crossref | Medline11. Fang, T, Lv, H, Lv, G, et al. Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer. Nat Commun 2018; 9: 191.
Google Scholar | Crossref | Medline12. Krol, J, Loedige, I, Filipowicz, W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 2010; 11: 597–610.
Google Scholar | Crossref | Medline | ISI13. Goodall, GJ, Wickramasinghe, VO. RNA In cancer. Nat Rev Cancer 2021; 21: 22–36.
Google Scholar | Crossref | Medline14. Ariston Gabriel, AN, Wang, F, Jiao, Q, et al. The involvement of exosomes in the diagnosis and treatment of pancreatic cancer. Mol Cancer 2020; 19: 132.
Google Scholar | Crossref | Medline15. Clancy, C, Joyce, MR, Kerin, MJ. The use of circulating microRNAs as diagnostic biomarkers in colorectal cancer. Cancer Biomark 2015; 15: 103–113.
Google Scholar | Crossref | Medline16. Siegel, RL, Miller, KD, Fuchs, HE, et al. Cancer statistics, 2021. CA Cancer J Clin 2021; 71: 7–33.
Google Scholar | Crossref | Medline17. Matsubayashi, H, Ishiwatari, H, Sasaki, K, et al. Detecting early pancreatic cancer: current problems and future prospects. Gut Liver 2020; 14: 30–36.
Google Scholar | Crossref | Medline18. McGuigan, A, Kelly, P, Turkington, RC, et al. Pancreatic cancer: a review of clinical diagnosis, epidemiology, treatment and outcomes. World J Gastroenterol 2018; 24: 4846–4861.
Google Scholar | Crossref | Medline19. Carmicheal, J, Hayashi, C, Huang, X, et al. Label-free characterization of exosome via surface enhanced Raman spectroscopy for the early detection of pancreatic cancer. Nanomedicine 2019; 16: 88–96.
Google Scholar | Crossref | Medline20. Zöller, M . Pancreatic cancer diagnosis by free and exosomal miRNA. World J Gastrointest Pathophysiol 2013; 4: 74–90.
Google Scholar | Crossref | Medline21. Ko, J, Bhagwat, N, Yee, SS, et al. Combining machine learning and nanofluidic technology to diagnose pancreatic cancer using exosomes. ACS Nano 2017; 11: 11182–11193.
Google Scholar | Crossref | Medline22. Li, W, Li, C, Zhou, T, et al. Role of exosomal proteins in cancer diagnosis. Mol Cancer 2017; 16: 145.
Google Scholar | Crossref | Medline23. Lan, B, Zeng, S, Grützmann, R, et al. The role of exosomes in pancreatic cancer. Int J Mol Sci 2019; 20: 4332.
Google Scholar | Crossref24. Lu, L, Risch, HA. Exosomes: potential for early detection in pancreatic cancer. Future Oncol 2016; 12: 1081–1090.
Google Scholar | Crossref | Medline25. Taller, D, Richards, K, Slouka, Z, et al. On-chip surface acoustic wave lysis and ion-exchange nanomembrane detection of exosomal RNA for pancreatic cancer study and diagnosis. Lab Chip 2015; 15: 1656–1666.
Google Scholar | Crossref | Medline | ISI26. Lai, X, Wang, M, McElyea, SD, et al. A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. Cancer Lett 2017; 393: 86–93.
Google Scholar | Crossref | Medline | ISI27. Vicentini, C, Calore, F, Nigita, G, et al. Exosomal miRNA signatures of pancreatic lesions. BMC Gastroenterol 2020; 20: 137.
Google Scholar | Crossref | Medline28. Que, R, Ding, G, Chen, J, et al. Analysis of serum exosomal microRNAs and clinicopathologic features of patients with pancreatic adenocarcinoma. World J Surg Oncol 2013; 11: 219.
Google Scholar | Crossref | Medline29. Xu, YF, Hannafon, BN, Zhao, YD, et al. Plasma exosome miR-196a and miR-1246 are potential indicators of localized pancreatic cancer. Oncotarget 2017; 8: 77028–77040.
Google Scholar | Crossref | Medline30. Abue, M, Yokoyama, M, Shibuya, R, et al. Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer. Int J Oncol 2015; 46: 539–547.
Google Scholar | Crossref | Medline31. Zhao, S, Li, J, Zhang, G, et al. Exosomal miR-451a functions as a tumor suppressor in hepatocellular carcinoma by targeting LPIN1. Cell Physiol Biochem 2019; 53: 19–35.
Google Scholar | Crossref | Medline32. Kanaoka, R, Iinuma, H, Dejima, H, et al. Usefulness of plasma exosomal MicroRNA-451a as a noninvasive biomarker for early prediction of recurrence and prognosis of non-small cell lung cancer. Oncology 2018; 94: 311–323.
Google Scholar | Crossref | Medline33. Goto, T, Fujiya, M, Konishi, H, et al. An elevated expression of serum exosomal microRNA-191, −21, −451a of pancreatic neoplasm is considered to be efficient diagnostic marker. BMC Cancer 2018; 18: 116.
Google Scholar | Crossref | Medline34. Takahasi, K, Iinuma, H, Wada, K, et al. Usefulness of exosome-encapsulated microRNA-451a as a minimally invasive biomarker for prediction of recurrence and prognosis in pancreatic ductal adenocarcinoma. J Hepatobiliary Pancreat Sci 2018; 25: 155–161.
Google Scholar | Crossref | Medline35. Kawamura, S, Iinuma, H, Wada, K, et al. Exosome-encapsulated microRNA-4525, microRNA-451a and microRNA-21 in portal vein blood is a high-sensitive liquid biomarker for the selection of high-risk pancreatic ductal adenocarcinoma patients. J Hepatobiliary Pancreat Sci 2019; 26: 63–72.
Google Scholar | Crossref | Medline

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