1. Cappariello, A, Maurizi, A, Veeriah, V, Teti, A. The Great Beauty of the osteoclast. Arch Biochem Biophys. 2014;558:70–8. doi:10.1016/j.abb.2014.06.017.
Google Scholar | Crossref2. Udagawa, N, Koide, M, Nakamura, M, Nakamichi, Y, Yamashita, T, Uehara, S, Kobayashi, Y, Furuya, Y, Yasuda, H, Fukuda, C, Tsuda, E. Osteoclast differentiation by RANKL and OPG signaling pathways. J Bone Miner Metab. 2021;39(1):19–26. doi:10.1007/s00774-020-01162-6.
Google Scholar | Crossref3. Arana-Chavez, VE, Bradaschia-Correa, V. Clastic cells: mineralized tissue resorption in health and disease. Int J Biochem Cell Biol. 2009;41(3):446–50. doi:10.1016/j.biocel.2008.09.007.
Google Scholar | Crossref4. Rogers, MJ, Crockett, JC, Coxon, FP, Mönkkönen, J. Biochemical and molecular mechanisms of action of bisphosphonates. Bone. 2011;49(1):34–41. doi:10.1016/j.bone.2010.11.008.
Google Scholar | Crossref | Medline5. Cummings, SR, Santora, AC, Black, DM, Russell, RGG. History of alendronate. Bone. 2020;137:115411. doi:10.1016/j.bone.2020.115411.
Google Scholar | Crossref6. Martins, CA, Leyhausen, G, Volk, J, Geurtsen, W. Effects of alendronate on osteoclast formation and activity in vitro. J Endod. 2015;41(1):45–9. doi:10.1016/j.joen.2014.07.010.
Google Scholar | Crossref7. Hachemi, Y, Rapp, AE, Picke, AK, Weidinger, G, Ignatius, A, Tuckermann, J. Molecular mechanisms of glucocorticoids on skeleton and bone regeneration after fracture. J Mol Endocrinol. 2018;61(1):R75–90. doi:10.1530/JME-18-0024.
Google Scholar | Crossref8. Jiang, Y, Lu, Y, Jiang, X, Hu, J, Li, R, Liu, Y, Zhu, G, Rong, X. Glucocorticoids induce osteoporosis mediated by glucocorticoid receptor-dependent and -independent pathways. Biomed Pharmacother. 2020;125:109979. doi:10.1016/j.biopha.2020.109979.
Google Scholar | Crossref9. Sousa, LH, Moura, EV, Queiroz, AL, Val, D, Chaves, H, Lisboa, M, Furlaneto, F, Brito, GA, Goes, P. Effects of glucocorticoid-induced osteoporosis on bone tissue of rats with experimental periodontitis. Arch Oral Biol. 2017;77:55–61. doi:10.1016/j.archoralbio.2017.01.014.
Google Scholar | Crossref10. Pereira, RM, Delany, AM, Canalis, E. Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture. Bone. 2001;28(5):484–90. doi:10.1016/s8756-3282(01)00422-7.
Google Scholar | Crossref11. Kim, HJ, Zhao, H, Kitaura, H, Bhattacharyya, S, Brewer, JA, Muglia, LJ, Patrick Ross, F, Teitelbaum, SL. Glucocorticoids and the osteoclast. Ann NY Acad Sci. 2007;1116:335–9. doi:10.1196/annals.1402.057.
Google Scholar | Crossref12. Hayashi, K, Yamaguchi, T, Yano, S, Kanazawa, I, Yamauchi, M, Yamamoto, M, Sugimoto, T. BMP/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: potential therapeutic targets for glucocorticoid-induced osteoporosis. Biochem Biophys Res Commun. 2009;379(2):261–6. doi:10.1016/j.bbrc.2008.12.035.
Google Scholar | Crossref13. Pasqualetti, S, Congiu, T, Banfi, G, Mariotti, M. Alendronate rescued osteoporotic phenotype in a model of glucocorticoid-induced osteoporosis in adult zebrafish scale. Int J Exp Pathol. 2015;96(1):11–20. doi:10.1111/iep.12106.
Google Scholar | Crossref14. Al Deeb, SK, Hamdan, II, Al Najjar, SM. Spectroscopic and HPLC methods for the determination of alendronate in tablets and urine. Talanta. 2004;64(3):695–702. doi:10.1016/j.talanta.2004.03.044.
Google Scholar | Crossref15. Holliday, LS, Dean, AD, Greenwald, JE, Glucks, SL. C-type natriuretic peptide increases bone resorption in 1,25-dihydroxyvitamin D3-stimulated mouse bone marrow cultures. J Biol Chem. 1995;270(32):18983–9. doi:10.1074/jbc.270.32.18983.
Google Scholar | Crossref16. Violich, DR, Chandler, NP. The smear layer in endodontics—a review. Int Endod J. 2010;43(1):2–15. doi:10.1111/j.1365-2591.2009.01627.x.
Google Scholar | Crossref17. Rogers, MJ, Mönkkönen, J, Munoz, MA. Molecular mechanisms of action of bisphosphonates and new insights into their effects outside the skeleton. Bone. 2020;139:115493. doi:10.1016/j.bone.2020.115493.
Google Scholar | Crossref18. Breuil, V, Cosman, F, Stein, L, Horbert, W, Nieves, J, Shen, V, Lindsay, R, Dempster, DW. Human osteoclast formation and activity in vitro: effects of alendronate. J Bone Miner Res. 1998;13(11):1721–9. doi:10.1359/jbmr.1998.13.11.1721.
Google Scholar | Crossref19. Giuliani, N, Pedrazzoni, M, Negri, G, Passeri, G, Impicciatore, M, Girasole, G. Bisphosphonates stimulate formation of osteoblast precursors and mineralized nodules in murine and human bone marrow cultures in vitro and promote early osteoblastogenesis in young and aged mice in vivo. Bone. 1998;22(5):455–61. doi:10.1016/s8756-3282(98)00033-7.
Google Scholar | Crossref20. Weinstein, RS, Chen, JR, Powers, CC, Stewart, SA, Landes, RD, Bellido, T, Jilka, RL, Parfitt, AM, Manolagas, SC. Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids. J Clin Invest. 2002;109(8):1041–8. doi:10.1172/JCI14538.
Google Scholar | Crossref21. Shi, J, Wang, L, Zhang, H, Jie, Q, Li, X, Shi, Q, Huang, Q, Gao, B, Han, Y, Guo, K, Liu, J, Yang, L, Luo, Z. Glucocorticoids: dose-related effects on osteoclast formation and function via reactive oxygen species and autophagy. Bone. 2015;79:222–32. doi:10.1016/j.bone.2015.06.014.
Google Scholar | Crossref22. Wang, L, Heckmann, BL, Yang, X, Long, H. Osteoblast autophagy in glucocorticoid-induced osteoporosis. J Cell Physiol. 2019;234(4):3207–15. doi:10.1002/jcp.27335.
Google Scholar | Crossref23. Mak, W, Shao, X, Dunstan, CR, Seibel, MJ, Zhou, H. Biphasic glucocorticoid-dependent regulation of Wnt expression and its inhibitors in mature osteoblastic cells. Calcif Tissue Int. 2009;85(6):538–45. doi:10.1007/s00223-009-9303-1.
Google Scholar | Crossref24. Hildebrandt, S, Baschant, U, Thiele, S, Tuckermann, J, Hofbauer, LC, Rauner, M. Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo. Sci Rep. 2018;8(1):8711. doi:10.1038/s41598-018-26300-z.
Google Scholar | Crossref25. Henneicke, H, Gasparini, SJ, Brennan-Speranza, TC, Zhou, H, Seibel, MJ. Glucocorticoids and bone: local effects and systemic implications. Trends Endocrinol Metab. 2014;25(4):197–211. doi:10.1016/j.tem.2013.12.006.
Google Scholar | Crossref26. Inoue, M, Matsumoto, C, Nakajima, K, Kuroshima, S, Sawase, T. Alendronate/dexamethasone combination therapy worsens soft and hard tissue wound healing around implants in rat maxillae. Bone. 2021;148:115942. doi:10.1016/j.bone.2021.115942.
Google Scholar | Crossref27. Seedor, JG, Quartuccio, HA, Thompson, DD. The bisphosphonate alendronate (MK-217) inhibits bone loss due to ovariectomy in rats. J Bone Miner Res. 1991;6(4):339–46. doi:10.1002/jbmr.5650060405.
Google Scholar | Crossref