OPINION ARTICLE

Abbreviations In Medical Writings: Do They Also Abbreviate Our Science?
Dimitrios Moris; pp 1274-1276 (Pubmed Abstract, PDF)

SPECIAL ARTICLE

Behind the numbers and the panic of a viral pandemic: fixed restrictive oncology guidance may jeopardize patients’ survival

Davide Mauri, Dimitrios Tzachanis, Antonis Valachis, Konstantinos Kamposioras, Maria Tolia, Mario Dambrosio, Georgios Zarkavelis, Stefania Gkoura, Ioanna Gazouli, Francesco De Lorenzo and Kathi Apostolidis on behalf of an International Oncology Panel, FAVO and ECPC; pp 1277-1280 (Pubmed Abstract, PDF)

REVIEW ARTICLES

Current trends in the management and prevention of human papillomavirus (HPV) infection

Ioannis Ntanasis-Stathopoulos, Anastasios Kyriazoglou, Michalis Liontos, Meletios A. Dimopoulos, Maria Gavriatopoulou; pp 1281-1285 (Pubmed Abstract, PDF)

Adverse effects of androgen deprivation therapy in patients with prostate cancer: Focus on muscle and bone health

Alexandra Bargiota, Athanasios Oeconomou, Ioannis Zachos, Michel Samarinas, Luis L.Pisters, Vassilios Tzortzis; pp 1286-1294 (Pubmed Abstract, PDF)

Human Papilloma Virus infection and breast cancer development: Challenging theories and controversies with regard to their potential association

Aikaterini Mastoraki, Dimitrios Schizas, Anastasia Gkiala, Vasiliki Ntella, Natasha Hasemaki, Ioanna Pentara,Vasileia Ntomi, Alkistis Kapelouzou,Theodore Liakakos; pp 1295-1301 (Pubmed Abstract, PDF)

Insulinomas: from diagnosis to treatment. A review of the literature

Dimitrios Giannis, Dimitrios Moris, Georgia-Sofia Karachaliou, Diamantis I. Tsilimigras, Georgios Karaolanis, Alexandros Papalampros, Evangelos Felekouras; 1302-1314 (Pubmed Abstract, PDF)

ORIGINAL ARTICLES

BREAST CANCER

Two hypofractionated schedules for early stage breast cancer: Comparative retrospective analysis for acute and late radiation induced dermatitis

Anna Zygogianni, John Gogalis, Ioannis Georgakopoulos, Styliani Nikoloudi,  Zoi Liakouli, Andromachi Kougioumtzopoulou, Despoina Alexiou, Christos Antypas, Christina Armpilia, Maria Protopapa, Lia-Angela Moulopoulou, Vassilis Kouloulias; pp 1315-1322 (Pubmed Abstract, PDF)

Lanostane inhibits the proliferation and bone metastasis of human breast cancer cells via inhibition of Rho-associated kinase signaling

Yiqun Du, Wangjun Yan, Zhicheng Wang, Chenchen Wang, Mingzhu Huang, Zhonghua Tao, Zhiqiang Wu; pp 1323-29 (Pubmed Abstract, PDF)

Artemisinin induces selective and potent anticancer effects in drug resistant breast cancer cells by inducing cellular apoptosis and autophagy and G2/M cell cycle arrest 

Xing Guan, Yan Guan; pp 1330-1337 (Pubmed Abstract, PDF)

Genetic screening results of individuals with high risk BRCA-related breast/ovarian cancer in Trakya region of Turkey

Selma Demir, Hilmi Tozkir, Hakan Gurkan, E. Ikbal Atli, Sinem Yalcintepe, Engin Atli, Y. Atakan Sezer, Damla Eker, Nermin Tuncbilek, Ebru Tastekin, Yasemin Ozen, Irfan Cicin; pp 1337-1347 (Pubmed Abstract, PDF)

Gemcitabine plus capecitabine in elderly patients with anthracycline- and taxane-pretreated metastatic breast cancer

Ningning Dong, Yongdong Wu, Chenxin Song, Mingyu Wang, Yue Jiao, Shutian Zhang; pp 1348-1353 (Pubmed Abstract, PDF)

Analysis of the health situation of women referring to breast cancer screening in Poland

Malgorzata Pasek, Julia Plachta, Helena Kaducakova, Grazyna Debska; pp 1354-1360 (Pubmed Abstract, PDF)

HEPATOCELLULAR CARCINOMA

Reduced glutathione ameliorates liver function,oxidative stress and inflammation after interventional therapy for hepatocellular carcinoma

Yang Ke, Tiangen Wu, Xuefen Lei, Cheng Zhang, Jian Zhou, Jinze Li, Heng Zhang, Xiaoxing Chen, Jiaping Wang, Lin Wang; pp 1361-1367 (Pubmed Abstract, PDF)

Effects of CircRNA-ITCH on proliferation and apoptosis of hepatocellular carcinoma cells through inhibiting Wnt/β-catenin signaling pathway

Baoming Yang, Jingru Zhao, Tiantian Huo, Manli Zhang, Xiaohui Wu; pp 1368-1374 (Pubmed Abstract, PDF)

miR-449a regulates biological functions of hepatocellular carcinoma cells by targeting SATB1

Jiarong Li, Zhipeng Zheng, Junkai Zhang, Yunqiang Tang, Xiaoping Wan; pp 1375-1382 (Pubmed Abstract, PDF)

Detailed studies on the anticancer action of rosmarinic acid in human Hep-G2 liver carcinoma cells: evaluating its effects on cellular apoptosis, caspase activation and suppression of cell migration and invasion

Boxun Jin, Jinning Liu, Daming Gao, Ying Xu, Li He, Yunjin Zang, Ning Li, Dongdong Lin; pp 1383-1389 (Pubmed Abstract, PDF)

Roles of ZEB2 and RBM38 in liver cancer stem cell proliferation

Xiaowan Yu, Wei Wang, Xiaorong Lin, Xuecong Zheng, Anqi Yang; pp 1390-1394 (Pubmed Abstract, PDF)

LINC01980 stimulates the progression of hepatocellular carcinoma via downregulating caspase 9

Yunhong Zang, Qingqiang Yi, Jindun Pan, Mingquan Ding, Xiuli Zuo, Xiumei Hu; pp 1395-1403 (Pubmed Abstract, PDF)

Laparoscopic versus open hepatectomy for elderly patients with hepatocellular carcinoma

Yajun Chen, Lili Yu, Changyin Quan; pp 1404-1412 (Pubmed Abstract, PDF)

COLORECTAL CANCER

Dendritic cell-derived exosome-entrapped fluorouracil can enhance its anti-colon cancer effect

Man Xu, Qian Chen, Juan Li, Li Peng, Ling Ding; 1413-1422 (Pubmed Abstract, PDF)

PD-L1 expression in colorectal cancer and its relationship with TLR-4 expression

Decai Chi, Wei Xu, Xuanchen Tao, Tianhua Zhang, Yunfu Cui; 1423-1429 (Pubmed Abstract, PDF)

Association of CT features with TNM stage and pathology of patients with rectal cancer and their significance in evaluation of efficacy and prognosis

Xiujie Duan, Qiang Zhao, Fuyuan Li; pp 1430-1435 (Pubmed Abstract, PDF)

Neutrophil-to-lymphocyte ratio: a hidden gem in predicting neoadjuvant treatment response in locally advanced rectal cancer?

David Andras, Dana Crisan, Rares Craciun, Andrada Nemes, Alexandra Caziuc, Radu Drasovean, Radu Seicean, Razvan Scurtu, Vasile Bințințan, Dan Eniu, Ioan Coman, George Dindelegan; pp 1436-1442 (Pubmed Abstract, PDF)

Serum microRNA-18a, MicroRNA-21 and microRNA-92a as diagnostic markers in colorectal cancer patients

Mennatallah Elaguizy, Marwa Sheta, Nahed Ibrahim, Ahmed Eltaweel, Ahmed Mostafa; pp 1443-1448 (Pubmed Abstract, PDF)

Norwogonin flavone suppresses the growth of human colon cancer cells via mitochondrial mediated apoptosis, autophagy induction and triggering G2/M phase cell cycle arrest

Zhang Wang, Qinqin Zhang, Ling Zhou, Gao Liu, Quanfeng Wu, Changwang Chen; pp 1449-1454 (Pubmed Abstract, PDF)

GASTRIC CANCER

Relationship between PRRX1, circulating tumor cells, and clinicopathological parameter in patients with gastric cancer

Yongbin Zhang, Jibin Yao, Jing Feng, Shang Wang, Zhong Yang, Wanxia Huang, Mingxu Da; 1455-1462 (Pubmed Abstract, PDF)

Anticancer effects of Lanostane against human gastric cancer cells involves autophagy, apoptosis and modulation of m-TOR/PI3K/AKT signalling pathway

Xiulan Peng, Changli Ruan, Changjiang Lei, Anbing He, Xia Wang, Renfeng Luo, Yahong Cai, Weiguo Dong, Jun Lin; pp 1463-1468 (Pubmed Abstract, PDF)

Efficacy of endostatin combined with continuous transcatheter arterial infusion and chemoembolization on gastric cancer with liver metastasis and analysis of prognosis

Long Chen, Hao Shi, Yang Che, Wanli Sun, Xiangdong Niu, Weilong Lu; pp 1469-1475 (Pubmed Abstract, PDF)

Correlations of recurrence of gastric cancer in patients after radical surgery with serum gastrointestinal hormones, vascular endothelial growth factors and serum anti-helicobacter pylori IgG antibody

Xiemin Feng, Xiaoyun Ma, Yan Shi; 1476-1481 (Pubmed Abstract, PDF)

Replication Protein A (RPA1, RPA2 and RPA3) expression in gastric cancer: correlation with clinicopathologic parameters and patients’ survival

Efi Fourtziala, Nick Givalos, Nikolaos Alexakis, John Griniatsos, Nektarios Alevizopoulos, Nikolaos Kavantzas, Andreas C Lazaris, Penelope Korkolopoulou, Hariklia Gakiopoulou; 1482-1489 (Pubmed Abstract, PDF)

LUNG CANCER

A comparative study on etoposide combined with lobaplatin or cisplatin in the first-line treatment of extensive-stage small cell lung cancer

Shujun Li, Yahai Liang, Yanxia Wu, Zhong Huang, Yanming Lin, Zhixiong Yang, Hualin Chen, Aibing Wu; 1490-1496 (Pubmed Abstract, PDF)

Comparison of efficacy of stereotactic body radiotherapy and thoracoscopic surgery in the treatment of early-stage non-small cell lung cancer

Xiaoqi Li, Chunbo Niu, Qizhang Chen, Xiaojun Chen; pp 1497-1503 (Pubmed Abstract, PDF)

Doxorubicin loaded liposomes for lung tumor targeting: in vivo cell line study in human lung cancer

Yuehui Guo, Qingyun Zhu, Jing Shi, Yanxiang Li, Daiquan Fu, Delin Qiao, Shiwei Chen, Yuwei Yang, Yane Wang; 1504-1511 (Pubmed Abstract, PDF)

Matrine induces apoptosis and autophagy in human lung adenocarcinoma cells via upregulation of Cavin3 and suppression of PI3K/AKT pathway

Qian Wan, Zhuo Du, Zhengyu Fang, Hongbin Cheng, Chunmei Li, XueFeng Zhou; 1512-1516 (Pubmed Abstract, PDF)

LINC00632 inhibits the malignant development of non-small cell lung cancer by downregulating miR-1203

Tianwen Luo, Liping Yan, Hua Liu; pp 1517-1524 (Pubmed Abstract, PDF)

GYNECOLOGIC CANCER

Efficacy and prognosis of fertility-preserved hysteroscopic surgery combined with progesterone in the treatment of complex endometrial hyperplasia and early endometrial carcinoma

Zonglan Xu, Yonghui Tian, Jinjin Fu, Jie Xu, Di Bao, Guojing Wang; pp 1525-1533 (Pubmed Abstract, PDF)

Efficacy of metformin in the treatment of estrogen-dependent endometrial carcinoma complicated with type 2 diabetes mellitus and analysis of its prognosis

Yonghong Deng, Jing Wang, Wenxia Li, Wanchun Xiong, Xiaoli Wang; pp 1534-1540 (Pubmed Abstract, PDF)

UV irradiation induces apoptosis in the human endometrial stromal cell line (ThESC)

Marijana Stanojevic-Pirkovic, Marija Andelkovic, Jovan Lukovic, Ivanka Zelen, Zoran Milosavljevic, Marija Mitrovic, Vladimir Jurisic, Ivana Nikolic; pp 1541-1546 (Pubmed Abstract, PDF)

Anticancer activity of Eremanthin against the human cervical cancer cells is due to G2/M phase cell cycle arrest, ROS-mediated necrosis-like cell death and inhibition of PI3K/AKT signalling pathway

Tingting Liu, Xiaoling Zhao, Dan Song, Yao Liu, Weimin Kong; pp 1547-1553 (Pubmed Abstract, PDF)

OSTEOSARCOMA

MEX3C promotes osteosarcoma malignant progression through negatively regulating FGF14

Yile Cao, Fan Jiang, Sheng Zhang, Lei Yang, Yu Sun; pp 1554-1561 (Pubmed Abstract, PDF)

Effects of miR-432 and miR-548c-3p on the proliferation and invasion of osteosarcoma cells

Jinghui Yao, Wei Tan, Weiping Wu, Ruolian Ye, Yibin Li, Yun Chen; pp 1562-1568 (Pubmed Abstract, PDF)

Exploring the association mechanism between metastatic osteosarcoma and non-metastatic osteosarcoma based on dysfunctionality module

Jun Xiong, Tao Li; pp 1569-1578 (Pubmed Abstract, PDF)

HEAD & NECK CANCER

MicroRNA-215 promoted the progression of nasopharyngeal carcinoma through targeting RB1 and activating Wnt/β-catenin pathway

Yuanyuan Zhang, Hui Zhang, Xiuguo Li; pp 1579-1586 (Pubmed Abstract, PDF)

Lymphoscintigraphy and radio-guided neck dissection in oral cavity squamous cell carcinoma

Nicola Malagutti, Stefano Panareo, Andrea Ciorba, Virginia Corazzi, Michela Borin, Chiara Bianchini, Francesco Stomeo, Mirco Bartolomei, Stefano Pelucchi; pp 1587-1593 (Pubmed Abstract, PDF)

HEMATOLOGIC MALIGNANCIES

Friedelin inhibits the growth and metastasis of human leukemia cells via modulation of MEK/ERK and PI3K/AKT signalling pathways 

Wei Chang, Jue Wang, Yi Xiao; pp 1594-1599 (Pubmed Abstract, PDF)

Inhibition of human leukemia cells growth by juglone is mediated via autophagy induction, endogenous ROS production, and inhibition of cell migration and invasion

Yi Xiao, Xi Ming, Jinhuang Xu; pp 1600-1606 (Pubmed Abstract, PDF)

Davanone terpenoid inhibits cisplatin-resistant acute myeloid leukemia cancer cell growth by inducing caspase-dependent apoptosis, loss of mitochondrial membrane potential, inhibition of cell migration and invasion and targeting PI3K/AKT/MAPK signalling pathway

Yi Xiao, Taoran Deng, Di Wang; pp 1607-1613 (Pubmed Abstract, PDF)

Solanine inhibits proliferation and promotes apoptosis of the human leukemia cells by targeting the miR-16/Bcl-2 axis

Yan Zheng , Lan Li , Qiuying Gao , Ben Niu , Hui Wang; pp 1614-1618 (Pubmed Abstract, PDF)

PROSTATE CANCER

Associations between the expressions of MiR-135 and MiR-92a and pathogenesis of prostate cancer and analysis of their clinical significance

Wei He, Hongchao He, Ning Zhang, Wenbin Rui, Xiaojing Wang, Yu Zhu, Xin Xie; pp 1619-1624 (Pubmed Abstract, PDF)

Early PSA response to antiandrogen therapy in metastatic castration-resistant prostate carcinoma patients: A predictive marker for progression-free survival?

Demir Atakan, Alan Ozkan, Mert Aslihan Guven, Koca Sinan; pp 1625-1630 (Pubmed Abstract, PDF)

GLIOBLASTOMA

Multiflorane suppresses the proliferation, migration and invasion of human glioblastoma by targeting MAPK signalling pathway 

Peng Qiu, Xiangrong Zheng, Hongan Yang; pp 1631-1635 (Pubmed Abstract, PDF)

BLADDER CANCER

Research on mechanism of miR-130a in regulating autophagy of bladder cancer cells through CYLD

Haitao Dai , Changmao Liu, Yuanhua Liu, Zhong Zhang, Changwei Peng, Zhongyu Wang, Jiang Zheng, Chenglong Li, Weimin Yu, Fan Cheng; pp 1636-1642 (Pubmed Abstract, PDF)

PANCREATIC CANCER

Efficacy of irreversible electroporation ablation combined with natural killer cells in treating locally advanced pancreatic cancer

Qinghua Pan, Change Hu, Yuhong Fan, Yuanzhi Wang, Ruxin Li, Xiaohua Hu; pp 1643-1649 (Pubmed Abstract, PDF)

Predictive factors of progression in renal function after unilateral nephrectomy in renal malignancy

Buyuan Guo, Yongyi Guo, Chunyan Liu; pp 1650-1657 (Pubmed Abstract, PDF)

MISCELLANEOUS

Institutional results of OncoOVARIAN Dx – a novel algorithm for the preoperative evaluation of adnexal masses

Paul Kubelac, Alexandra Craciun, Oana Jalba, Simona Gheorghe, Gabriel Lazar, Florin Ignat, Cosmin Lisencu, Alin Rancea, Catalin Vlad, Alexandru Irimie, Patriciu Achimas-Cadariu; pp 1658-1663 (Pubmed Abstract, PDF)

LETTERS TO THE EDITOR

Triple-negative breast cancer patients with isolated lung metastases and concomitant COVID-19 infection; does cytokine storm result in better efficacy?

Kadri Altundag; p 1664 (Pubmed Abstract, PDF)

Enhancing PTEN suppressor gene expression in pancreatic carcinoma

Leonidas Petrogiannopoulos, Athanasios Niotis, Theodoros Niotis, Evangelos Tsiambas;p 1664 (Pubmed Abstract, PDF)

Poor histological subtype and response to neoaadjuvant treatment in triple-negative breast cancer

Kadri Altundag;p 1664 (Pubmed Abstract, PDF)

Sentinel lymph node biopsy in papillary breast cancer; to do or not to do?

Kadri Altundag; p 1665 (Pubmed Abstract, PDF)

Diabetes mellitus as a risk factor in oral squamous cell carcinoma development

Nicholas Mastronikolis, Dimitrios Rigopoulos, Vasiliki Kordela, Evangelos Tsiambas; p 1666 (Pubmed Abstract, PDF)

Is there a role of anthracycline use in the management of de novo HER-2 positive metastatic breast cancer?

Kadri Altundag; p 1667 (Pubmed Abstract, PDF)

Specific histological subgroups in invasive lobular carcinoma might affect outcome in both chemotherapy and non-chemotherapy groups

Kadri Altundag; p 1667 (Pubmed Abstract, PDF)

Comment on Raze’s views on cancer and the introduction of chemotherapy

Kamran Mahlooji, Mahsima Abdoli; p 1667 (Pubmed Abstract, PDF)

Immunohistochemical characteristic of each foci in multifocal or multicenter breast cancers should be deciphered to determine the best adjuvant treatment of choice

Kadri Altundag; p 1668 (Pubmed Abstract, PDF)

Clinical and pathological characteristics of breast cancer patients with sarcoidosis

Kadri Altundag; p 1669 (Pubmed Abstract, PDF)