The continuing spread of SARS-CoV-2 remains a Public Health Emergency of International Concern. What physicians need to know about transmission, diagnosis, and treatment of Covid-19 is the subject of ongoing updates from infectious disease experts at the Journal.

In this audio interview conducted on August 31, 2021, the editors discuss the rising number of U.S. Covid-19 cases that has followed the loosening of restrictions and new data on the effectiveness of vaccination in controlling the increase.