Intrahepatic cholestasis of pregnancy is a liver disease that slows, or even stops, the normal flow of bile to the gallbladder. It usually occurs in the second and third trimesters of pregnancy and resolves within a few days after birth. Intrahepatic cholestasis of pregnancy causes jaundice and itching, and, more importantly, high serum bile acid concentrations, which might trigger spontaneous preterm birth or even lead to stillbirth.