Boonsawat P., Joset P., Steindl K., Oneda B., Gogoll L., Azzarello-Burri S. et al. 2019 Elucidation of the phenotypic spectrum and genetic landscape in primary and secondary microcephaly. Genet. Med. 21, 2043–2058.

Article  PubMed  PubMed Central  Google Scholar 

Choi Y. J. and Anders L. 2014 Signaling through cyclin D-dependent kinases. Oncogene 33, 1890–1903.

Article  CAS  PubMed  Google Scholar 

Ericson K. K., Krull D., Slomiany P. and Grossel M. J. 2003 Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes. Mol. Cancer Res. 1, 654–664.

CAS  PubMed  Google Scholar 

Faheem M., Naseer M. I., Rasool M., Chaudhary A. G., Kumosani T. A., Ilyas A. M. et al. 2015 Molecular genetics of human primary microcephaly: an overview. BMC Med. Genomics 8 (Suppl 1), S4.

Article  PubMed  PubMed Central  Google Scholar 

Gilmore E. C. and Walsh C. A. 2013 Genetic causes of microcephaly and lessons for neuronal development. Wiley Interdiscip. Rev. Dev. Biol. 2, 461–478.

Article  CAS  PubMed  Google Scholar 

Hussain M. S., Baig S. M., Neumann S., Peche V. S., Szczepanski S., Nurnberg G. et al. 2013 CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum. Mol. Genet. 22, 5199–5214.

Article  CAS  PubMed  Google Scholar 

Jayaraman D., Bae B. I. and Walsh C. A. 2018 The genetics of primary microcephaly. Annu. Rev. Genomics Hum. Genet. 19, 177–200.

Article  CAS  PubMed  Google Scholar 

Komai T., Kishimoto K. and Ozaki Y. 1955 Genetic study of microcephaly based on Japanese material. Am. J. Hum. Genet. 7, 51–65.

CAS  PubMed  PubMed Central  Google Scholar 

Kozakov D., Hall D. R., Xia B., Porter K. A., Padhorny D., Yueh C. et al. 2017 The ClusPro web server for protein-protein docking. Nat. Protoc. 12, 255–278.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kozar K. and Sicinski P. 2005 Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes. Cell Cycle 4, 388–391.

Article  CAS  PubMed  Google Scholar 

Laskowski R. A. and Swindells M. B. 2011 LigPlot+: multiple ligand-protein interaction diagrams for drug discovery. J. Chem. Inf. Model. 51, 2778–2786.

Article  CAS  PubMed  Google Scholar 

Lim S. and Kaldis P. 2013 Cdks, cyclins and CKIs: roles beyond cell cycle regulation. Development 140, 3079–3093.

Article  CAS  PubMed  Google Scholar 

Meyerson M. and Harlow E. 1994 Identification of G1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell Biol. 14, 2077–2086.

CAS  PubMed  PubMed Central  Google Scholar 

Morris G. M., Huey R., Lindstrom W., Sanner M. F., Belew R. K., Goodsell D. S. and Olson A. J. 2009 AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility. J. Comput. Chem. 30, 2785–2791.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Murray J. E. and Jackson A. P. 2012 Exploring microcephaly and human brain evolution. Dev. Med. Child Neurol. 54, 580–581.

Article  PubMed  Google Scholar 

Pettersen E. F., Goddard T. D., Huang C. C., Couch G. S., Greenblatt D. M., Meng E. C. and Ferrin T. E. 2004 UCSF Chimera–a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605–1612.

Article  CAS  PubMed  Google Scholar 

Szklarczyk D., Franceschini A., Wyder S., Forslund K., Heller D., Huerta-Cepas J. et al. 2015 STRING v10: protein-protein interaction networks, integrated over the tree of life. Nucleic Acids Res. 43, D447–D452.

Article  CAS  PubMed  Google Scholar 

Tigan A. S., Bellutti F., Kollmann K., Tebb G. and Sexl V. 2016 CDK6-a review of the past and a glimpse into the future: from cell-cycle control to transcriptional regulation. Oncogene 35, 3083–3091.

Article  CAS  PubMed  Google Scholar 

Trott O. and Olson A. J. 2010 AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J. Comput. Chem. 31, 455–461.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Woods C. G., Bond J. and Enard W. 2005 Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings. Am. J. Hum. Genet. 76, 717–728.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang, J. and Zhang Y. 2015 Protein structure and function prediction using I-TASSER. Curr. Protoc. Bioinform. 52, 5.8.1-5.8.15.