Diffuse midline glioma, H3K27-altered: a rare presentation with gliomatosis cerebri growth pattern and progression toward midline

Louis DN, Perry A, Reifenberger G et al (2016) The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 131:803–820

Article  PubMed  Google Scholar 

Louis DN, Perry A, Wesseling P et al (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro Oncol 23:1231–1251

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fujioka Y, Hata N, Hatae R et al (2020) A case of diffuse midline glioma, H3 K27M mutant mimicking a hemispheric malignant glioma in an elderly patient. Neuropathology 40:99–103

Article  CAS  PubMed  Google Scholar 

Bennett J, Erker C, Lafay-Cousin L et al (2020) Canadian pediatric neuro-oncology standards of practice. Front Oncol 10:593192

Article  PubMed  PubMed Central  Google Scholar 

Koschmann C, Al-Holou WN, Alonso MM et al (2024) A road map for the treatment of pediatric diffuse midline glioma. Cancer Cell 42:1–5

Article  CAS  PubMed  Google Scholar 

Aldape K, Brindle KM, Chesler L et al (2019) Challenges to curing primary brain tumours. Nat Rev Clin Oncol 16:509–520

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arrillaga-Romany I, Gardner SL, Odia Y et al (2024) ONC201 (dordaviprone) in recurrent H3 K27M-mutant diffuse midline glioma. J Clin Oncol 42:1542–1552

Article  CAS  PubMed  Google Scholar 

Stupp R, Mason WP, van den Bent MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987–996

Article  CAS  PubMed  Google Scholar 

Wang Y, Feng LL, Ji PG et al (2020) Clinical features and molecular markers on diffuse midline gliomas with H3K27M mutations: a 43 cases retrospective cohort study. Front Oncol 10:602553

Article  PubMed  Google Scholar 

Qiu T, Chanchotisatien A, Qin Z et al (2020) Imaging characteristics of adult H3 K27M-mutant gliomas. J Neurosurg 133:1662–1670

Article  CAS  PubMed  Google Scholar 

La Rocca G, Sabatino G, Altieri R et al (2019) Significance of H3K27M mutation in “nonmidline” high-grade gliomas of cerebral hemispheres. World Neurosurg 131:174–176

Article  PubMed  Google Scholar 

Wang L, Li Z, Zhang M et al (2018) H3 K27M-mutant diffuse midline gliomas in different anatomical locations. Hum Pathol 78:89–96

Article  CAS  PubMed  Google Scholar 

Badaloni ME, Johnson AR, Argañaraz R et al (2023) Intratumoral catheter placement in pediatric patients with diffuse midline gliomas. Childs Nerv Syst 39:2065–2070

Article  PubMed  Google Scholar 

Nakano Y, Yamasaki K, Satomi K et al (2020) A case of pediatric gliomatosis cerebri harboring H3F3A K27 mutation. Pediatr Blood Cancer 67:e28270

Article  CAS  PubMed  Google Scholar 

Yekula A, Gupta M, Coley N et al (2020) Adult H3K27M-mutant diffuse midline glioma with gliomatosis cerebri growth pattern: case report and review of the literature. Int J Surg Case Rep 68:124–128

Article  PubMed  PubMed Central  Google Scholar 

Broniscer A, Chamdine O, Hwang S et al (2016) Gliomatosis cerebri in children shares molecular characteristics with other pediatric gliomas. Acta Neuropathol 131:299–307

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guidara S, Seyve A, Poncet D et al (2024) Characteristics of H3K27M-mutant diffuse gliomas with a non-midline location. J Neurooncol 169:391–398

Article  CAS  PubMed  Google Scholar 

Williams EA, Brastianos PK, Wakimoto H et al (2023) A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4. Acta Neuropathol 146:515–525

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu I, Jiang L, Samuelsson ER et al (2022) The landscape of tumor cell states and spatial organization in H3–K27M mutant diffuse midline glioma across age and location. Nat Genet 54:1881–1894

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mackay A, Burford A, Carvalho D et al (2017) Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma. Cancer Cell 32:520-537.e525

Article  CAS  PubMed  PubMed Central  Google Scholar 

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