Exploring the impact of ADIPOQ gene variants on plasma adiponectin levels and oxidative stress in type 2 diabetes mellitus and diabetic nephropathy in South Indian population: a case–control study

Farmaki P, Damaskos C, Garmpis N, et al. Complications of the type 2 diabetes mellitus. Curr Cardiol Rev. 2020;16(4):249–51.

PubMed  PubMed Central  Google Scholar 

Sagoo MK, Gnudi L. Diabetic nephropathy: an overview. Methods Mol Biol. 2020;2067:3–7.

CAS  PubMed  Google Scholar 

Khoramipour K, Chamari K, Hekmatikar AA, et al. Adiponectin: structure, physiological functions, role in diseases, and effects of nutrition. Nutrients. 2021;13(4):1180.

CAS  PubMed  PubMed Central  Google Scholar 

Fumeron F, Aubert R, Siddiq A, et al. Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period: the epidemiologic data on the insulin resistance syndrome prospective study. Diabetes. 2004;53:1150–7.

CAS  PubMed  Google Scholar 

Przybyciński J, Dziedziejko V, Puchałowicz K, Domański L, Pawlik A. Adiponectin in chronic kidney disease. Int J Mol Sci. 2020;21(24):9375.

PubMed  PubMed Central  Google Scholar 

Howlader M, Sultana MI, Akter F, Hossain MM. Adiponectin gene polymorphisms associated with diabetes mellitus: a descriptive review. Heliyon. 2021;7(8): e07851.

CAS  PubMed  PubMed Central  Google Scholar 

Maleki M, Karajibani M, Sarvani M, et al. Correlation between adiponectin rs2241766 and rs266729 polymorphisms and risk of papillary thyroid cancer. Mol Biol Res Commun. 2022;11(3):113–8.

CAS  PubMed  PubMed Central  Google Scholar 

Hussain MK, Deli FA, Algenabi AHA, et al. Adiponectin gene polymorphisms as a predictor for development of type 2 diabetes mellitus in Iraqi population. Gene. 2018;662:118–22.

CAS  PubMed  Google Scholar 

Hu FB, Doria A, Li T, et al. Genetic variation at the adiponectin locus and risk of type 2 diabetes in women. Diabetes. 2004;53:209–13.

CAS  PubMed  Google Scholar 

Choe EY, Wang HJ, Kwon O, et al. Variants of the adiponectin gene and diabetic microvascular complications in patients with type 2 diabetes. Metabolism. 2013;62(5):677–85.

CAS  PubMed  Google Scholar 

Chung HF, Long KZ, Hsu CC, et al. Adiponectin gene (ADIPOQ) polymorphisms correlate with the progression of nephropathy in Taiwanese male patients with type 2 diabetes. Diabetes Res Clin Pract. 2014;105(2):261–70.

CAS  PubMed  Google Scholar 

Karimi H, Nezhadali M, Hedayati M. Association between adiponectin rs17300539 and rs266729 gene polymorphisms with serum adiponectin level in an Iranian diabetic/pre diabetic population. Endocr Regul. 2018;52(4):176–84.

PubMed  Google Scholar 

Mtiraoui N, Ezzidi I, Turki A, et al. Single-nucleotide polymorphisms and haplotypes in the adiponectin gene contribute to the genetic risk for type 2 diabetes in Tunisian Arabs. Diabetes Res Clin Pract. 2012;97(2):290–7.

CAS  PubMed  Google Scholar 

Nazir N, Siddiqui K, Al-Qasim S, et al. Meta-analysis of diabetic nephropathy associated genetic variants in inflammation and angiogenesis involved in different biochemical pathways. BMC Med Genet. 2014;15:103.

PubMed  PubMed Central  Google Scholar 

Jortay J, Senou M, Abou-Samra M, et al. Adiponectin and skeletal muscle: pathophysiological implications in metabolic stress. Am J Pathol. 2012;181(1):245–56.

CAS  PubMed  Google Scholar 

Essick EE, Wilson RM, Pimentel DR, et al. Adiponectin modulates oxidative stress-induced autophagy in cardiomyocytes. PLoS ONE. 2013;8(7): e68697.

CAS  PubMed  PubMed Central  Google Scholar 

Sobha SP, Kesavarao EK. Susceptibility of glutathione-S-transferase polymorphism to CVD development in type 2 diabetes mellitus – a review. Endocr Metab Immune Disord Drug Targets. 2022;22(2):225–34.

CAS  PubMed  Google Scholar 

Gross JL, De Azevedo MJ, Silverio SP, et al. Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care. 2005;28(1):164–76.

PubMed  Google Scholar 

Rojas-Sole C, Lillo Moya J, Rodrigo R. Oxidative stress biomarkers in human health and disease. In: Saso L, Giuffre A, Valacchi G, Maccarrone M, editors. Modulation of Oxidative stress. Biochemical, physiology and pharmacological aspects. Academic Press; 2023. p. 97–112.

Google Scholar 

Sobha SP, Kesavarao EK. Progonostic effect of GSTM1/GSTT1 polymorphism in determining cardiovascular diseases risk among type 2 diabetes patients in south Indian population. Mol Bio Rep. 2023;50(8):6415–23.

CAS  Google Scholar 

Potapov VA, Chistiakov DA, Dubinina A, et al. Adiponectin and adiponectin receptor gene variants in relation to type 2 diabetes and insulin resistance-related phenotypes. Rev Diabet Stud. 2008;5(1):28–37.

PubMed  PubMed Central  Google Scholar 

Ukkola O, Santaniemi M, Rankinen T, et al. Adiponectin polymorphisms, adiposity and insulin metabolism: HERITAGE family study and Oulu diabetic study. Ann Med. 2005;37:141–50.

CAS  PubMed  Google Scholar 

Vasseur F, Helbecque N, Dina C, et al. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. Hum Mol Genet. 2002;11(21):2607–14.

CAS  PubMed  Google Scholar 

Chiodini BD, Specchia C, Gori F, et al. Adiponectin gene polymorphisms and their effect on the risk of myocardial infarction and type 2 diabetes: an association study in an Italian population. Ther Adv Cardiovasc Dis. 2010;4:223–30.

CAS  PubMed  Google Scholar 

Han LY, Wu QH, Jiao ML, et al. Associations between single-nucleotide polymorphisms (+45T>G, +276G>T, −11377C>G, −11391G>A) of adiponectin gene and type 2 diabetes mellitus: a systematic review and meta-analysis. Diabetologia. 2011;54:2303–14.

CAS  PubMed  Google Scholar 

Komura N, Kihara S, Sonoda M, et al. Increment and impairment of adiponectin in renal failure. Cardiovasc Res. 2010;86(3):471–7.

CAS  PubMed  Google Scholar 

Sakaue TA, Fujishima Y, Fukushima Y, et al. Adiponectin accumulation in the retinal vascular endothelium and its possible role in preventing early diabetic microvascular damage. Sci Rep. 2022;12(1):4159.

CAS  PubMed  PubMed Central  Google Scholar 

Tsugawa-Shimizu Y, Fujishima Y, Kita S, et al. Increased vascular permeability and severe renal tubular damage after ischemia-reperfusion injury in mice lacking adiponectin or T-cadherin. Am J Physiol Endocrinol Metab. 2021;320(2):E179–90.

CAS  PubMed  Google Scholar 

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