Mechanistic insights into interaction facilitating UV-induced DNA damage repair in

Huang B, Mengersen A, Lee VD (1988) Molecular cloning of cDNA for caltractin, a basal body-associated Ca2+-binding protein: homology in its protein sequence with calmodulin and the yeast CDC31 gene product. J Cell Biol 107:133–40. https://doi.org/10.1083/jcb.107.1.133

Article  CAS  PubMed  Google Scholar 

Errabolu R, Sanders MA, Salisbury JL (1994) Cloning of a cDNA encoding human centrin, an EF-hand protein of centrosomes and mitotic spindle poles. J Cell Sci 107(Pt 1):9–16. https://doi.org/10.1242/jcs.107.1.9

Article  CAS  PubMed  Google Scholar 

Salisbury JL (1995) Centrin, centrosomes, and mitotic spindle poles. Curr Opin Cell Biol 7:39–45. https://doi.org/10.1016/0955-0674(95)80043-3

Article  CAS  PubMed  Google Scholar 

Gavet O, Alvarez C, Gaspar P, Bornens M (2003) Centrin4p, a novel mammalian centrin specifically expressed in ciliated cells. Mol Biol Cell 14:1818–34. https://doi.org/10.1091/mbc.e02-11-0709

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mahajan B, Selvapandiyan A, Gerald NJ, Majam V, Zheng H, Wickramarachchi T, Tiwari J, Fujioka H, Moch JK, Kumar N, Aravind L, Nakhasi HL, Kumar S (2008) Centrins, cell cycle regulation proteins in human malaria parasite Plasmodium falciparum. J Biol Chem 283:31871–83. https://doi.org/10.1074/jbc.M800028200

Article  CAS  PubMed  Google Scholar 

Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Bohme U, Hannick L, Aslett MA, Shallom J, Marcello L, Hou L, Wickstead B, Alsmark UC, Arrowsmith C, Atkin RJ, Barron AJ, Bringaud F, Brooks K, Carrington M, Cherevach I, Chillingworth TJ, Churcher C, Clark LN, Corton CH, Cronin A, Davies RM, Doggett J, Djikeng A, Feldblyum T, Field MC, Fraser A, Goodhead I, Hance Z, Harper D, Harris BR, Hauser H, Hostetler J, Ivens A, Jagels K, Johnson D, Johnson J, Jones K, Kerhornou AX, Koo H, Larke N, Landfear S, Larkin C, Leech V, Line A, Lord A, Macleod A, Mooney PJ, Moule S, Martin DM, Morgan GW, Mungall K, Norbertczak H, Ormond D, Pai G, Peacock CS, Peterson J, Quail MA, Rabbinowitsch E, Rajandream MA, Reitter C, Salzberg SL, Sanders M, Schobel S, Sharp S, Simmonds M, Simpson AJ, Tallon L, Turner CM, Tait A, Tivey AR, Van Aken S, Walker D, Wanless D, Wang S, White B, White O, Whitehead S, Woodward J, Wortman J, Adams MD, Embley TM, Gull K, Ullu E, Barry JD, Fairlamb AH, Opperdoes F, Barrell BG, Donelson JE, Hall N, Fraser CM, Melville SE, El-Sayed NM (2005) The genome of the African trypanosome Trypanosoma brucei. Science 309:416–22. https://doi.org/10.1126/science.1112642

Article  CAS  PubMed  Google Scholar 

Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G, Berriman M, Sisk E, Rajandream MA, Adlem E, Aert R, Anupama A, Apostolou Z, Attipoe P, Bason N, Bauser C, Beck A, Beverley SM, Bianchettin G, Borzym K, Bothe G, Bruschi CV, Collins M, Cadag E, Ciarloni L, Clayton C, Coulson RM, Cronin A, Cruz AK, Davies RM, De Gaudenzi J, Dobson DE, Duesterhoeft A, Fazelina G, Fosker N, Frasch AC, Fraser A, Fuchs M, Gabel C, Goble A, Goffeau A, Harris D, Hertz-Fowler C, Hilbert H, Horn D, Huang Y, Klages S, Knights A, Kube M, Larke N, Litvin L, Lord A, Louie T, Marra M, Masuy D, Matthews K, Michaeli S, Mottram JC, Muller-Auer S, Munden H, Nelson S, Norbertczak H, Oliver K, O’Neil S, Pentony M, Pohl TM, Price C, Purnelle B, Quail MA, Rabbinowitsch E, Reinhardt R, Rieger M, Rinta J, Robben J, Robertson L, Ruiz JC, Rutter S, Saunders D, Schafer M, Schein J, Schwartz DC, Seeger K, Seyler A, Sharp S, Shin H, Sivam D, Squares R, Squares S, Tosato V, Vogt C, Volckaert G, Wambutt R, Warren T, Wedler H, Woodward J, Zhou S, Zimmermann W, Smith DF, Blackwell JM, Stuart KD, Barrell B, Myler PJ (2005) The genome of the kinetoplastid parasite, Leishmania major. Science 309:436–42. https://doi.org/10.1126/science.1112680

Article  PubMed  PubMed Central  Google Scholar 

Selvapandiyan A, Duncan R, Debrabant A, Bertholet S, Sreenivas G, Negi NS, Salotra P, Nakhasi HL (2001) Expression of a mutant form of Leishmania donovani centrin reduces the growth of the parasite. J Biol Chem 276:43253–61. https://doi.org/10.1074/jbc.M106806200

Article  CAS  PubMed  Google Scholar 

Selvapandiyan A, Kumar P, Morris JC, Salisbury JL, Wang CC, Nakhasi HL (2007) Centrin1 is required for organelle segregation and cytokinesis in Trypanosoma brucei. Mol Biol Cell 18:3290–301. https://doi.org/10.1091/mbc.e07-01-0022

Article  CAS  PubMed  PubMed Central  Google Scholar 

Selvapandiyan A, Croft SL, Rijal S, Nakhasi HL, Ganguly NK (2019) Innovations for the elimination and control of visceral leishmaniasis. PLoS Negl Trop Dis 13:e0007616. https://doi.org/10.1371/journal.pntd.0007616

Article  PubMed  PubMed Central  Google Scholar 

Selvapandiyan A, Debrabant A, Duncan R, Muller J, Salotra P, Sreenivas G, Salisbury JL, Nakhasi HL (2004) Centrin gene disruption impairs stage-specific basal body duplication and cell cycle progression in Leishmania. J Biol Chem 279:25703–10. https://doi.org/10.1074/jbc.M402794200

Article  CAS  PubMed  Google Scholar 

Selvapandiyan A, Puri N, Kumar P, Alam A, Ehtesham NZ, Griffin G, Hasnain SE (2023) Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases. FEMS Microbiol Rev 47:fuac041. https://doi.org/10.1093/femsre/fuac041

Article  CAS  PubMed  Google Scholar 

Selvapandiyan A, Dey R, Nylen S, Duncan R, Sacks D, Nakhasi HL (2009) Intracellular replication-deficient Leishmania donovani induces long lasting protective immunity against visceral leishmaniasis. J Immunol 183:1813–20. https://doi.org/10.4049/jimmunol.0900276

Article  CAS  PubMed  Google Scholar 

Bhattacharya P, Dey R, Dagur PK, Joshi AB, Ismail N, Gannavaram S, Debrabant A, Akue AD, KuKuruga MA, Selvapandiyan A, McCoy JP Jr, Nakhasi HL (2016) Live attenuated Leishmania donovani Centrin knock out parasites generate non-inferior protective immune response in aged mice against visceral Leishmaniasis. PLoS Negl Trop Dis 10:e0004963. https://doi.org/10.1371/journal.pntd.0004963

Article  CAS  PubMed  PubMed Central  Google Scholar 

Avishek K, Kaushal H, Gannavaram S, Dey R, Selvapandiyan A, Ramesh V, Negi NS, Dubey US, Nakhasi HL, Salotra P (2016) Gene deleted live attenuated Leishmania vaccine candidates against visceral leishmaniasis elicit pro-inflammatory cytokines response in human PBMCs. Sci Rep 6:33059. https://doi.org/10.1038/srep33059

Article  CAS  PubMed  PubMed Central  Google Scholar 

Avishek K, Beg MA, Vats K, Singh AK, Dey R, Singh KP, Singh RK, Gannavaram S, Ramesh V, Mulla MSA, Bhatnagar U, Singh S, Nakhasi HL, Salotra P, Selvapandiyan A (2024) Manufacturing and preclinical toxicity of GLP grade gene deleted attenuated Leishmania donovani parasite vaccine. Sci Rep 14:14636. https://doi.org/10.1038/s41598-024-64592-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Paoletti A, Moudjou M, Paintrand M, Salisbury JL, Bornens M (1996) Most of centrin in animal cells is not centrosome-associated and centrosomal centrin is confined to the distal lumen of centrioles. J Cell Sci 109(Pt 13):3089–102. https://doi.org/10.1242/jcs.109.13.3089

Article  CAS  PubMed  Google Scholar 

Riedl T, Hanaoka F, Egly JM (2003) The comings and goings of nucleotide excision repair factors on damaged DNA. EMBO J 22:5293–303. https://doi.org/10.1093/emboj/cdg489

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sugasawa K, Ng JM, Masutani C, Iwai S, van der Spek PJ, Eker AP, Hanaoka F, Bootsma D, Hoeijmakers JH (1998) Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell 2:223–32. https://doi.org/10.1016/s1097-2765(00)80132-x

Article  CAS  PubMed  Google Scholar 

Volker M, Mone MJ, Karmakar P, van Hoffen A, Schul W, Vermeulen W, Hoeijmakers JH, van Driel R, van Zeeland AA, Mullenders LH (2001) Sequential assembly of the nucleotide excision repair factors in vivo. Mol Cell 8:213–24. https://doi.org/10.1016/s1097-2765(01)00281-7

Article  CAS  PubMed  Google Scholar 

Nishi R, Okuda Y, Watanabe E, Mori T, Iwai S, Masutani C, Sugasawa K, Hanaoka F (2005) Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein. Mol Cell Biol 25:5664–74. https://doi.org/10.1128/MCB.25.13.5664-5674.2005

Article  CAS  PubMed  PubMed Central  Google Scholar 

Araki M, Masutani C, Takemura M, Uchida A, Sugasawa K, Kondoh J, Ohkuma Y, Hanaoka F (2001) Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair. J Biol Chem 276:18665–72. https://doi.org/10.1074/jbc.M100855200

Article  CAS  PubMed  Google Scholar 

Lopez-Camarillo C, Lopez-Casamichana M, Weber C, Guillen N, Orozco E, Marchat LA (2009) DNA repair mechanisms in eukaryotes: Special focus in Entamoeba histolytica and related protozoan parasites. Infect Genet Evol 9:1051–6. https://doi.org/10.1016/j.meegid.2009.06.024

Article  CAS  PubMed 

Comments (0)

No login
gif