We thank Dr Wang et al for their detailed and constructive comments1 about our recent publication titled ‘Absorbable gelatin compressed sponge (Gelfoam) embolization of distal external carotid artery branches in intra-arterial chemotherapy for retinoblastoma’.2 We greatly appreciate your insights, which have provided us with an opportunity to clarify certain points of our study and open up discussion on important aspects to consider in future work.

We would like to address each of the concerns raised:

Sample size and generalizability: We agree that the sample size of our cohort (11 patients and 14 infusions of intra-arterial chemotherapy using Gelfoam pledgets) limits the generalizability of our findings. However, our primary aim was to describe this innovative and very easy technique so that it could be performed …