FATP1-mediated fatty acid uptake in renal tubular cells as a countermeasure for hypothermia

Grapatsas K, Leivaditis V, Panagiotopoulos I, Spiliotopoulos K, Koletsis E, Dahm M, Kosmidis C, Laskou S, Zarogoulidis P, Katsaounis A et al (2018) Deep accidental hypothermia accompanied with cardiac arrest after alcohol and drug poisoning treated with extracorporeal life support. Respir Med Case Rep 25:66–67. https://doi.org/10.1016/j.rmcr.2018.06.011

Article  PubMed  PubMed Central  Google Scholar 

Gordon L, Paal P, Ellerton JA, Brugger H, Peek GJ, Zafren K (2015) Delayed and intermittent CPR for severe accidental hypothermia. Resuscitation 90:46–49. https://doi.org/10.1016/j.resuscitation.2015.02.017

Article  PubMed  Google Scholar 

Avellanas ML, Ricart A, Botella J, Mengelle F, Soteras I, Veres T, Vidal M (2012) Management of severe accidental hypothermia. Med Intensiva 36:200–212. https://doi.org/10.1016/j.medin.2011.12.005

Article  PubMed  CAS  Google Scholar 

Oshiro K, Tanioka Y, Schweizer J, Zafren K, Brugger H, Paal P (2022) Prevention of hypothermia in the aftermath of natural disasters in areas at risk of avalanches, earthquakes, tsunamis and floods. Int J Environ Res Public Health 19:1098. https://doi.org/10.3390/ijerph19031098

Article  PubMed  PubMed Central  Google Scholar 

Braun T, Mosinger B (1958) Effect of hypothermia on death by starvation. Nature 181:968. https://doi.org/10.1038/181968a0

Article  PubMed  CAS  Google Scholar 

Petrone P, Asensio JA, Marini CP (2014) Management of accidental hypothermia and cold injury. Curr Probl Surg 51:417–431. https://doi.org/10.1067/j.cpsurg.2014.07.004

Article  PubMed  Google Scholar 

Takauji S, Hayakawa M, Yamada D, Tian T, Minowa K, Inoue A, Fujimoto Y, Isokawa S, Miura N, Endo T et al (2023) Outcome of extracorporeal membrane oxygenation use in severe accidental hypothermia with cardiac arrest and circulatory instability: a multicentre, prospective, observational study in Japan (ICE-CRASH study). Resuscitation 182:109663. https://doi.org/10.1016/j.resuscitation.2022.12.001

Article  PubMed  Google Scholar 

Haverkamp FJC, Giesbrecht GG, Tan E (2018) The prehospital management of hypothermia - an up-to-date overview. Injury 49:149–164. https://doi.org/10.1016/j.injury.2017.11.001

Article  PubMed  Google Scholar 

Polderman KH (2012) Hypothermia and coagulation. Crit Care 16:A20–A20. https://doi.org/10.1186/cc11278

Article  PubMed Central  Google Scholar 

Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Gasche Y, Hassager C, Horn J, Hovdenes J, Kjaergaard J, Kuiper M et al (2013) Targeted temperature management at 33°C versus 36°C after cardiac arrest. N Engl J Med 369:2197–2206. https://doi.org/10.1056/NEJMoa1310519

Article  PubMed  CAS  Google Scholar 

Cortez E, Panchal AR, Davis J, Zeeb P, Keseg DP (2015) Clinical outcomes in cardiac arrest patients following prehospital treatment with therapeutic hypothermia. Prehosp Disaster Med 30:452–456. https://doi.org/10.1017/s1049023x15004987

Article  PubMed  Google Scholar 

Fritz HG (2014) Mild therapeutic hypothermia in cardiac arrest. Dtsch Med Wochenschr (1946) 139:141–146. https://doi.org/10.1055/s-0033-1359917

Lin JJ, Lin CY, Hsia SH, Wang HS, Chiang MC, Lin KL (2018) 72-hour therapeutic hypothermia improves neurological outcomes in paediatric asphyxial out-of-hospital cardiac arrest-an exploratory investigation. Resuscitation. https://doi.org/10.1016/j.resuscitation.2018.08.019

Article  PubMed  Google Scholar 

Ou J, Ball JM, Luan Y, Zhao T, Miyagishima KJ, Xu Y, Zhou H, Chen J, Merriman DK, Xie Z et al (2018) iPSCs from a hibernator provide a platform for studying cold adaptation and its potential medical applications. Cell 173:851–863.e816. https://doi.org/10.1016/j.cell.2018.03.010

Article  PubMed  PubMed Central  CAS  Google Scholar 

Horioka K, Tanaka H, Okaba K, Yamada S, Hayakawa A, Ishii N, Motomura A, Inoue H, Takauji S, Isozaki S et al (2023) Bioprotective role of platelet-derived microvesicles in hypothermia: insight into the differential characteristics of peripheral and splenic platelets. Thromb Res 223:155–167. https://doi.org/10.1016/j.thromres.2023.01.006

Article  PubMed  CAS  Google Scholar 

Kist M, Vucic D (2021) Cell death pathways: intricate connections and disease implications. The EMBO Journal 40:e106700. https://doi.org/10.15252/embj.2020106700

Article  PubMed  PubMed Central  CAS  Google Scholar 

Palmiere C, Bardy D, Letovanec I, Mangin P, Augsburger M, Ventura F, Iglesias K, Werner D (2013) Biochemical markers of fatal hypothermia. Forensic Sci Int 226:54–61. https://doi.org/10.1016/j.forsciint.2012.12.007

Article  PubMed  CAS  Google Scholar 

Teresiński G, Buszewicz G, Madro R (2002) The influence of ethanol on the level of ketone bodies in hypothermia. Forensic Sci Int 127:88–96. https://doi.org/10.1016/s0379-0738(02)00106-8

Article  PubMed  Google Scholar 

Poursharifi P, Attané C, Mugabo Y, Al-Mass A, Ghosh A, Schmitt C, Zhao S, Guida J, Lussier R, Erb H et al (2020) Adipose ABHD6 regulates tolerance to cold and thermogenic programs. JCI Insight 5:e140294. https://doi.org/10.1172/jci.insight.140294

Article  PubMed  PubMed Central  Google Scholar 

Zhang M, Wang N, Guo XS, Wang LL, Wang PF, Cao ZP, Zhang FY, Wang ZW, Guan DW, Zhao R (2022) Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia. International journal of legal medicine. https://doi.org/10.1007/s00414-022-02897-9

Article  PubMed  Google Scholar 

Preuss J, Dettmeyer R, Lignitz E, Madea B (2004) Fatty degeneration in renal tubule epithelium in accidental hypothermia victims. Forensic Sci Int 141:131–135. https://doi.org/10.1016/j.forsciint.2003.12.017

Article  PubMed  CAS  Google Scholar 

Tekin B, Righi F, Quinton R (2022) Renal tubular epithelial subnuclear vacuolization in hypothermia and diabetic ketoacidosis-a retrospective autopsy study. Am J Forensic Med Pathol 43:23–27. https://doi.org/10.1097/paf.0000000000000692

Article  PubMed  Google Scholar 

Bignon Y, Wigger L, Ansermet C, Weger BD, Lagarrigue S, Centeno G, Durussel F, Götz L, Ibberson M, Pradervand S et al (2023) Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock. The Journal of clinical investigation 133:e167133. https://doi.org/10.1172/JCI167133

Article  PubMed  PubMed Central  CAS  Google Scholar 

Nguyen TB, Louie SM, Daniele JR, Tran Q, Dillin A, Zoncu R, Nomura DK, Olzmann JA (2017) DGAT1-dependent lipid droplet biogenesis protects mitochondrial function during starvation-induced autophagy. Dev Cell 42:9–21.e25. https://doi.org/10.1016/j.devcel.2017.06.003

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bergman H-M, Lindfors L, Palm F, Kihlberg J, Lanekoff I (2019) Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging. Anal Bioanal Chem 411:2809–2816. https://doi.org/10.1007/s00216-019-01721-5

Article  PubMed  PubMed Central  CAS  Google Scholar 

Jouandin P, Marelja Z, Shih YH, Parkhitko AA, Dambowsky M, Asara JM, Nemazanyy I, Dibble CC, Simons M, Perrimon N (2022) Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting. Science 375:eabc4203. https://doi.org/10.1126/science.abc4203

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gewin LS (2021) Sugar or fat? Renal tubular metabolism reviewed in health and disease. Nutrients 13:1580

Article  PubMed  PubMed Central  CAS  Google Scholar 

Mitrofanova A, Merscher S, Fornoni A (2023) Kidney lipid dysmetabolism and lipid droplet accumulation in chronic kidney disease. Nat Rev Nephrol 19:629–645. https://doi.org/10.1038/s41581-023-00741-w

Article  PubMed  CAS  Google Scholar 

Comments (0)

No login
gif