COVID-19 prior to hematopoietic stem cell transplantation increases the risk of acute graft-versus-host disease but does not affect overall mortality

Randi BA, Higashino HR, Silva VPD, Xavier EM, Rocha V, Costa SF. COVID-19 in hematopoietic stem-cell transplant recipients: A systematic review and meta-analysis of clinical characteristics and outcomes. Rev Med Virol. 2023;33:e2483.

Piñana JL, Pérez A, Chorão P, Guerreiro M, García-Cadenas I, Solano C, et al. Respiratory virus infections after allogeneic stem cell transplantation: Current understanding, knowledge gaps, and recent advances. Transpl Infect Dis. 2023;25:e14117.

Article  PubMed  Google Scholar 

Oltolini C, Travi G, Mikulska M. The impact of prior COVID-19 on non-infectious endothelial complications following allogeneic hematopoietic stem cell transplantation. Clin Infect Dis. 2024:ciae307. https://doi.org/10.1093/cid/ciae307. Online ahead of print.

Nimgaonkar I, Yoke LH, Roychoudhury P, Flaherty PW, Oshima MU, Weixler A, et al. Outcomes in Hematopoietic Cell Transplant and Chimeric Antigen Receptor T-Cell Therapy Recipients With Pre-Cellular Therapy SARS-CoV-2 Infection. Clin Infect Dis. 2024;79:86–95.

Article  PubMed  Google Scholar 

Shah N, Dahi PB, Ponce DM, Sauter CS, Shaffer BC, Chung DJ, et al. Hematopoietic Cell Transplantation is Feasible in Patients with Prior COVID-19 Infection. Transplant Cell Ther. 2022;28:55.e1–.e5.

Article  CAS  PubMed  Google Scholar 

Marinos A, Ramdial J, Khawaja F, Saliba RM, Shigle TL, Alousi AM, et al. Hematopoietic cell transplantation can be safely performed after COVID-19. Bone Marrow Transplant. 2023;58:1410–2.

Article  PubMed  Google Scholar 

Oltolini C, Acerbis A, Orofino G, Racca S, Noviello M, Dispinseri S, et al. Case Report: Favorable outcome of allogeneic hematopoietic stem cell transplantation in SARSCoV2 positive recipient, risk-benefit balance between infection and leukemia. Front Immunol. 2023;14:1184956.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pourhassan H, La Rosa C, Chiuppesi F, Puing A, Aldoss I, Park Y, et al. Successful outcome of pre-engraftment COVID-19 in an HCT patient: impact of targeted therapies and cellular immunity. Blood Adv. 2022;6:1645–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brasil. Ministério da Saúde. Fundação Oswaldo Cruz. Rede Genômica Fiocruz. GISAID: linhagens em circulação: SARS-CoV-2. 2025. Available from: https://www.genomahcov.fiocruz.br/.

Iacobelli S. Committee ES. Suggestions on the use of statistical methodologies in studies of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant. 2013;48:S1–37.

Article  PubMed  Google Scholar 

Cesaro S, Mikulska M, Hirsch HH, Styczynski J, Meylan S, Cordonnier C, et al. Update of recommendations for the management of COVID-19 in patients with haematological malignancies, haematopoietic cell transplantation and CAR T therapy, from the 2022 European Conference on Infections in Leukaemia (ECIL 9). Leukemia. 2023;37:1933–8.

Article  PubMed  PubMed Central  Google Scholar 

Nimgaonkar I, Flaherty PW, Oshima MU, Hill JA. Acute Endothelial Complications Post-Allogeneic Hematopoietic Cell Transplant in Patients with Pre-Cellular Therapy SARS-CoV-2 Infection. Clin Infect Dis. 2024:ciae310. https://doi.org/10.1093/cid/ciae310. Online ahead of print.

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