World Health Organization (WHO). Guidelines for efficacy testing of mosquito repellents for human skin. World Health Organization; 2009. No. WHO/HTM/NTD/WHOPES/2009.4.

Torto B, Tchouassi DP. Chemical ecology and management of dengue vectors. Ann Rev Entomol. 2024;69(1):159–82.

Article  CAS  Google Scholar 

Diéguez L, Pino R, Andrés J, Hernández A, Alarcón-Elbal PM, San Martín JL. Actualización De Los hábitats larvarios de Aedes aegypti (Diptera: Culicidae) en Camagüey, Cuba. Revista De Biología Trop. 2016;64(4):1487–93.

Google Scholar 

Gloria-Soria A, Ayala D, Bheecarry A, Calderon-Arguedas O, Chadee DD, et al. Global genetic diversity of Aedes aegypti. Mol Ecol. 2016;25:5377–95.

Article  PubMed  PubMed Central  Google Scholar 

Ministerio de Salud de la Nación Argentina. Boletín Epidemiológico Nac. 2024; 42 Nro 727.

Vezzani D, Carbajo AE. Aedes aegypti, Aedes albopictus, and dengue in Argentina: current knowledge and future directions. Memorias do Instituto Oswaldo Cruz, 2008; 103, 66–74.

Rubio A, Cardo MV, Vezzani D, Carbajo AE. Aedes aegypti spreading in South America: new coldest and southernmost records. Mem Inst Oswaldo Cruz. 2020;115:e190496.

Article  PubMed  PubMed Central  Google Scholar 

Uc-Puc V, Herrera-Bojórquez J, Carmona-Carballo C, Che-Mendoza A, Medina-Barreiro A, Chablé-Santos J, Arredondo-Jiménez JI, Flores-Suárez AE, Manrique-Saide P. Effectiveness of commercial repellents against Aedes aegypti (L.) in Yucatan, México. Salud pública De México. 2016; 58(4): 472–5.

Paluch G, Bartholomay L, Coats J. Mosquito repellents: a review of chemical structure diversity and olfaction. Pest Manag Sci. 2010;66(9):925–35.

Article  PubMed  CAS  Google Scholar 

Roitberg BD, Friend WG. A general theory for host seeking decisions in mosquitoes. Bull Math Biol. 1992;54:401–12.

Article  PubMed  CAS  Google Scholar 

Chandel A, DeBeaubien NA, Ganguly A, Meyerhof GT, Krumholz AA, Liu J, Salgado VL. Montell, C. Thermal infrared directs host-seeking behaviour in Aedes aegypti mosquitoes. Nature. 2024;633(8030):615–23.

Curran AM, Rabin SI, Prada PA, Furton KG. Comparison of the volatile organic compounds present in human odor using SPMEGC/MS. J Chem Ecol. 2005;31:1607–19.

Article  PubMed  CAS  Google Scholar 

Bernier UR, Kline DL, Posey KH. Human emanations and related natural compounds that inhibit mosquito host-finding abilities, in Insect Repellents: Principles, Methods, and Uses, ed. by Debboun M, Frances SP and Strickman D. CRC Press, London, UK. 2007; pp. 31–46.

Duvall LB. Mosquito host-seeking regulation: targets for behavioral control. Trends Parasitol. 2019;35:9. https://doi.org/10.1016/j.pt.2019.06.010.

Article  Google Scholar 

Xue RD, Ali A, Day JF. Commercially available insect repellents and criteria for their use. In: Debboun M, Frances SP, & Strickman D, editors. Insect repellents handbook. Chapter 25. 2nd ed. CRC Press; 2007.

Luker HA. A critical review of current laboratory methods used to evaluate mosquito repellents. Front Insect Sci. 2024;4:1320138.

Article  PubMed  PubMed Central  Google Scholar 

Yang P, Ma Y. Repellent effect of plant essential oils against Aedes albopictus. J Vector Ecol. 2005;30(2):231.

PubMed  Google Scholar 

Brown M, Hebert AA. Insect repellents: an overview. J Am Acad Dermatol. 1997;36(2):243–9.

Article  PubMed  CAS  Google Scholar 

Fradin MS, Day JF. Comparative efficacy of insect repellents against mosquito bites. N Engl J Med. 2002;347(1):13–8.

Article  PubMed  CAS  Google Scholar 

Amer A, Mehlhorn H. Larvicidal effects of various essential oils against Aedes, Anopheles, and Culex larvae (Diptera, Culicidae). Parasitol Res. 2006;99(4):466–72.

Article  PubMed  Google Scholar 

Gomes J, Bankuti R, Moraes C, Seo E. Critical analysis of mosquito repellents formulation in the Brazilian market. Int J Dev Res. 2022;12:55129–31.

Fei B, Xin JH. N, N-diethyl-m-toluamide–containing microcapsules for bio-cloth finishing. Am J Trop Med Hyg. 2007;77(1):52–7.

Article  PubMed  CAS  Google Scholar 

Administración Nacional de Medicamentos. Alimentos y Tecnología Médica (ANMAT). Inscripción de repelentes de uso externo en humanos. Access: 07/2024. https://back.argentina.gob.ar/anmat/regulados/cosmeticos/inscripcion-de-repelentes-de-uso-externo-en-humanos?tca=YDZX1_CKfqGnGPf6Ei5zLrCkqjYXBx-PGm1YMJq0SLQ

Administración Nacional de Medicamentos. Alimentos y Tecnología Médica (ANMAT). Registro de repelentes de insectos inscriptos actualizado 07/24. Ministerio de Salud. Presidencia de la Nación. https://www.argentina.gob.ar/anmat/regulados/cosmeticos/listado-de-repelentes-de-insectos-inscriptos-uso-humano

Moore SJ, Debboun MA. In: Debboun M, Frances SP, Strickman D, editors. History of insect repellents. En Insect repellents: principles methods, and use. Florida: CRC; 2006. pp. 3–29.

Young G, Evans S. Safety and efficacy of deet and permethrin in the prevention of arthropod attack. Mil Med. 1998;163:324.

Article  PubMed  CAS  Google Scholar 

Antwi FB, Shama LM, Peterson RKD. Risk assessments for the insect repellents DEET and picaridin. Regul Toxicol Pharmacol. 2008;51(1):31–6. 10.1016/ j.yrtph.2008.03.002.

Article  PubMed  CAS  Google Scholar 

Osimitz TG, Murphy JV, Fell LA, Page B. Adverse events associated with the use of insect repellents containing N,N-diethyl-m-toluamide (DEET). Regul Toxicol Pharmacol. 2010;56(1):93–9. https://doi.org/10.1016/j.yrtph.2009.09.004.

Article  PubMed  CAS  Google Scholar 

Brown M, Hebert AA. Insect repellents: an overview. J Am Acad Dermatol. 1997;36:243–9.

Article  PubMed  CAS  Google Scholar 

Nentwig G. Use of repellents as prophylactic agents. Parasitol Res. 2003;1:S40–38.

Article  Google Scholar 

Ghali H, Albers SE. An updated review on the safety of N, N-diethyl‐meta‐toluamide insect repellent use in children and the efficacy of natural alternatives. Pediatr Dermatol. 2024;41(3):403–9.

Article  PubMed  Google Scholar 

World Health Organization (WHO). IR 3535 ethyl butylacetylaminoproprionate information: Interim specification. 2001 http://www.who.int/whopes/quality/en/Icaridin_spec_eval_Oct_2004. pdf).

World Health Organization (WHO). Specifications and evaluations for public health pesticides. Ethyl butylacetylaminopropionate - also known as IR3535® 3-(N-acetyl-N-butyl) aminopropionic acid ethyl ester. 2006.

Norris EJ, Coats JR. Current and future repellent technologies: the potential of spatial repellents and their place in mosquito-borne disease control. Int J Environ Res Public Health. 2017;14(2):124.

Article  PubMed  PubMed Central  Google Scholar 

Boeckh J, Breer H, Geier M, Hoever FP, Krüger BW, Nentwig G, Sass H. Acylate 1,3-aminopropanols as repellents against bloodsucking arthropods. Pestic Sci. 1996;48:359–73.

Article  CAS  Google Scholar 

Natarajan R, Basak SC, Balaban AT, Klun JA, Schmidt WF. Chirality index, molecular overlay, and biological activity of diastereoisomeric mosquito repellents. Pest Manag Sci. 2005;61:1193–201.

Article  PubMed  CAS  Google Scholar 

Basak SC, Natarajan R, Nowak W, Miszta P, Klun JA. Three-dimensional structure–activity relationships (3D-QSAR) for insect repellency of diastereoisomeric compounds: a hierarchical molecular overlay approach. SAR QSAR Environ Res. 2007;18:237–50.

Article  PubMed  CAS  Google Scholar 

Nguyen Q-BD, Vu M-AN, Hebert AA. Insect repellents: an updated review for the clinician. J Am Acad Dermatol. 2023;88(1):123–30. https://doi.org/10.1016/j.jaad.2018.10.053.

Article  PubMed  CAS  Google Scholar 

Centers for Disease Control and Prevention (CDC). Mosquitoes. Ticks & Other Arthropods CDC Yellow Book. 2024. https://wwwnc.cdc.gov/travel/yellowbook/2024/environmental-hazards-risks/mosquitoes-ticks-and-other-arthropods. Accessed Oct 2024.

Barasa SS, Ndiege IO, Lwande W, Hassanali A. Repellent activities of stereoisomers of p-menthane-3,8-diols against Anopheles gambiae (Diptera: Culicidae). J Med Entomol. 2002; 39:736–741. Akbar S. Handbook of 200 Medicinal Plants: A Comprehensive Review of their Traditional Medical Uses and Scientific Justifications. Springer; 2020.

Akbar S. Handbook of 200 medicinal plants: a comprehensive review of their traditional medical uses and scientific justifications. Springer; 2020.

Small E. Catnip—safer pesticide potential. Biodiversity. 2012;13(2): 118–126. doi:10.1080/14888386.2012.679879 EPA. Find the Repellent that is Right for You. US EPA. 2024 https://www.epa.gov/insect-repellents/find-repellent-right-you

EPA. Find the repellent that is right for you. US EPA. 2024. https://www.epa.gov/insect-repellents/find-repellent-right-you

Chauhan KR, Klun JA, Debboun M, Kramer M. Feeding deterrent effects of catnip oil components compared with two synthetic amides against Aedes aegypti. J Med Entomol. 2005;42(4):643–6. https://doi.org/10.1093/jmedent/42.4.643.

Article  PubMed  CAS  Google Scholar 

Songkro S, Hayook N, Jaisawang J, Maneenuan D, Chuchome T, Kaewnopparat N. Investigation of inclusion complexes of citronella oil, citronellal and citronellol with β-cyclodextrin for mosquito repellent. J Incl Phenom Macrocycl Chem. 2011;72(3–4):339–55. https://doi.org/10.1007/s10847-011-9985-7.

Article  CAS  Google Scholar 

Burfield T, Reekie S. Mosquitoes, malaria and essential oils. Int J Aromather. 2005;15(1):30–41.

Article  CAS  Google Scholar 

Yoon JK, Kim K-C, Cho Y, et al. Comparison of repellency effect of mosquito repellents for DEET, citronella, and fennel oil. J Parasitol Res. 2015;1–6. https://doi.org/10.1155/2015/361021.

Higuchi CT, Sales CC, Andréo-Filho N, et al. Development of a nanotechnology matrix-based citronella oil insect repellent to obtain a prolonged effect and evaluation of the safety and efficacy. Life. 2023;13(1):141. https://doi.org/10.3390/life13010141.

Article  PubMed