Abel, Sanchez‐Palencia Mercedes, Gomez‐Morales Jose Antonio, Gomez‐Capilla Vicente, Pedraza Laura, Boyero Rafael, Rosell Mª Esther, Fárez‐Vidal (2011) Gene expression profiling reveals novel biomarkers in nonsmall cell lung cancer. Int J Cancer Res 129(2):355–364. https://doi.org/10.1002/ijc.v129.210.1002/ijc.25704

Article  Google Scholar 

Ahmed IS, Rohe HJ, Twist KE, Mattingly MN, Craven RJ (2010) Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule. J Pharmacol Exp Ther 333(2):564–573

Article  CAS  PubMed  Google Scholar 

Bueno MLP, Saad STO, Roversi FM (2022) WNT5A in tumor development and progression: a comprehensive review. Biomed Pharmacother 155:113599

Article  CAS  PubMed  Google Scholar 

Cahill MA, Medlock AE (2017) Thoughts on interactions between PGRMC1 and diverse attested and potential hydrophobic ligands. J Steroid Biochem Mol Biol 171:11–33

Article  CAS  PubMed  Google Scholar 

Cahill MA, Neubauer H (2021) PGRMC proteins are coming of age: a special issue on the role of PGRMC1 and PGRMC2 in metabolism and cancer biology. Cancers 13(3):512

Article  PubMed  PubMed Central  Google Scholar 

Cahill MA, Jazayeri JA, Catalano SM, Toyokuni S, Kovacevic Z, Richardson DR (2016) The emerging role of progesterone receptor membrane component 1 (PGRMC1) in cancer biology. Biochim Biophys Acta BBA-Rev Cancer 2:339–349

Google Scholar 

Chandrashekar DS, Karthikeyan SK, Korla PK, Patel H, Shovon AR, Athar M, Netto GJ, Qin ZS, Kumar S, Manne U (2022) UALCAN: an update to the integrated cancer data analysis platform. Neoplasia 25:18–27

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen C, Zhang W (2019) Itraconazole alters the stem cell characteristics of A549 and NCI-H460 human lung cancer cells by suppressing Wnt signaling. Med Sci Monit Int Med J Exp Clin Res 25:9509

CAS  Google Scholar 

Feller D, Kun J, Ruzsics I, Rapp J, Sarosi V, Kvell K, Helyes Z, Pongracz JE (2018) Cigarette smoke-induced pulmonary inflammation becomes systemic by circulating extracellular vesicles containing Wnt5a and inflammatory cytokines. Front Immunol 9:1724

Article  PubMed  PubMed Central  Google Scholar 

Gan T, Chen W, Qin H, Huang S, Yang L, Fang Y, Pan L, Li Z, Chen G (2017) Clinical value and prospective pathway signaling of microrna-375 in lung adenocarcinoma: A study based on the cancer genome atlas (tcga), gene expression omnibus (geo) and bioinformatics analysis. Med Sci Monit Int Med J Exp Clin Res 23:2453

CAS  Google Scholar 

Gan H, Lin L, Hu N, Yang Y, Gao Y, Pei Y, Chen K, Sun B (2019) Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis. Thorac Cancer 10(4):744–750

Article  CAS  PubMed  PubMed Central  Google Scholar 

Garinet S, Wang P, Mansuet-Lupo A, Fournel L, Wislez M, Blons H (2022) Updated prognostic factors in localized NSCLC. Cancers 14(6):1400

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gor R, Sampath SS, Lazer LM, Ramalingam S (2021) RNA binding protein PUM1 promotes colon cancer cell proliferation and migration. Int J Biol Macromol 174:549–561

Article  CAS  PubMed  Google Scholar 

Gu B, Wang J, Song Y, Wang Q, Wu Q (2019) microRNA-383 regulates cell viability and apoptosis by mediating Wnt/β-catenin signaling pathway in non–small cell lung cancer. J Cell Biochem 120(5):7918–7926

Article  CAS  PubMed  Google Scholar 

Huang H, Chou H, Law C, Chang W, Wen T, Liao E, Lin M, Lin L, Wei Y, Tsai Y (2020) Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis. J Cell Mol Med 24(17):9737–9751

Article  CAS  PubMed  PubMed Central  Google Scholar 

Intlekofer KA, Clements K, Woods H, Adams H, Suvorov A, Petersen SL (2019) Progesterone receptor membrane component 1 inhibits tumor necrosis factor alpha induction of gene expression in neural cells. PLoS ONE 14(4):e0215389

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim JY, Kim SY, Choi HS, Kim MK, Lee HM, Jang Y-J, Ryu CJ (2018) Progesterone Receptor Membrane Component 1 suppresses the p53 and Wnt/β-catenin pathways to promote human pluripotent stem cell self-renewal. Sci Rep 8(1):1–16

Google Scholar 

Kim JY, Kim SY, Choi HS, An S, Ryu CJ (2019) Epitope mapping of anti-PGRMC1 antibodies reveals the non-conventional membrane topology of PGRMC1 on the cell surface. Sci Rep 9(1):1–9

Google Scholar 

Lazer LM, Sadhasivam B, Palaniyandi K, Muthuswamy T, Ramachandran I, Balakrishnan A, Pathak S, Narayan S, Ramalingam S (2018) Chitosan-based nano-formulation enhances the anticancer efficacy of hesperetin. Int J Biol Macromol 107:1988–1998

Article  Google Scholar 

Li H, Tong F, Meng R, Peng L, Wang J, Zhang R, Dong X (2021) E2F1-mediated repression of WNT5A expression promotes brain metastasis dependent on the ERK1/2 pathway in EGFR-mutant non-small cell lung cancer. Cell Mol Life Sci 78(6):2877–2891

Article  CAS  PubMed  Google Scholar 

Lin Y, Higashisaka K, Shintani T, Maki A, Hanamuro S, Haga Y, Maeda S, Tsujino H, Nagano K, Fujio Y (2020) Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells. Sci Rep 10(1):1–10

Google Scholar 

Luan Y, Tang N, Yang J, Liu S, Cheng C, Wang Y, Chen C, Guo Y, Wang H, Zhao W (2022) Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells. Nucleic Acids Res. https://doi.org/10.1093/nar/gkac053

Article  PubMed  PubMed Central  Google Scholar 

McGuire MR, Espenshade PJ (2022) PGRMC1: an enigmatic heme-binding protein. Pharmacol Ther 241:108326

Article  PubMed  PubMed Central  Google Scholar 

Melosky B, Kambartel K, Haentschel M, Bennetts M, Nickens DJ, Brinkmann J, Kayser A, Moran M, Cappuzzo F (2022) Worldwide prevalence of epidermal growth factor receptor mutations in non-small cell lung cancer: a meta-analysis. Mol Diagn Ther 26(1):7–18

Article  CAS  PubMed  Google Scholar 

Pedroza DA, Subramani R, Tiula K, Do A, Rashiraj N, Galvez A, Chatterjee A, Bencomo A, Rivera S, Lakshmanaswamy R (2021) Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation. Lab Invest 101(6):733–744

Article  CAS  PubMed  Google Scholar 

Piel RB III, Shiferaw MT, Vashisht AA, Marcero JR, Praissman JL, Phillips JD, Wohlschlegel JA, Medlock AE (2016) A novel role for progesterone receptor membrane component 1 (PGRMC1): a partner and regulator of ferrochelatase. Biochemistry 55(37):5204–5217

Article  CAS  PubMed  Google Scholar 

Pru JK (2022) Pleiotropic Actions of PGRMC Proteins in Cancer. Endocrinology 163(7):bqac078

Article  PubMed  PubMed Central  Google Scholar 

Rapp J, Jaromi L, Kvell K, Miskei G, Pongracz JE (2017) WNT signaling–lung cancer is no exception. Respir Res 18(1):1–16

Article  Google Scholar 

Ruan X, Mueck AO (2022) Clinical importance of PGRMC1 in hormone responsive breast cancer. Breast Care 18(3):172–178. https://doi.org/10.1159/000527969

Article  PubMed  PubMed Central  Google Scholar 

Ryu CS, Klein K, Zanger UM (2017) Membrane associated progesterone receptors: promiscuous proteins with pleiotropic functions–focus on interactions with cytochromes P450. Front Pharmacol 8:159

Article  PubMed  PubMed Central  Google Scholar 

Solairaja S, Ramalingam S, Dunna NR, Venkatabalasubramanian S (2022) Progesterone receptor membrane component 1 and its accomplice: emerging therapeutic targets in lung cancer. Endocr Metab Immune Disord-Drug Targets Former Curr Drug Targets-Immune Endocr Metab Disord 22(6):601–611

Article  CAS  Google Scholar 

Tang Z, Li C, Kang B, Gao G, Li C, Zhang Z (2017) Gepia: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res 45:W98–W102

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tenjin Y, Kudoh S, Kubota S, Yamada T, Matsuo A, Sato Y, Ichimura T, Kohrogi H, Sashida G, Sakagami T (2019) Ascl1-induced Wnt11 regulates neuroendocrine differentiation, cell proliferation, and E-cadherin expression in small-cell lung cancer and Wnt11 regulates small-cell lung cancer biology. Lab Invest 99(11):1622–1635