Monteiro CA, Cannon G, Moubarac JC, Levy RB, Louzada MLC, Jaime PC. The UN decade of nutrition, the NOVA food classification and the trouble with ultra-processing. Public Health Nutr. 2018;21:5–17. https://doi.org/10.1017/S1368980017000234.

Article  PubMed  Google Scholar 

Jones JM. Food processing: criteria for dietary guidance and public health? Proc Nutr Soc. 2019;78:4–18. https://doi.org/10.1017/S0029665118002513.

Article  PubMed  Google Scholar 

Gibney MJ, Forde CG, Mullally D, Gibney ER. Ultra-processed foods in human health: a critical appraisal. Am J Clin Nutr. 2017;106:717–24. https://doi.org/10.3945/ajcn.117.160440.

Article  CAS  PubMed  Google Scholar 

Bradbury KE, Mackay S. Ultra-processed foods linked to higher mortality. BMJ. 2024;385:q793 https://doi.org/10.1136/bmj.q793.

Article  PubMed  Google Scholar 

Vitale M, Costabile G, Testa R, D’Abbronzo G, Nettore IC, Macchia PE, et al. Ultra-processed foods and human health: a systematic review and meta-analysis of prospective cohort studies. Adv Nutr. 2024;15:100121 https://doi.org/10.1016/j.advnut.2023.09.009.

Article  PubMed  Google Scholar 

Cordova R, Viallon V, Fontvieille E, Peruchet-Noray L, Jansana A, Wagner KH, et al. Consumption of ultra-processed foods and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study. Lancet Reg Health Eur. 2023;35:100771 https://doi.org/10.1016/j.lanepe.2023.100771.

Article  PubMed  PubMed Central  Google Scholar 

Vellinga RE, van den Boomgaard I, M A Boer J, van der Schouw YT, Harbers MC, Verschuren WMM, et al. Different levels of ultraprocessed food and beverage consumption and associations with environmental sustainability and all-cause mortality in EPIC-NL. Am J Clin Nutr. 2023;118:103–13. https://doi.org/10.1016/j.ajcnut.2023.05.021.

Article  CAS  PubMed  Google Scholar 

Chen Z, Khandpur N, Desjardins C, Wang L, Monteiro CA, Rossato SL, et al. Ultra-processed food consumption and risk of type 2 diabetes: three large prospective U.S. cohort studies. Diabetes Care. 2023;46:1335–44. https://doi.org/10.2337/dc22-1993.

Article  PubMed  PubMed Central  Google Scholar 

Beslay M, Srour B, Mejean C, Alles B, Fiolet T, Debras C, et al. Ultra-processed food intake in association with BMI change and risk of overweight and obesity: a prospective analysis of the French NutriNet-Sante cohort. PLoS Med. 2020;17:e1003256. https://doi.org/10.1371/journal.pmed.1003256.

Article  PubMed  PubMed Central  Google Scholar 

Fiolet T, Srour B, Sellem L, Kesse-Guyot E, Alles B, Mejean C, et al. Consumption of ultra-processed foods and cancer risk: results from NutriNet-Sante prospective cohort. BMJ. 2018;360:k322. https://doi.org/10.1136/bmj.k322.

Article  PubMed  PubMed Central  Google Scholar 

Srour B, Fezeu LK, Kesse-Guyot E, Alles B, Mejean C, Andrianasolo RM, et al. Ultra-processed food intake and risk of cardiovascular disease: prospective cohort study (NutriNet-Sante). BMJ. 2019;365:l1451. https://doi.org/10.1136/bmj.l1451.

Article  PubMed  PubMed Central  Google Scholar 

Srour B, Fezeu LK, Kesse-Guyot E, Alles B, Debras C, Druesne-Pecollo N, et al. Ultraprocessed food consumption and risk of type 2 diabetes among participants of the NutriNet-Sante prospective cohort. JAMA Intern Med. 2020;180:283–91. https://doi.org/10.1001/jamainternmed.2019.5942.

Article  PubMed  Google Scholar 

Sellem L, Srour B, Javaux G, Chazelas E, Chassaing B, Viennois E, et al. Food additive emulsifiers and cancer risk: results from the French prospective NutriNet-Sante cohort. PLoS Med. 2024;21:e1004338. https://doi.org/10.1371/journal.pmed.1004338.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hang D, Du M, Wang L, Wang K, Fang Z, Khandpur N, et al. Ultra-processed food consumption and mortality among patients with stages I-III colorectal cancer: a prospective cohort study. EClinicalMedicine. 2024;71:102572. https://doi.org/10.1016/j.eclinm.2024.102572.

Article  PubMed  PubMed Central  Google Scholar 

Visioli F, Marangoni F, Fogliano V, Del Rio D, Martinez JA, Kuhnle G, et al. The ultra-processed foods hypothesis: a product processed well beyond the basic ingredients in the package. Nutr Res Rev. 2023;36:340–50. https://doi.org/10.1017/S0954422422000117.

Article  CAS  PubMed  Google Scholar 

Bonaccio M, Di Castelnuovo A, Costanzo S, De Curtis A, Persichillo M, Sofi F, et al. Ultra-processed food consumption is associated with increased risk of all-cause and cardiovascular mortality in the Moli-sani Study. Am J Clin Nutr. 2021;113:446–55. https://doi.org/10.1093/ajcn/nqaa299.

Article  CAS  PubMed  Google Scholar 

Chen X, Chu J, Hu W, Sun N, He Q, Liu S, et al. Associations of ultra-processed food consumption with cardiovascular disease and all-cause mortality: UK Biobank. Eur J Public Health. 2022;32:779–85. https://doi.org/10.1093/eurpub/ckac104.

Article  PubMed  PubMed Central  Google Scholar 

Wang L, Pan XF, Munro HM, Shrubsole MJ, Yu D. Consumption of ultra-processed foods and all-cause and cause-specific mortality in the Southern Community Cohort Study. Clin Nutr. 2023;42:1866–74. https://doi.org/10.1016/j.clnu.2023.08.012.

Article  CAS  PubMed  Google Scholar 

Lane MM, Gamage E, Du S, Ashtree DN, McGuinness AJ, Gauci S, et al. Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses. BMJ. 2024;384:e077310. https://doi.org/10.1136/bmj-2023-077310.

Article  PubMed  PubMed Central  Google Scholar 

Rico-Campa A, Martinez-Gonzalez MA, Alvarez-Alvarez I, Mendonca RD, de la Fuente-Arrillaga C, Gomez-Donoso C, et al. Association between consumption of ultra-processed foods and all cause mortality: SUN prospective cohort study. BMJ. 2019;365:l1949. https://doi.org/10.1136/bmj.l1949.

Article  PubMed  PubMed Central  Google Scholar 

Valicente VM, Peng CH, Pacheco KN, Lin L, Kielb EI, Dawoodani E, et al. Ultraprocessed foods and obesity risk: a critical review of reported mechanisms. Adv Nutr. 2023;14:718–38. https://doi.org/10.1016/j.advnut.2023.04.006.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Monteiro CA, Martinez-Steele E, Cannon G. Reasons to avoid ultra-processed foods. BMJ. 2024;384:q439. https://doi.org/10.1136/bmj.q439.

Article  PubMed  Google Scholar 

Schnabel L, Kesse-Guyot E, Alles B, Touvier M, Srour B, Hercberg S, et al. Association between ultraprocessed food consumption and risk of mortality among middle-aged adults in France. JAMA Intern Med. 2019;179:490–8. https://doi.org/10.1001/jamainternmed.2018.7289.

Article  PubMed  PubMed Central  Google Scholar 

Greenland S, Longnecker MP. Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. Am J Epidemiol. 1992;135:1301–9. https://doi.org/10.1093/oxfordjournals.aje.a116237.

Article  CAS  PubMed  Google Scholar