Unudurthi SD, Nassal DM, Patel NJ, Thomas E, Yu J, Pierson CG, Bansal SS, Mohler PJ, Hund TJ. Fibroblast growth factor-inducible 14 mediates macrophage infiltration in heart to promote pressure overload-induced cardiac dysfunction. Life Sci. 2020;247:117440.
Article CAS PubMed PubMed Central Google Scholar
Roger VL, Heart Failure. In International Encyclopedia of Public Health, 2017; pp 520–526. https://doi.org/10.1016/B978-0-12-803678-5.00199-5
Mamas MA, Sperrin M, Watson MC, Coutts A, Wilde K, Burton C, Kadam UT, Kwok CS, Clark AB, Murchie P, Buchan I, Hannaford PC, Myint PK. Do patients have worse outcomes in heart failure than in cancer? A primary care-based cohort study with 10-year follow-up in Scotland. Eur J Heart Fail. 2017;19(9):1095–104.
Nicin L, Wagner JUG, Luxan G, Dimmeler S. Fibroblast-mediated intercellular crosstalk in the healthy and diseased heart. FEBS Lett. 2022;596(5):638–54.
Article CAS PubMed Google Scholar
Travers JG, Kamal FA, Robbins J, Yutzey KE, Blaxall BC. Cardiac Fibrosis: The Fibroblast Awakens. Circ Res. 2016;118(6):1021–40.
Article CAS PubMed PubMed Central Google Scholar
Fan D, Takawale A, Lee J, Kassiri Z. Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease. Fibrogenesis Tissue Repair. 2012;5(1):15.
Article CAS PubMed PubMed Central Google Scholar
Dick SA, Epelman S. Chronic Heart Failure and Inflammation: What Do We Really Know? Circ Res. 2016;119(1):159–76.
Article CAS PubMed Google Scholar
Reina-Couto M, Pereira-Terra P, Quelhas-Santos J, Silva-Pereira C, Albino-Teixeira A, Sousa T. Inflammation in Human Heart Failure: Major Mediators and Therapeutic Targets. Front Physiol. 2021;12:746494.
Article PubMed PubMed Central Google Scholar
Van Linthout S, Tschope C. Inflammation - Cause or Consequence of Heart Failure or Both? Curr Heart Fail Rep. 2017;14(4):251–65.
Article PubMed PubMed Central Google Scholar
Dutka M, Bobinski R, Ulman-Wlodarz I, Hajduga M, Bujok J, Pajak C, Cwiertnia M. Various aspects of inflammation in heart failure. Heart Fail Rev. 2020;25(3):537–48.
Samanta S, Rajasingh S, Drosos N, Zhou Z, Dawn B, Rajasingh J. Exosomes: new molecular targets of diseases. Acta Pharmacol Sin. 2018;39(4):501–13.
Article CAS PubMed Google Scholar
Wu X, Iroegbu CD, Peng J, Guo J, Yang J, Fan C. Cell Death and Exosomes Regulation After Myocardial Infarction and Ischemia-Reperfusion. Front Cell Dev Biol. 2021;9:673677.
Article PubMed PubMed Central Google Scholar
Kalluri R, LeBleu VS, The biology, function, and biomedical applications of exosomes. Science 2020, 367 (6478). https://doi.org/10.1126/science.aau6977
Wang L, Zhang J. Exosomal lncRNA AK139128 Derived from Hypoxic Cardiomyocytes Promotes Apoptosis and Inhibits Cell Proliferation in Cardiac Fibroblasts. Int J Nanomedicine. 2020;15:3363–76.
Article CAS PubMed PubMed Central Google Scholar
Berumen Sanchez G, Bunn KE, Pua HH, Rafat M. Extracellular vesicles: mediators of intercellular communication in tissue injury and disease. Cell Commun Signal. 2021;19(1):104.
Article CAS PubMed PubMed Central Google Scholar
Devhare PB, Ray RB. Extracellular vesicles: Novel mediator for cell to cell communications in liver pathogenesis. Mol Aspects Med. 2018;60:115–22.
Article CAS PubMed Google Scholar
Khan M, Nickoloff E, Abramova T, Johnson J, Verma SK, Krishnamurthy P, Mackie AR, Vaughan E, Garikipati VN, Benedict C, Ramirez V, Lambers E, Ito A, Gao E, Misener S, Luongo T, Elrod J, Qin G, Houser SR, Koch WJ, Kishore R. Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction. Circ Res. 2015;117(1):52–64.
Article CAS PubMed PubMed Central Google Scholar
Agarwal U, George A, Bhutani S, Ghosh-Choudhary S, Maxwell JT, Brown ME, Mehta Y, Platt MO, Liang Y, Sahoo S, Davis ME. Experimental, Systems, and Computational Approaches to Understanding the MicroRNA-Mediated Reparative Potential of Cardiac Progenitor Cell-Derived Exosomes From Pediatric Patients. Circ Res. 2017;120(4):701–12.
Article CAS PubMed Google Scholar
Fu S, Zhang Y, Li Y, Luo L, Zhao Y, Yao Y. Extracellular vesicles in cardiovascular diseases. Cell Death Discov. 2020;6:68.
Article CAS PubMed PubMed Central Google Scholar
Akhmerov A, Parimon T. Extracellular Vesicles, Inflammation, and Cardiovascular Disease. Cells. 2022;11(14):2229.
Article CAS PubMed PubMed Central Google Scholar
Khandagale A, Lindahl B, Lind SB, Shevchenko G, Siegbahn A, Christersson C. Plasma-derived extracellular vesicles from myocardial infarction patients inhibits tumor necrosis factor-alpha induced cardiac cell death. Curr Res Transl Med. 2022;70(2):103323.
Chong SY, Lee CK, Huang C, Ou YH, Charles CJ, Richards AM, Neupane YR, Pavon MV, Zharkova O, Pastorin G, Wang, JW, Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers. Int J Mol Sci 2019 20 (13). https://doi.org/10.3390/ijms20133272
Simeone P Bologna G, Lanuti P, Pierdomenico L, Guagnano MT, Pieragostino D, Del Boccio P, Vergara D, Marchisio M, Miscia S, Mariani-Costantini, R (2020) Extracellular Vesicles as Signaling Mediators and Disease Biomarkers across Biological Barriers. Int J Mol Sci 21 (7). https://doi.org/10.3390/ijms21072514
Ramirez SH, Andrews AM, Paul D, Pachter JS. Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers. Fluids Barriers CNS. 2018;15(1):19.
Article PubMed PubMed Central Google Scholar
Xu Y, Wu A, Chen J, Song X, Chen M, Liu Q. Limb-Bud and Heart (LBH) Upregulation in Cardiomyocytes under Hypoxia Promotes the Activation of Cardiac Fibroblasts via Exosome Secretion. Mediators Inflamm. 2022;2022:8939449.
Article PubMed PubMed Central Google Scholar
Sahoo S, Adamiak M, Mathiyalagan P, Kenneweg F, Kafert-Kasting S, Thum T. Therapeutic and Diagnostic Translation of Extracellular Vesicles in Cardiovascular Diseases: Roadmap to the Clinic. Circulation. 2021;143(14):1426–49.
Article CAS PubMed PubMed Central Google Scholar
Verbree-Willemsen L, Zhang YN, Ibrahim I, Ooi SBS, Wang JW, Mazlan MI, Kuan WS, Chan SP, Peelen LM, Grobbee DE, Richards AM, Lam CSP, de Kleijn DPV. Extracellular vesicle Cystatin C and CD14 are associated with both renal dysfunction and heart failure. ESC Heart Fail. 2020;7(5):2240–9.
Article PubMed PubMed Central Google Scholar
Alghamdi M, Alamry SA, Bahlas SM, Uversky VN, Redwan EM. Circulating extracellular vesicles and rheumatoid arthritis: a proteomic analysis. Cell Mol Life Sci. 2021;79(1):25.
Article PubMed PubMed Central Google Scholar
Viola M, de Jager SCA, Sluijter JPG, Targeting Inflammation after Myocardial Infarction: A Therapeutic Opportunity for Extracellular Vesicles? Int J Mol Sci 2021, 22 (15)
Vedin O, Lam CSP, Koh AS, Benson L, Teng THK, Tay WT, Braun OO, Savarese G, Dahlstrom U, Lund LH, Significance of Ischemic Heart Disease in Patients With Heart Failure and Preserved, Midrange, and Reduced Ejection Fraction: A Nationwide Cohort Study. Circ Heart Fail 2017, 10 (6). https://doi.org/10.1161/CIRCHEARTFAILURE.117.003875
Fang J, Zhang Y, Chen D, Zheng Y, Jiang J. Exosomes and Exosomal Cargos: A Promising World for Ventricular Remodeling Following Myocardial Infarction. Int J Nanomedicine. 2022;17:4699–719.
Article CAS PubMed PubMed Central Google Scholar
Zhen K, Wei X, Zhi Z, Zhang S, Cui L, Li Y, Chen X, Yao J, Zhang H, Comparison of Different Isolation Methods for Plasma-Derived Extracellular Vesicles in Patients with Hyperlipidemia. Life (Basel) 2022, 12 (11). https://doi.org/10.3390/life12111942
Schulze PC. Myocardial lipid accumulation and lipotoxicity in heart failure. J Lipid Res. 2009;50(11):2137–8.
Article CAS PubMed PubMed Central Google Scholar
Sletten AC, Peterson LR, Schaffer JE. Manifestations and mechanisms of myocardial lipotoxicity in obesity. J Intern Med. 2018;284(5):478–91.
Comments (0)