Abedi M, Hajinejad M, Atabi F, Sahab-Negah S (2022) Exosome derived from human neural stem cells improves motor activity and neurogenesis in a traumatic brain injury model. BioMed Res Int 2022:6409346

Article  PubMed  PubMed Central  Google Scholar 

Acar H, Srivastava S, Chung EJ, Schnorenberg MR, Barrett JC, LaBelle JL, Tirrell M (2017) Self-assembling peptide-based building blocks in medical applications. Adv Drug Deliv Rev 110:65–79

Article  PubMed  Google Scholar 

Alhadidi QM, Bahader GA, Arvola O, Kitchen P, Shah ZA, Salman MM (2023) Astrocytes in functional recovery following central nervous system injuries. J Physiol 602(13):3069–3096

Article  PubMed  Google Scholar 

Ando K, Imagama S, Ito Z, Kobayashi K, Hida T, Nakashima H, Ito K, Tsushima M, Ishikawa Y, Matsumoto A, Nishida K, Nishida Y, Ishiguro N (2016) Self-assembling peptide reduces glial scarring attenuates posttraumatic inflammation and promotes neurite outgrowth of spinal motor neurons. Spine 41(20):E1201–E1207. https://doi.org/10.1097/BRS.0000000000001611

Article  PubMed  Google Scholar 

Ashammakhi N, Ahadian S, Darabi MA, El Tahchi M, Lee J, Suthiwanich K, ... Khademhosseini A (2019) Minimally invasive and regenerative therapeutics. Adv Mater 31(1):1804041

Balestri W, Sharma R, da Silva VA, Bobotis BC, Curle AJ, Kothakota V, ... Jones JL (2024) Modeling the neuroimmune system in Alzheimer’s and Parkinson’s diseases. J Neuroinflammation 21(1):32

Bolan F, Dickie BR, Cook JR, Thomas JM, Pinteaux E, Allan SM et al (2023) Intracerebral administration of a novel self-assembling peptide hydrogel is safe and supports cell proliferation in experimental intracerebral haemorrhage. Transl Stroke Res 15(5):986–1004

Article  PubMed  PubMed Central  Google Scholar 

Castillo-Díaz LA, Ruiz-Pacheco JA, Elsawy MA, Reyes-Martínez JE, Enríquez-Rodríguez AI (2020) Self-assembling peptides as an emerging platform for the treatment of metabolic syndrome. Int J Nanomed 2020:10349–10370

Article  Google Scholar 

Cheng T-Y, Chen M-H, Chang W-H, Huang M-Y, Wang T-W (2013) Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering. Biomaterials 34(8):2005–2016

Article  CAS  PubMed  Google Scholar 

Cheng X, Wang J, Sun X, Shao L, Guo Z, Li Y (2019) Morphological and functional alterations of astrocytes responding to traumatic brain injury. J Integr Neurosci 18(2):203–215

Article  PubMed  Google Scholar 

Chronopoulou L, Togna AR, Guarguaglini G, Masci G, Giammaruco F, Togna GI, Palocci C (2012) Self-assembling peptide hydrogels promote microglial cells proliferation and NGF production. Soft Matter 8(21):5784–5790

Article  CAS  Google Scholar 

Chu F, Shi M, Zheng C, Shen D, Zhu J, Zheng X, Cui L (2018) The roles of macrophages and microglia in multiple sclerosis and experimental autoimmune encephalomyelitis. J Neuroimmunol 318:1–7

Article  CAS  PubMed  Google Scholar 

Cui G-H, Shao S-J, Yang J-J, Liu J-R, Guo H-D (2016) Designer self-assemble peptides maximize the therapeutic benefits of neural stem cell transplantation for Alzheimer’s disease via enhancing neuron differentiation and paracrine action. Mol Neurobiol 53:1108–1123

Article  CAS  PubMed  Google Scholar 

Delfi M, Sartorius R, Ashrafizadeh M, Sharifi E, Zhang Y, De Berardinis P, ... Smith BR (2021) Self-assembled peptide and protein nanostructures for anti-cancer therapy: targeted delivery, stimuli-responsive devices and immunotherapy. Nano Today 38:101119

Donat CK, Scott G, Gentleman SM, Sastre M (2017) Microglial activation in traumatic brain injury. Front Aging Neurosci 9:208

Article  PubMed  PubMed Central  Google Scholar 

Dong R, Huang R, Wang J, Liu H, Xu Z (2021) Effects of microglial activation and polarization on brain injury after stroke. Front Neurol 12:620948

Article  PubMed  PubMed Central  Google Scholar 

Donnelly CR, Andriessen AS, Chen G, Wang K, Jiang C, Maixner W, Ji R-R (2020) Central nervous system targets: glial cell mechanisms in chronic pain. Neurotherapeutics 17:846–860

Article  PubMed  PubMed Central  Google Scholar 

Dordoe C, Huang W, Bwalya C, Wang X, Shen B, Wang H et al (2023) The role of microglial activation on ischemic stroke: modulation by fibroblast growth factors. Cytokine Growth Factor Rev 2023

Escartin C, Galea E, Lakatos A, O’Callaghan JP, Petzold GC, Serrano-Pozo A, ... Agarwal A (2021) Reactive astrocyte nomenclature, definitions, and future directions. Nat Neurosci 24(3):312–325

Eskandari S, Guerin T, Toth I, Stephenson RJ (2017) Recent advances in self-assembled peptides: implications for targeted drug delivery and vaccine engineering. Adv Drug Deliv Rev 110:169–187

Article  PubMed  Google Scholar 

Fan T, Yu X, Shen B, Sun L (2017) Peptide self-assembled nanostructures for drug delivery applications. J Nanomater 1:4562474

Google Scholar 

Fitch MT, Silver J (2008) CNS injury glial scars and inflammation: Inhibitory extracellular matrices and regeneration failure. Experimental Neurology 209(2):294–301. https://doi.org/10.1016/j.expneurol.2007.05.014

Article  CAS  PubMed  Google Scholar 

Gao C, Jiang J, Tan Y, Chen S (2023a) Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets. Signal Transduct Target Ther 8(1):359

Article  PubMed  PubMed Central  Google Scholar 

Gao L, Pan X, Zhang JH, Xia Y (2023b) Glial cells: an important switch for the vascular function of the central nervous system. Front Cell Neurosci 17:1166770

Article  CAS  PubMed  Google Scholar 

Gelain F, Bottai D, Vescovi A, Zhang S (2006) Designer self-assembling peptide nanofiber scaffolds for adult mouse neural stem cell 3-dimensional cultures. PLoS ONE 1(1):e119

Article  PubMed  PubMed Central  Google Scholar 

Ghandy N, Ebrahimzadeh-Bideskan A, Gorji A, Negah SS (2023) Co-transplantation of novel Nano-SDF scaffold with human neural stem cells attenuates inflammatory responses and apoptosis in traumatic brain injury. Int Immunopharmacol 115:109709

Article  CAS  PubMed  Google Scholar 

Giovannoni F, Quintana FJ (2020) The role of astrocytes in CNS inflammation. Trends Immunol 41(9):805–819

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gongora-Benitez M, Tulla-Puche J, Albericio F (2014) Multifaceted roles of disulfide bonds. Peptides as therapeutics. Chem Rev 114(2):901-926

Guo S, Wang H, Yin Y (2022a) Microglia polarization from M1 to M2 in neurodegenerative diseases. Front Aging Neurosci 14:815347

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guo W, Ma Y, Hu L, Feng Y, Liu Y, Yi X, ... Tang F (2022b) Modification strategies for ionic complementary self-assembling peptides: taking RADA16-I as an example. Polymers 14(23):5221

Hajinejad M, Ebrahimzadeh MH, Ebrahimzadeh-bideskan A, Rajabian A, Gorji A, Sahab Negah S (2023) Exosomes and nano-SDF scaffold as a cell-free-based treatment strategy improve traumatic brain injury mechanisms by decreasing oxidative stress, neuroinflammation, and increasing neurogenesis. Stem Cell Rev Rep 19(4):1001–1018

Article  CAS  PubMed  Google Scholar 

Hajinejad M, Sahab-Negah S (2021) Neuroinflammation: the next target of exosomal microRNAs derived from mesenchymal stem cells in the context of neurological disorders. J Cell Physiol 236(12):8070–8081

Article  CAS  PubMed  Google Scholar 

Hassannejad Z, Zadegan SA, Vaccaro AR, Rahimi-Movaghar V, Sabzevari O (2019) Biofunctionalized peptide-based hydrogel as an injectable scaffold for BDNF delivery can improve regeneration after spinal cord injury. Injury 50(2):278–285

Article  PubMed  Google Scholar 

Hellal F, Hurtado A, Ruschel J, Flynn KC, Laskowski CJ, Umlauf M, ... Bixby J (2011) Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury. Science 331(6019):928–931

Hernández IH, Villa-González M, Martín G, Soto M, Pérez-Álvarez MJ (2021) Glial cells as therapeutic approaches in brain ischemia-reperfusion injury. Cells 10(7):1639

Article  PubMed  PubMed Central  Google Scholar 

Hong JY, Kim SH, Seo Y, Jeon J, Davaa G, Kim SH, Hyun JK (2022) Self-assembling peptide gels promote angiogenesis and functional recovery after spinal cord injury in rats. J Tissue Eng 13:20417314221086492

Article  PubMed  PubMed Central  Google Scholar 

Isik S, YemanKiyak B, Akbayir R, Seyhali R, Arpaci T (2023) Microglia mediated neuroinflammation in Parkinson’s disease. Cells 12(7):1012

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jahanbazi Jahan-Abad A, Sahab Negah S, Hosseini Ravandi H, Ghasemi S, Borhani-Haghighi M, Stummer W, ... Khaleghi Ghadiri M (2018) Human neural stem/progenitor cells derived from epileptic human brain in a self-assembling peptide nanoscaffold improve traumatic brain injury in rats. Mol Neurobiol 55:9122–9138

Jiang CT, Wu WF, Deng YH, Ge JW (2020) Modulators of microglia activation and polarization in ischemic stroke. Mol Med Rep 21(5):2006–2018

CAS  PubMed