aDepartment of Medicine, Division of Nephrology

bDepartment of Medicine, Division of Endocrinology

cDepartment of Cellular and Molecular Pharmacology, University of California at San Francisco, San Francisco, California, USA

Correspondence to David Pearce, MD, Genentech Hall, Rm N272C, University of California, San Francisco, 600 16th St., San Francisco, CA 94158, USA. Tel: +1 628 206 8843; fax: +1 415 502 8644; e-mail: [email protected]