Particulate matter-induced gene expression patterns in human-derived cells based on 11 public gene expression datasets

Abbas I et al (2019) In vitro evaluation of organic extractable matter from ambient PM2.5 using human bronchial epithelial BEAS-2B cells: cytotoxicity, oxidative stress, pro-inflammatory response, genotoxicity, and cell cycle deregulation. Environ Res 171:510–522. https://doi.org/10.1016/j.envres.2019.01.052

Article  CAS  PubMed  Google Scholar 

Barrett T et al (2012) NCBI GEO: archive for functional genomics data sets—update. Nucleic Acids Res 41:D991–D995

Article  PubMed  PubMed Central  Google Scholar 

Chu J-H, Hart JE, Chhabra D, Garshick E, Raby BA, Laden F (2016) Gene expression network analyses in response to air pollution exposures in the trucking industry. Environ Health 15:101. https://doi.org/10.1186/s12940-016-0187-z

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guo C, Lv S, Liu Y, Li Y (2022) Biomarkers for the adverse effects on respiratory system health associated with atmospheric particulate matter exposure. J Hazard Mater 421:126760. https://doi.org/10.1016/j.jhazmat.2021.126760

Article  CAS  PubMed  Google Scholar 

Huang SK et al (2021) Effect of concentration and duration of particulate matter exposure on the transcriptome and DNA methylome of bronchial epithelial cells. Environ Epigenetics 7:dvaa022. https://doi.org/10.1093/eep/dvaa022

Article  CAS  Google Scholar 

Kim DI, Song M-K, Kim H-I, Han KM, Lee K (2020) Diesel Exhaust particulates Induce Neutrophilic Lung inflammation by modulating endoplasmic reticulum stress-mediated CXCL1/KC expression in alveolar macrophages. Molecules 25. https://doi.org/10.3390/molecules25246046

Lee Y-G, Lee P-H, Choi S-M, An M-H, Jang A-S (2021) Effects of Air pollutants on Airway diseases. Int J Environ Res Public Health 18. https://doi.org/10.3390/ijerph18189905

Liu W-C, Chiu H-W, Chou C-L, Chiu Y-J, Lee Y-H (2023) Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis. Environ Pollut 318:120871. https://doi.org/10.1016/j.envpol.2022.120871

Article  CAS  PubMed  Google Scholar 

Mazzoli-Rocha F, Fernandes S, Einicker-Lamas M, Zin WA (2010) Roles of oxidative stress in signaling and inflammation induced by particulate matter. Cell Biol Toxicol 26:481–498

Article  CAS  PubMed  Google Scholar 

Misiukiewicz-Stępien P et al (2022) RNA-Seq analysis of UPM-Exposed epithelium co-cultivated with macrophages and dendritic cells in Obstructive Lung diseases. Int J Mol Sci 23. https://doi.org/10.3390/ijms23169125

Montgomery MT et al (2020) Genome-wide analysis reveals Mucociliary Remodeling of the nasal Airway Epithelium Induced by Urban PM(2.5). Am J Respiratory Cell Mol Biology 63:172–184. https://doi.org/10.1165/rcmb.2019-0454OC

Article  CAS  Google Scholar 

Park E-J et al (2017) Ambient fine particulate matters induce cell death and inflammatory response by influencing mitochondria function in human corneal epithelial cells. Environ Res 159:595–605

Article  CAS  PubMed  Google Scholar 

Peretz A et al (2007) Diesel Exhaust Inhalation and Assessment of Peripheral Blood mononuclear cell gene transcription effects: an exploratory study of healthy human volunteers. Inhalation Toxicol 19:1107–1119. https://doi.org/10.1080/08958370701665384

Article  CAS  Google Scholar 

Rao X, Zhong J, Brook RD, Rajagopalan S (2018) Effect of particulate matter air pollution on cardiovascular oxidative stress pathways. Antioxid Redox Signal 28:797–818

Article  CAS  PubMed  PubMed Central  Google Scholar 

Risom L, Møller P, Loft S (2005) Oxidative stress-induced DNA damage by particulate air pollution. Mutat Research/Fundamental Mol Mech Mutagen 592:119–137

Article  CAS  Google Scholar 

Romani A et al (2018) Keratinocytes oxidative damage mechanisms related to airborne particle matter exposure. Mech Ageing Dev 172:86–95

Article  CAS  PubMed  Google Scholar 

Ru Q et al (2017) Lipopolysaccharide accelerates fine particulate matter-induced cell apoptosis in human lung bronchial epithelial cells. Int J Occup Med Environ Health 31:173–183

PubMed  Google Scholar 

Sukuman T, Ueda K, Sujaritpong S, Praekunatham H, Punnasiri K, Wimuktayon T, Prapaspongsa T (2023) Health impacts from PM2. 5 Exposure Using Environmental Epidemiology and Health Risk Assessment: a review. Appl Environ Res 45

Sung Y-Y et al (2023) Siraitia Grosvenorii Extract attenuates airway inflammation in a mouse model of respiratory Disease Induced by Particulate Matter 10 plus Diesel Exhaust particles. Nutrients 15. https://doi.org/10.3390/nu15194140

Troy NM, Hollams EM, Holt PG, Bosco A (2016) Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses. BMC Med Genom 9:9. https://doi.org/10.1186/s12920-016-0171-z

Article  CAS  Google Scholar 

van Eeden SF et al (2001) Cytokines involved in the systemic inflammatory response induced by exposure to particulate matter air pollutants (PM10). Am J Respir Crit Care Med 164:826–830

Article  PubMed  Google Scholar 

Wu J et al (2017) Fine particle matters induce DNA damage and G2/M cell cycle arrest in human bronchial epithelial BEAS-2B cells. Environ Sci Pollut Res 24:25071–25081

Article  CAS  Google Scholar 

Xu F et al (2020) Investigation of the chemical components of ambient fine particulate matter (PM2. 5) associated with in vitro cellular responses to oxidative stress and inflammation. Environ Int 136:105475

Article  CAS  PubMed  Google Scholar 

Ye Q, Zhang T, Mao JH (2020) Haze facilitates sensitization to house dust mites in children. Environ Geochem Health 42:2195–2203. https://doi.org/10.1007/s10653-019-00481-6

Article  CAS  PubMed  Google Scholar 

Yuan C-S, Lai C-S, Tseng Y-L, Hsu P-C, Lin C-M, Cheng F-J (2021) Repeated exposure to fine particulate matter constituents lead to liver inflammation and proliferative response in mice. Ecotoxicol Environ Saf 224:112636

Article  CAS  PubMed  Google Scholar 

Zhang S et al (2023) Mutagenicity of PM2.5 and ethnic susceptibility in Chengdu-Chongqing Economic Circle, China. Sci Total Environ 879:163022. https://doi.org/10.1016/j.scitotenv.2023.163022

Article  CAS  PubMed  Google Scholar 

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