Vaginal Progesterone for Preventing Preterm Birth and Adverse Perinatal Outcomes in Twin Gestations: A Systematic Review and Meta-analysis

Pregnancy Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, United States Department of Health and Human Services, Bethesda, MD and Detroit, MI (A.C.-A., R.R.); Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI (A.C.-A.); Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI (R.R.); Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI (R.R.); Fetal Medicine Research Institute, King’s College Hospital, London, United Kingdom (A.R., A.S., K.H.N.); Departamento de Obstetricia e Ginecologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil (M.L.B.); Maternal-Fetal Medicine Unit, Instituto Valenciano de Infertilidad, University of Valencia, Valencia, Spain (V.S.); Department of Pediatrics, Obstetrics, and Gynecology, University of Valencia, Valencia, Spain (V.S., A.P.); Departamento do Obstetricia e Ginecologia, Hospital do Servidor Publico Estadual Francisco Morato de Oliveira and School of Medicine, University of São Paulo, São Paulo, Brazil (E.D.F.); Department of Obstetrics and Gynecology, Zeynep Kamil Women and Children Diseases Education and Research Hospital, Istanbul, Turkey (E.C.); Department of Obstetrics, University Hospital La Fe, Valencia, Spain (A.P.); Office of Women’s Health, Integrative Biosciences Center, Wayne State University, Detroit, MI (S.S.H.); Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI (S.S.H.); and Department of Physiology, Wayne State University School of Medicine, Detroit, MI (S.S.H.)

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