Takehara T, Sakamoto N, Nishiguchi S, et al. Efficacy and safety of sofosbuvir-velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial. J Gastroenterol. 2019;54:87–95.
Article CAS PubMed Google Scholar
Suda G, Ogawa K, Morikawa K, et al. Treatment of hepatitis C in special populations. J Gastroenterol. 2018;53:591–605.
Article CAS PubMed PubMed Central Google Scholar
Carmona I, Cordero P, Ampuero J, et al. Role of assessing liver fibrosis in management of chronic hepatitis C virus infection. Clin Microbiol Infect. 2016;22:839–45.
Article CAS PubMed Google Scholar
Tahata Y, Hikita H, Mochida S, et al. Liver-related events after direct-acting antiviral therapy in patients with hepatitis C virus-associated cirrhosis. J Gastroenterol. 2022;57:120–32.
Article CAS PubMed Google Scholar
Tahata Y, Hikita H, Mochida S, et al. Posttreatment liver function, but not baseline liver function stratifies patient survival after direct-acting antiviral treatment in decompensated cirrhosis with hepatitis C virus. J Gastroenterol. 2023. https://doi.org/10.1007/s00535-023-02039-x.
Article PubMed PubMed Central Google Scholar
El-Sherif O, Jiang ZG, Tapper EB, et al. Baseline factors associated with improvements in decompensated cirrhosis after direct-acting antiviral therapy for hepatitis C virus infection. Gastroenterology. 2018;154:2111-21.e8.
Article CAS PubMed Google Scholar
Seko Y, Moriguchi M, Hara T, et al. Presence of varices in patients after hepatitis C virus eradication predicts deterioration in the FIB-4 index. Hepatol Res. 2019;49:473–8.
Article CAS PubMed Google Scholar
Mauro E, Crespo G, Montironi C, et al. Portal pressure and liver stiffness measurements in the prediction of fibrosis regression after sustained virological response in recurrent hepatitis C. Hepatology. 2018;67:1683–94.
Suzuki T, Matsuura K, Nagura Y, et al. Serum angiopoietin-2 levels predict regression of Mac-2 binding protein glycosylation isomer-based liver fibrosis after hepatitis C virus eradication by direct-acting antiviral agents. Hepatol Res. 2022;52:919–27.
Article CAS PubMed Google Scholar
Nagura Y, Suzuki T, Matsuura K, et al. Serum inducible protein 10 kDa/C-X-C motif chemokine 10 levels predict regression of M2BPGi-based liver fibrosis after hepatitis C virus eradication by direct-acting antiviral agents. Hepatol Res. 2024;54:32–42.
Article CAS PubMed Google Scholar
Gu J, Xu H, Chen Y, et al. MiR-223 as a regulator and therapeutic target in liver diseases. Front Immunol. 2022;13: 860661.
Article CAS PubMed PubMed Central Google Scholar
Hildonen S, Skarpen E, Halvorsen TG, et al. Isolation and mass spectrometry analysis of urinary extraexosomal proteins. Sci Rep. 2016;6:36331.
Article CAS PubMed PubMed Central Google Scholar
Xu H, Liao C, Zuo P, et al. Magnetic-based microfluidic device for on-chip isolation and detection of tumor-derived exosomes. Anal Chem. 2018;90:13451–8.
Article CAS PubMed Google Scholar
Zhang Y, Kim MS, Jia B, et al. Hypothalamic stem cells control ageing speed partly through exosomal miRNAs. Nature. 2017;548:52–7.
Article CAS PubMed PubMed Central Google Scholar
Tadokoro T, Morishita A, Masaki T. Diagnosis and therapeutic management of liver fibrosis by microRNA. Int J Mol Sci. 2021;22:8139.
Article CAS PubMed PubMed Central Google Scholar
Matsuura K, De Giorgi V, Schechterly C, et al. Circulating let-7 levels in plasma and extracellular vesicles correlate with hepatic fibrosis progression in chronic hepatitis C. Hepatology. 2016;64:732–45.
Article CAS PubMed Google Scholar
Matsuura K, Aizawa N, Enomoto H, et al. Circulating let-7 levels in serum correlate with the severity of hepatic fibrosis in chronic hepatitis C. Open Forum Infect Dis. 2018;5:ofy268.
Article PubMed PubMed Central Google Scholar
Babuta M, Szabo G. Extracellular vesicles in inflammation: focus on the microRNA cargo of EVs in modulation of liver diseases. J Leukoc Biol. 2022;111:75–92.
Article CAS PubMed Google Scholar
Yukawa H, Yamazaki S, Aoki K, et al. Co-continuous structural effect of size-controlled macro-porous glass membrane on extracellular vesicle collection for the analysis of miRNA. Sci Rep. 2021;11:8672.
Article CAS PubMed PubMed Central Google Scholar
Sasaki R, Yamasaki K, Abiru S, et al. Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein values predict the development of hepatocellular carcinoma among patients with chronic hepatitis c after sustained virological response. PLoS One. 2015;10: e0129053.
Article PubMed PubMed Central Google Scholar
Yamasaki K, Tateyama M, Abiru S, et al. Elevated serum levels of Wisteria floribunda agglutinin-positive human Mac-2 binding protein predict the development of hepatocellular carcinoma in hepatitis C patients. Hepatology. 2014;60:1563–70.
Article CAS PubMed Google Scholar
Xiao G, Yang J, Yan L. Comparison of diagnostic accuracy of aspartate aminotransferase to platelet ratio index and fibrosis-4 index for detecting liver fibrosis in adult patients with chronic hepatitis B virus infection: a systemic review and meta-analysis. Hepatology. 2015;61:292–302.
Johnson PJ, Berhane S, Kagebayashi C, et al. Assessment of liver function in patients with hepatocellular carcinoma: a new evidence-based approach-the ALBI grade. J Clin Oncol. 2015;33:550–8.
Ramsköld D, Luo S, Wang YC, et al. Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat Biotechnol. 2012;30:777–82.
Article PubMed PubMed Central Google Scholar
Kanda Y. Investigation of the freely available easy-to-use software “EZR” for medical statistics. Bone Marrow Transplant. 2013;48:452–8.
Article CAS PubMed Google Scholar
Setiawan VW, Rosen HR. Stratification of residual risk of HCC following HCV clearance with direct-acting antivirals in patients with advanced fibrosis and cirrhosis. Hepatology. 2020;72:1897–9.
Lemoinne S, Thabut D, Housset C, et al. The emerging roles of microvesicles in liver diseases. Nat Rev Gastroenterol Hepatol. 2014;11:350–61.
Article CAS PubMed Google Scholar
Schwarzenbach H, Nishida N, Calin GA, et al. Clinical relevance of circulating cell-free microRNAs in cancer. Nat Rev Clin Oncol. 2014;11:145–56.
Article CAS PubMed Google Scholar
Valadi H, Ekström K, Bossios A, et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9:654–9.
Article CAS PubMed Google Scholar
Arrese M, Eguchi A, Feldstein AE. Circulating microRNAs: emerging biomarkers of liver disease. Semin Liver Dis. 2015;35:43–54.
Article CAS PubMed Google Scholar
Kamerkar S, LeBleu VS, Sugimoto H, et al. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017;546:498–503.
Article CAS PubMed PubMed Central Google Scholar
Madeo M, Colbert PL, Vermeer DW, et al. Cancer exosomes induce tumor innervation. Nat Commun. 2018;9:4284.
Article PubMed PubMed Central Google Scholar
Liu F, Vermesh O, Mani V, et al. The exosome total isolation chip. ACS Nano. 2017;11:10712–23.
Article CAS PubMed PubMed Central Google Scholar
Shi L, Kuhnell D, Borra VJ, et al. Rapid and label-free isolation of small extracellular vesicles from biofluids utilizing a novel insulator based dielectrophoretic device. Lab Chip. 2019;19:3726–34.
Article CAS PubMed PubMed Central Google Scholar
Luo X, An M, Cuneo KC, et al. High-performance chemical isotope labeling liquid chromatography mass spectrometry for exosome metabolomics. Anal Chem. 2018;90:8314–9.
Article CAS PubMed PubMed Central Google Scholar
Yoshida M, Yukawa H, Hayashi K, et al. Clinical impact of bile-derived exosomal microRNAs as novel diagnostic and prognostic biomarkers for biliary tract cancers. Cancer Sci. 2023;114:295–305.
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