Albers HM, Dong A, van Meeteren LA, Egan DA, Sunkara M, van Tilburg EW, Schuurman K, van Tellingen O, Morris AJ, Smyth SS, Moolenaar WH, Ovaa H (2010) Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. Proc Natl Acad Sci U S A 107:7257–7262. https://doi.org/10.1073/pnas.1001529107
Article PubMed PubMed Central Google Scholar
Aoki J, Inoue A, Okudaira S (2008) Two pathways for lysophosphatidic acid production. Biochim Biophys Acta 1781:513–518. https://doi.org/10.1016/j.bbalip.2008.06.005
Article CAS PubMed Google Scholar
Arun P, Wilder DM, Morris AJ, Sabbadini R, Long JB (2023) Cerebrospinal fluid levels of lysophosphatidic acids can provide suitable biomarkers of blast-induced traumatic brain injury. J Neurotrauma. https://doi.org/10.1089/neu.2023.0087
Bitar L, Uphaus T, Thalman C, Muthuraman M, Gyr L, Ji H, Domingues M, Endle H, Groppa S, Steffen F, Koirala N, Fan W, Ibanez L, Heitsch L, Cruchaga C, Lee JM, Kloss F, Bittner S, Nitsch R, Zipp F, Vogt J (2022) Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke. Sci Transl Med 14:e0135. https://doi.org/10.1126/scitranslmed.abk0135
Botker HE, Hausenloy D, Andreadou I, Antonucci S, Boengler K, Davidson SM, Deshwal S, Devaux Y, Di Lisa F, Di Sante M, Efentakis P, Femmino S, Garcia-Dorado D, Giricz Z, Ibanez B, Iliodromitis E, Kaludercic N, Kleinbongard P, Neuhauser M, Ovize M, Pagliaro P, Rahbek-Schmidt M, Ruiz-Meana M, Schluter KD, Schulz R, Skyschally A, Wilder C, Yellon DM, Ferdinandy P, Heusch G (2018) Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection. Basic Res Cardiol 113:39. https://doi.org/10.1007/s00395-018-0696-8
Article CAS PubMed PubMed Central Google Scholar
Cai L, Fan G, Wang F, Liu S, Li T, Cong X, Chun J, Chen X (2017) Protective role for LPA3 in cardiac hypertrophy induced by myocardial infarction but not by isoproterenol. Front Physiol 8:356. https://doi.org/10.3389/fphys.2017.00356
Article PubMed PubMed Central Google Scholar
Canul-Sanchez JA, Hernandez-Araiza I, Hernandez-Garcia E, Llorente I, Morales-Lazaro SL, Islas LD, Rosenbaum T (2018) Different agonists induce distinct single-channel conductance states in TRPV1 channels. J Gen Physiol 150:1735–1746. https://doi.org/10.1085/jgp.201812141
Article CAS PubMed PubMed Central Google Scholar
Castrejon-Tellez V, Del Valle-Mondragon L, Perez-Torres I, Guarner-Lans V, Pastelin-Hernandez G, Ruiz-Ramirez A, Diaz-Juarez JA, Varela-Lopez E, Oidor-Chan VH, Vargas-Gonzalez A, Martinez-Memije R, Flores-Chavez P, Leon-Ruiz B, Arriaga-Carrillo S, Torres-Narvaez JC (2022) TRPV1 contributes to modulate the nitric oxide pathway and oxidative stress in the isolated and perfused rat heart during ischemia and reperfusion. Molecules 27:1031. https://doi.org/10.3390/molecules27031031
Article CAS PubMed PubMed Central Google Scholar
Chen H, Liu S, Liu X, Yang J, Wang F, Cong X, Chen X (2017) Lysophosphatidic acid pretreatment attenuates myocardial ischemia/reperfusion injury in the immature hearts of rats. Front Physiol 8:153. https://doi.org/10.3389/fphys.2017.00153
Article PubMed PubMed Central Google Scholar
Chen X, Yang XY, Wang ND, Ding C, Yang YJ, You ZJ, Su Q, Chen JH (2003) Serum lysophosphatidic acid concentrations measured by dot immunogold filtration assay in patients with acute myocardial infarction. Scand J Clin Lab Invest 63:497–503. https://doi.org/10.1080/00365510310003265
Article CAS PubMed Google Scholar
Cheng XY, Chen C, He SF, Huang CX, Zhang L, Chen ZW, Zhang Y (2019) Spinal NGF induces anti-intrathecal opioid-initiated cardioprotective effect via regulation of TRPV1 expression. Eur J Pharmacol 844:145–155. https://doi.org/10.1016/j.ejphar.2018.12.007
Article CAS PubMed Google Scholar
Communal C, Singh K, Pimentel DR, Colucci WS (1998) Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway. Circulation 98:1329–1334. https://doi.org/10.1161/01.cir.98.13.1329
Article CAS PubMed Google Scholar
Dohi T, Miyauchi K, Ohkawa R, Nakamura K, Kurano M, Kishimoto T, Yanagisawa N, Ogita M, Miyazaki T, Nishino A, Yaginuma K, Tamura H, Kojima T, Yokoyama K, Kurata T, Shimada K, Daida H, Yatomi Y (2013) Increased lysophosphatidic acid levels in culprit coronary arteries of patients with acute coronary syndrome. Atherosclerosis 229:192–197. https://doi.org/10.1016/j.atherosclerosis.2013.03.038
Article CAS PubMed Google Scholar
Dou M, Ma Z, Cheng X, Zou G, Xu Y, Huang C, Xiong W, He S, Zhang Y (2019) Intrathecal lentivirus-mediated RNA interference targeting nerve growth factor attenuates myocardial ischaemia-reperfusion injury in rat. Br J Anaesth 123:439–449. https://doi.org/10.1016/j.bja.2019.06.024
Article CAS PubMed Google Scholar
Dull MM, Stengel M, Ries V, Strupf M, Reeh PW, Kremer AE, Namer B (2022) Lysophosphatidic acid activates nociceptors and causes pain or itch depending on the application mode in human skin. Pain 163:445–460. https://doi.org/10.1097/j.pain.0000000000002363
Article CAS PubMed Google Scholar
Eichholtz T, Jalink K, Fahrenfort I, Moolenaar WH (1993) The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem J 291(Pt 3):677–680. https://doi.org/10.1042/bj2910677
Article CAS PubMed PubMed Central Google Scholar
Eisenhofer G, Friberg P, Rundqvist B, Quyyumi AA, Lambert G, Kaye DM, Kopin IJ, Goldstein DS, Esler MD (1996) Cardiac sympathetic nerve function in congestive heart failure. Circulation 93:1667–1676. https://doi.org/10.1161/01.cir.93.9.1667
Article CAS PubMed Google Scholar
Foreman RD, Garrett KM, Blair RW (2015) Mechanisms of cardiac pain. Compr Physiol 5:929–960. https://doi.org/10.1002/cphy.c140032
Gao Y, Song J, Chen H, Cao C, Lee C (2015) TRPV1 activation is involved in the cardioprotection of remote limb ischemic postconditioning in ischemia-reperfusion injury rats. Biochem Biophys Res Commun 463:1034–1039. https://doi.org/10.1016/j.bbrc.2015.06.054
Article CAS PubMed Google Scholar
Hausenloy DJ, Botker HE, Ferdinandy P, Heusch G, Ng GA, Redington A, Garcia-Dorado D (2019) Cardiac innervation in acute myocardial ischaemia/reperfusion injury and cardioprotection. Cardiovasc Res 115:1167–1177. https://doi.org/10.1093/cvr/cvz053
Article CAS PubMed PubMed Central Google Scholar
Hausenloy DJ, Yellon DM (2007) Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection. Heart Fail Rev 12:217–234. https://doi.org/10.1007/s10741-007-9026-1
Article CAS PubMed Google Scholar
Hayakawa K, Kurano M, Ohya J, Oichi T, Kano K, Nishikawa M, Uranbileg B, Kuwajima K, Sumitani M, Tanaka S, Aoki J, Yatomi Y, Chikuda H (2019) Lysophosphatidic acids and their substrate lysophospholipids in cerebrospinal fluid as objective biomarkers for evaluating the severity of lumbar spinal stenosis. Sci Rep 9:9144. https://doi.org/10.1038/s41598-019-45742-7
Article CAS PubMed PubMed Central Google Scholar
He S, Zambelli VO, Sinharoy P, Brabenec L, Bian Y, Rwere F, Hell RC, Stein Neto B, Hung B, Yu X, Zhao M, Luo Z, Wu C, Xu L, Svensson KJ, McAllister SL, Stary CM, Wagner NM, Zhang Y, Gross ER (2023) A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents. J Clin Invest 133:e163735. https://doi.org/10.1172/JCI163735
Article CAS PubMed PubMed Central Google Scholar
Hernandez-Resendiz S, Prakash A, Loo SJ, Semenzato M, Chinda K, Crespo-Avilan GE, Dam LC, Lu S, Scorrano L, Hausenloy DJ (2023) Targeting mitochondrial shape: at the heart of cardioprotection. Basic Res Cardiol 118:49. https://doi.org/10.1007/s00395-023-01019-9
Article PubMed PubMed Central Google Scholar
Heusch G (2015) Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning. Circ Res 116:674–699. https://doi.org/10.1161/CIRCRESAHA.116.305348
Article CAS PubMed Google Scholar
Heusch G (2017) Vagal cardioprotection in reperfused acute myocardial infarction. JACC Cardiovasc Interv 10:1521–1522. https://doi.org/10.1016/j.jcin.2017.05.063
Heusch G (2020) Myocardial ischaemia-reperfusion injury and cardioprotection in perspective. Nat Rev Cardiol 17:773–789. https://doi.org/10.1038/s41569-020-0403-y
Howard-Quijano K, Yamaguchi T, Gao F, Kuwabara Y, Puig S, Lundquist E, Salavatian S, Taylor B, Mahajan A (2021) Spinal cord stimulation reduces ventricular arrhythmias by attenuating reactive gliosis and activation of spinal interneurons. JACC Clin Electrophysiol 7:1211–1225. https://doi.org/10.1016/j.jacep.2021.05.016
Article PubMed PubMed Central Google Scholar
Jiang D, Ju W, Wu X, Zhan X (2018) Elevated lysophosphatidic acid levels in the serum and cerebrospinal fluid in patients with multiple sclerosis: therapeutic response and clinical implication. Neurol Res 40:335–339. https://doi.org/10.1080/01616412.2018.1446256
Article CAS PubMed Google Scholar
Juarez-Contreras R, Rosenbaum T, Morales-Lazaro SL (2018) Lysophosphatidic acid and ion channels as molecular mediators of pain. Front Mol Neurosci 11:462. https://doi.org/10.3389/fnmol.2018.00462
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