aUniversity of Sheffield

bDepartment of Gastroenterology & Liver Unit, Royal Hallamshire Hospital

cDivision of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK

Correspondence to Prof. Reena Sidhu, Consultant Gastroenterologist, Room P12, P Floor, Department of Gastroenterology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK. Tel: +114 2261180; e-mail: [email protected]