Concomitant Radiochemotherapy: Principles and Biological Foundations

Aupérin A, Le Péchoux C, Rolland E, Curran WJ, Furuse K, Fournel P, Belderbos J, Clamon G, Ulutin HC, Paulus R, Yamanaka T, Bozonnat MC, Uitterhoeve A, Wang X, Stewart L, Arriagada R, Burdett S, Pignon JP. Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer. J Clin Oncol. 2010;28:2181–90.

Article  PubMed  Google Scholar 

Denis F, Garaud P, Bardet E, Alfonsi M, Sire C, Germain T, Bergerot P, Rhein B, Tortochaux J, Calais G. Final results of the 94–01 French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma. J Clin Oncol. 2004;22:69–76.

Article  PubMed  Google Scholar 

Steel GG. Terminology in the description of drug-radiation interactions. Int J Radiat Oncol Biol Phys. 1979;5:1145–50.

Article  CAS  PubMed  Google Scholar 

Steel GG, Peckham MJ. Exploitable mechanisms in combined radiotherapy-chemotherapy: the concept of additivity. Int J Radiat Oncol Biol Phys. 1979;5(1):85–91.

Article  CAS  PubMed  Google Scholar 

Kinsella TJ, et al. Enhancement of X ray induced DNA damage by pre-treatment with halogenated pyrimidine analogs. Int J Radiat Oncol Biol Phys. 1987;13(5):733–9.

Article  CAS  PubMed  Google Scholar 

Gregoire V, et al. Radiosensitization of mouse sarcoma cells by fludarabine (F-ara-A) or gemcitabine (dFdC), two nucleoside analogues, is not mediated by an increased induction or a repair inhibition of DNA double-strand breaks as measured by pulsed-field gel electrophoresis. Int J Radiat Biol. 1998;73(5):511–20.

Article  CAS  PubMed  Google Scholar 

Choy H, et al. Investigation of taxol as a potential radiation sensitizer. Cancer. 1993;71(11):3774–8.

Article  CAS  PubMed  Google Scholar 

Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 1998;58(7):1408–16.

CAS  PubMed  Google Scholar 

Bush RS, et al. Definitive evidence for hypoxic cells influencing cure in cancer therapy. Br J Cancer Suppl. 1978;3:302–6.

CAS  PubMed  PubMed Central  Google Scholar 

Milas L, et al. Role of reoxygenation in induction of enhancement of tumor radioresponse by paclitaxel. Cancer Res. 1995;55(16):3564–8.

CAS  PubMed  Google Scholar 

Stephens TJ. Regeneration of tumors after cytotoxic treatment. In: Meyn RE, Withers HR, editors. Radiation biology in cancer research. New York: Raven Press; 1980.

Google Scholar 

Milas L, et al. Dynamics of tumor cell clonogen repopulation in a murine sarcoma treated with cyclophosphamide. Radiother Oncol. 1994;30(3):247–53.

Article  CAS  PubMed  Google Scholar 

Jaïn RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Sciences. 2005;307(5706):58–62.

Article  Google Scholar 

Bonner JA, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med. 2006;354(6):567–78.

Article  CAS  PubMed  Google Scholar 

Mazeron R, et al. Current state of knowledge regarding the use of antiangiogenic agents with radiation therapy. Cancer Treat Rev. 2011;37(6):476–86.

CAS  PubMed  Google Scholar 

Slotman GJ, et al. Preoperative simultaneously administered cis-platinum plus radiation therapy for advanced squamous cell carcinoma of the head and neck. Head Neck Surg. 1986;8:159–64.

Article  CAS  PubMed  Google Scholar 

Jeremic B, et al. Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial. J Clin Oncol. 2000;18:1458–64.

Article  CAS  PubMed  Google Scholar 

Marcu L, Bezak E, Olver I. Scheduling cisplatin and radiotherapy in the treatment of squamous cell carcinomas of the head and neck: a modelling approach. Phys Med Biol. 2006;51(15):3625–37.

Article  CAS  PubMed  Google Scholar 

Marcu L, van Doorn T, Olver I. Cisplatin and radiotherapy in the treatment of locally advanced head and neck cancer. Acta Oncol. 2003;42:315–25.

Article  CAS  PubMed  Google Scholar 

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