Docking, synthesis, and anticancer assessment of novel quinoline-amidrazone hybrids

1-(Piperazin-1-yl)-1-(2-(quinolin-6-yl)hydrazineylidene)propan-2-one (10a)

1-Morpholino-1-(2-(quinolin-6-yl)hydrazineylidene)propan-2-one (10b)

1-(2-(Quinolin-6-yl)hydrazineylidene)-1-thiomorpholinopropan-2-one (10c)

Ethyl-4-(2-oxo-1-(2-(quinolin-6-yl)hydrazineylidene)propyl)piperazine-1- carboxylate (10d)

1-(4’-(3’’-Hydroxyphenyl)piperazin-1-yl)-1-(2-(quinolin-6- yl)hydrazineylidene)propan-2-one (10e)

1-(4’-(4’’-Nitrosophenyl)piperazin-1-yl)-1-(2-(quinolin-6- yl)hydrazineylidene)propan-2-one (10f)

1-(4’-(2’’-Hydroxyphenyl)piperazin-1-yl)-1-(2-(quinolin-6-yl) hydrazineylidene) propan-2-one (10g)

1-(4’-(4’’-Chlorophenyl)piperazin-1-yl)-1-(2-(quinolin-6- yl)hydrazineylidene)propan-2-one (10h)

1-(4’-Phenylpiperazin-1-yl)-1-(2-(quinolin-6- yl)hydrazineylidene)propan-2-one (10i)

1-(4’-(4’’-Hydroxyphenyl)piperazin-1-yl)-1-(2-(quinolin-6- yl)hydrazono)propan-2-one (10j)

1-(4’-Phenylpiperazin-1-yl)-1-(2-(quinolin-6- yl)hydrazineylidene)propan-2-one (10k)

1-(4’-(pyridin-2-yl)piperazin-1-yl)-1-(2-(quinolin-6-yl)hydrazineylidene)propan-2-one (10l)

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