Kansara M, Teng MW, Smyth MJ, Thomas DM. Translational biology of osteosarcoma. Nat Rev Cancer. 2014;14(11):722–35.

Article  CAS  PubMed  Google Scholar 

Luetke A, Meyers PA, Lewis I, Juergens H. Osteosarcoma treatment—where do we stand? A state of the art review. Cancer Treat Rev. 2014;40(4):523–32.

Article  PubMed  Google Scholar 

Chen Y, Liu R, Wang W, Wang C, Zhang N, Shao X, He Q, Ying M. Advances in targeted therapy for osteosarcoma based on molecular classification. Pharmacol Res. 2021;169: 105684.

Article  CAS  PubMed  Google Scholar 

Shoaib Z, Fan TM, Irudayaraj JMK. Osteosarcoma mechanobiology and therapeutic targets. Br J Pharmacol. 2022;179(2):201–17.

Article  CAS  PubMed  Google Scholar 

Fu D, Shi Y, Liu J-B, Wu T-M, Jia C-Y, Yang H-Q, Zhang D-D, Yang X-L, Wang H-M, Ma Y-S. Targeting long non-coding RNA to therapeutically regulate gene expression in cancer. Mol Ther Nucleic Acids. 2020;21:712–24.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park E-G, Pyo S-J, Cui Y, Yoon S-H, Nam J-W. Tumor immune microenvironment lncRNAs. Brief Bioinform. 2022;23(1).

Nandwani A, Rathore S, Datta M. LncRNAs in cancer: regulatory and therapeutic implications. Cancer Lett. 2021;501:162–71.

Article  CAS  PubMed  Google Scholar 

Zhang Y, Liu Q, Liao Q. Long noncoding RNA: a dazzling dancer in tumor immune microenvironment. J Exp Clin Cancer Res. 2020;39(1):231.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pi Y-N, Qi W-C, Xia B-R, Lou G, Jin W-L. Long non-coding RNAs in the tumor immune microenvironment: biological properties and therapeutic potential. Front Immunol. 2021;12: 697083.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chai Y, Wu H-T, Liang C-D, You C-Y, Xie M-X, Xiao S-W. Exosomal lncRNA ROR1-AS1 derived from tumor cells promotes glioma progression via regulating miR-4686. Int J Nanomed. 2020;15:8863–72.

Article  CAS  Google Scholar 

Guo R, Zou B, Liang Y, Bian J, Xu J, Zhou Q, Zhang C, Chen T, Yang M, Wang H, et al. LncRNA RCAT1 promotes tumor progression and metastasis via miR-214-5p/E2F2 axis in renal cell carcinoma. Cell Death Dis. 2021;12(7):689.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang H, Meng Q, Qian J, Li M, Gu C, Yang Y. Review: RNA-based diagnostic markers discovery and therapeutic targets development in cancer. Pharmacol Ther. 2022;234: 108123.

Article  CAS  PubMed  Google Scholar 

Yang J, Liu F, Wang Y, Qu L, Lin A. LncRNAs in tumor metabolic reprogramming and immune microenvironment remodeling. Cancer Lett. 2022;543: 215798.

Article  CAS  PubMed  Google Scholar 

Lin Z-B, Long P, Zhao Z, Zhang Y-R, Chu X-D, Zhao X-X, Ding H, Huan S-W, Pan Y-L, Pan J-H. Long noncoding RNA KCNQ1OT1 is a prognostic biomarker and mediates CD8+ T cell exhaustion by regulating CD155 expression in colorectal cancer. Int J Biol Sci. 2021;17(7):1757–68.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhu S, Liu Y, Wang X, Wang J, Xi G. lncRNA SNHG10 promotes the proliferation and invasion of osteosarcoma via Wnt/β-catenin signaling. Mol Ther Nucleic Acids. 2020;22:957–70.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aiello I, Fedele MLM, Román F, Marpegan L, Caldart C, Chiesa JJ, Golombek DA, Finkielstein CV, Paladino N. Circadian disruption promotes tumor-immune microenvironment remodeling favoring tumor cell proliferation. Sci Adv. 2020;6(42).

Xuan W, Khan F, James CD, Heimberger AB, Lesniak MS, Chen P. Circadian regulation of cancer cell and tumor microenvironment crosstalk. Trends Cell Biol. 2021;31(11):940–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang C, Barnoud C, Cenerenti M, Sun M, Caffa I, Kizil B, Bill R, Liu Y, Pick R, Garnier L, et al. Dendritic cells direct circadian anti-tumour immune responses. Nature. 2023;614(7946):136–43.

Article  CAS  PubMed  Google Scholar 

Wang C, Lutes LK, Barnoud C, Scheiermann C. The circadian immune system. Sci Immunol. 2022;7(72):2465.

Article  Google Scholar 

Palomino-Segura M, Hidalgo A. Circadian immune circuits. J Exp Med. 2021;218(2).

Sancar A, Van Gelder RN. Clocks, cancer, and chronochemotherapy. Science. 2021;371(6524).

Hadadi E, Taylor W, Li X-M, Aslan Y, Villote M, Rivière J, Duvallet G, Auriau C, Dulong S, Raymond-Letron I, et al. Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice. Nat Commun. 2020;11(1):3193.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ortega-Campos SM, Verdugo-Sivianes EM, Amiama-Roig A, Blanco JR, Carnero A. Interactions of circadian clock genes with the hallmarks of cancer. Biochim Biophys Acta Rev Cancer. 2023;1878(3): 188900.

Article  CAS  PubMed  Google Scholar 

Fagiani F, Di Marino D, Romagnoli A, Travelli C, Voltan D, Di Cesare ML, Racchi M, Govoni S, Lanni C. Molecular regulations of circadian rhythm and implications for physiology and diseases. Signal Transduct Target Ther. 2022;7(1):41.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dong Z, Zhang G, Qu M, Gimple RC, Wu Q, Qiu Z, Prager BC, Wang X, Kim LJY, Morton AR, et al. Targeting glioblastoma stem cells through disruption of the circadian clock. Cancer Discov. 2019;9(11):1556–73.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pariollaud M, Ibrahim LH, Irizarry E, Mello RM, Chan AB, Altman BJ, Shaw RJ, Bollong MJ, Wiseman RL, Lamia KA. Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer. Sci Adv. 2022;8(39):eabo1123.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang S, Huang P, Dai H, Li Q, Hu L, Peng J, Jiang S, Xu Y, Wu Z, Nie H, et al. TIMELESS regulates sphingolipid metabolism and tumor cell growth through Sp1/ACER2/S1P axis in ER-positive breast cancer. Cell Death Dis. 2020;11(10):892.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang X, Han Y, Li J, Hong D, Xue Z, Huang H, Du Z, Hou Y, Li H, Li H, et al. Multi-omics analysis of copy number variations of RNA regulatory genes in soft tissue sarcoma. Life Sci. 2021;265: 118734.

Article  CAS  PubMed  Google Scholar 

Sun Q, Qin X, Zhao J, Gao T, Xu Y, Chen G, Bai G, Guo Z, Liu J. Cuproptosis-related LncRNA signatures as a prognostic model for head and neck squamous cell carcinoma. Apoptosis. 2023;28(1–2):247–62.

Article  CAS  PubMed  Google Scholar 

Shu L, Tang J, Liu S, Tao Y. Plasma cell signatures predict prognosis and treatment efficacy for lung adenocarcinoma. Cell Oncol (Dordr). 2023.

Beird HC, Bielack SS, Flanagan AM, Gill J, Heymann D, Janeway KA, Livingston JA, Roberts RD, Strauss SJ, Gorlick R. Osteosarcoma. Nat Rev Dis Primers. 2022;8(1):77.

Article  PubMed  Google Scholar 

Gill J, Gorlick R. Advancing therapy for osteosarcoma. Nat Rev Clin Oncol. 2021;18(10):609–24.

Article  PubMed  Google Scholar 

Chen Y, Cao J, Zhang N, Yang B, He Q, Shao X, Ying M. Advances in differentiation therapy for osteosarcoma. Drug Discov Today. 2020;25(3):497–504.

Article  CAS  PubMed  Google Scholar 

Ghafouri-Fard S, Shirvani-Farsani Z, Hussen BM, Taheri M. The critical roles of lncRNAs in the development of osteosarcoma. Biomed Pharmacother. 2021;135: 111217.

Article  CAS  PubMed  Google Scholar 

Dean DC, Shen S, Hornicek FJ, Duan Z. From genomics to metabolomics: emerging metastatic biomarkers in osteosarcoma. Cancer Metastasis Rev. 2018;37(4):719–31.

Article  CAS  PubMed  Google Scholar 

Quadros M, Momin M, Verma G. Design strategies and evolving role of biomaterial assisted treatment of osteosarcoma. Mater Sci Eng C Mater Biol Appl. 2021;121: 111875.

Article  CAS  PubMed  Google Scholar 

Chow T, Wutami I, Lucarelli E, Choong PF, Duchi S, Di Bella C. Creating in vitro three-dimensional tumor models: a guide for the biofabrication of a primary osteosarcoma model. Tissue Eng B Rev. 2021;27(5):514–29.

Article  Google Scholar 

Koritala BSC, Porter KI, Arshad OA, Gajula RP, Mitchell HD, Arman T, Manjanatha MG, Teeguarden J, Van Dongen HPA, McDermott JE, et al. Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans. J Pineal Res. 2021;70(3): e12726.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang C, Chen L, Sun L, Jin H, Ren K, Liu S, Qian Y, Li S, Li F, Zhu C, et al. BMAL1 collaborates with CLOCK to directly promote DNA double-strand break repair and tumor chemoresistance. Oncogene. 2023;42(13):967–79.

Article  CAS  PubMed  PubMed Central