Palmer JN, Messina JC, Biletch R, Grosel K, Mahmoud RA. A cross-sectional, population-based survey of U.S. adults with symptoms of chronic rhinosinusitis. Allergy Asthma Proc. 2019;40:48–56.

Article  PubMed  Google Scholar 

Albu S. Chronic rhinosinusitis—an update on epidemiology, pathogenesis and management. J Clin Med. 2020;9:2285.

Article  PubMed  PubMed Central  Google Scholar 

Laube BL. Devices for aerosol delivery to treat sinusitis. J Aerosol Med. 2007;20(Suppl 1):S5-17.

Article  CAS  PubMed  Google Scholar 

Rudmik L. Economics of chronic rhinosinusitis. Curr Allergy Asthma Rep. 2017;17:20.

Article  PubMed  Google Scholar 

Baumann I, Blumenstock G, Zalaman IM, Praetorius M, Klingmann C, et al. Impact of gender, age, and comorbidities on quality of life in patients with chronic rhinosinusitis. Rhinology. 2007;45:268–72.

PubMed  Google Scholar 

Jurlin L, Gregurić T, Baudoin T, Grgić MV, Pažanin L, et al. Cluster analysis of chronic rhinosinusitis suggests gender-based differences. ORL J Otorhinolaryngol Relat Spec. 2019;81:1–9.

Article  PubMed  Google Scholar 

Adams DR, Xu LJ, Vickery TW, Scangas GA, Bleier BS, et al. The impact of gender on long-term quality of life after sinus surgery for chronic rhinosinusitis. Laryngoscope. 2023. https://doi.org/10.1002/lary.30719.

Article  PubMed  Google Scholar 

Gill AS, Ashby S, Oakley GM, Steele TO, Menjivar D, et al. Comorbidities known to affect physical function negatively impact baseline health-related quality-of-life in patients with chronic rhinosinusitis. Am J Rhinol Allergy. 2022;36:25–32.

Article  PubMed  Google Scholar 

Jankowski R, Gallet P, Nguyen DT, Rumeau C. Chronic rhinosinusitis of adults: new definition, new diagnosis. Rev Prat. 2019;69:274–8.

PubMed  Google Scholar 

Othieno F, Schlosser RJ, Rowan NR, Storck KA, Mattos JL, et al. Taste impairment in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2018;8:783–9.

Article  PubMed  PubMed Central  Google Scholar 

Han P, Whitcroft KL, Fischer J, Gerber J, Cuevas M, et al. Olfactory brain gray matter volume reduction in patients with chronic rhinosinusitis. Int Forum Allergy Rhinol. 2017;7:551–6.

Article  PubMed  Google Scholar 

Lin S, Nie M, Wang B, Duan S, Huang Q, et al. Intrinsic brain abnormalities in chronic rhinosinusitis associated with mood and cognitive function. Front Neurosci. 2023;17:1131114.

Article  PubMed  PubMed Central  Google Scholar 

Huang SF, Lee TJ, Lin KL. Concomitant bilateral orbital and brain abscesses–unusual complications of pediatric rhinosinusitis. Chang Gung Med J. 2005;28:51–5.

PubMed  Google Scholar 

Ziegler A, Patadia M, Stankiewicz J. Neurological complications of acute and chronic sinusitis. Curr Neurol Neurosci Rep. 2018;18:5.

Article  PubMed  Google Scholar 

Whyte A, Boeddinghaus R. The maxillary sinus: physiology, development and imaging anatomy. Dentomaxillofac Radiol. 2019;48:20190205.

Article  PubMed  PubMed Central  Google Scholar 

Harbo G, Grau C, Bundgaard T, Overgaard M, Elbrønd O, et al. Cancer of the nasal cavity and paranasal sinuses. A clinico-pathological study of 277 patients. Acta Oncol. 1997;36:45–50.

Article  CAS  PubMed  Google Scholar 

Brzost J, Czerwaty K, Dżaman K, Ludwig N, Piszczatowska K, et al. Perspectives in therapy of chronic rhinosinusitis. Diagnostics. 2022;12:2301.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shrestha K, Wong E, Salati H, Fletcher DF, Singh N, et al. Liquid volume and squeeze force effects on nasal irrigation using volume of fluid modelling. Exp Comput Multiph Flow. 2022;4:445–64.

Article  Google Scholar 

Farrell NF, Klatt-Cromwell C, Schneider JS. Benefits and safety of nasal saline irrigations in a pandemic-washing COVID-19 away. JAMA Otolaryngol Head Neck Surg. 2020;146:787–8.

Article  PubMed  Google Scholar 

Verma RR, Verma R. Sinonasal irrigation after endoscopic sinus surgery—past to present and future. Indian J Otolaryngol Head Neck Surg. 2023;75:1–8.

Article  PubMed  Google Scholar 

Abdullah B, Periasamy C, Ismail R. Nasal irrigation as treatment in sinonasal symptoms relief: a review of its efficacy and clinical applications. Indian J Otolaryngol Head Neck Surg. 2019;71:1718–26.

Article  PubMed  Google Scholar 

Sansila K, Eiamprapai P, Sawangjit R. Effects of self-prepared hypertonic nasal saline irrigation in allergic rhinitis: a randomized controlled trial. Asian Pac J Allergy Immunol. 2020;38:200–7.

CAS  PubMed  Google Scholar 

Shi J, Tan L, Ye J, Hu L. Hypertonic saline and mannitol in patients with traumatic brain injury: a systematic and meta-analysis. Medicine. 2020;99:e21655.

Article  PubMed  PubMed Central  Google Scholar 

Salati H, Bartley J, White DE. Nasal saline irrigation—a review of current anatomical, clinical and computational modelling approaches. Respir Physiol Neurobiol. 2020;273:103320.

Article  PubMed  Google Scholar 

Salati H, Bartley J, Yazdi SG, Jermy M, White DE. Neti pot irrigation volume filling simulation using anatomically accurate in-vivo nasal airway geometry. Respir Physiol Neurobiol. 2021;284:103580.

Article  CAS  PubMed  Google Scholar 

Inthavong K, Shang Y, Wong E, Singh N. Characterization of nasal irrigation flow from a squeeze bottle using computational fluid dynamics. Int Forum Allergy Rhinol. 2020;10:29–40.

Article  PubMed  Google Scholar 

Siddiqui Z, Tahiri M, Gupta A, Kin Nam RH, Rachmanidou A. The management of paediatric rhinosinusitis. Int J Pediatr Otorhinolaryngol. 2021;147:110786.

Article  PubMed  Google Scholar 

Medikeri G, Javer A. Optimal management of allergic fungal rhinosinusitis. J Asthma Allergy. 2020;13:323–32.

Article  PubMed  PubMed Central  Google Scholar 

Bartier S, Coste A, Bequignon E. Management strategies for chronic rhinosinusitis with nasal polyps in adults. Rev Mal Respir. 2021;38:183–98.

Article  CAS  PubMed  Google Scholar 

Amjadimanesh H, Faramarzi M, Sadrizadeh S, Abouali O. Micro-particle deposition in maxillary sinus for various sizes of opening in a virtual endoscopic surgery. Exp Comput Multiph Flow. 2023;5:262–71.

Article  Google Scholar 

Alsaleh S, Manji J, Javer A. Optimization of the surgical field in endoscopic sinus surgery: an evidence-based approach. Curr Allergy Asthma Rep. 2019;19:8.

Article  PubMed  Google Scholar 

Li Y, Konuthula N, Humphreys IM, Moe K, Hannaford B, et al. Real-time virtual intraoperative CT in endoscopic sinus surgery. Int J Comput Assist Radiol Surg. 2022;17:249–60.

Article  PubMed  Google Scholar 

Zhao K, Craig JR, Cohen NA, Adappa ND, Khalili S, et al. Sinus irrigations before and after surgery—visualization through computational fluid dynamics simulations. Laryngoscope. 2016;126:E90-96.

Article  PubMed  Google Scholar 

Wu Z, Craig JR, Maza G, Li C, Otto BA, et al. Peak sinus pressures during sneezing in healthy controls and post-skull base surgery patients. Laryngoscope. 2020;130:2138–43.

Article  PubMed  Google Scholar 

Sun Q, Dong J, Zhang Y, Tian L, Tu J. Numerical study of the effect of nasopharynx airway obstruction on the transport and deposition of nanoparticles in nasal airways. Exp Comput Multiph Flow. 2022;4:399–408.

Article  Google Scholar 

Xi J, Lei LR, Zouzas W, April Si X. Nasally inhaled therapeutics and vaccination for COVID-19: developments and challenges. MedComm. 2021;2:569–86.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xi J. Development and challenges of nasal spray vaccines for short-term COVID-19 protection. Curr Pharm Biotechnol. 2022;23:1671–7.

Article  CAS  PubMed  Google Scholar 

Sélam JL. Inhaled insulin: Promises and concerns. J Diabetes Sci Technol. 2008;2:311–5.

Article  PubMed  PubMed Central  Google Scholar 

Djupesland PG, Skretting A, Winderen M, Holand T. Bi-directional nasal delivery of aerosols can prevent lung deposition. J Aerosol Med. 2004;17:249–59.

Article  CAS  PubMed  Google Scholar 

Xi J, Wang Z, Nevorski D, White T, Zhou Y. Nasal and olfactory deposition with normal and bidirectional intranasal delivery techniques: in vitro tests and numerical simulations. J Aerosol Med Pulm Drug Deliv. 2017;30:118–31.

Article  CAS  PubMed  Google Scholar 

Xi J, Wang Z, Si XA, Zhou Y. Nasal dilation effects on olfactory deposition in unilateral and bi-directional deliveries: in vitro tests and numerical modeling. Eur J Pharm Sci. 2018;118:113–23.

Article  CAS  PubMed