Objective Definition and Optimized Strategy for “Biologically Borderline Resectable” Colorectal Liver Metastases

Takamoto T, Hashimoto T, Ogata S et al (2013) Planning of anatomical liver segmentectomy and subsegmentectomy with 3-dimensional simulation software. Am J Surg 206:530–538

Article  PubMed  Google Scholar 

Takamoto T, Sano K, Hashimoto T et al (2018) Practical contribution of virtual hepatectomy for colorectal liver metastases: a propensity-matched analysis of clinical outcome. J Gastrointest Surg 22:2037–2044

Article  PubMed  Google Scholar 

Takamoto T, Mise Y, Satou S et al (2018) Feasibility of intraoperative navigation for liver resection using real-time virtual sonography with novel automatic registration system. World J Surg 42:841–848

Article  PubMed  Google Scholar 

Moazzam Z, Lima HA, Alaimo L et al (2022) Impact of tumor burden score on timing and patterns of recurrence after curative-intent resection of hepatocellular carcinoma. Surgery 172:1448–1455

Article  PubMed  Google Scholar 

Beppu T, Sakamoto Y, Hasegawa K et al (2012) A nomogram predicting disease-free survival in patients with colorectal liver metastases treated with hepatic resection: multicenter data collection as a Project Study for Hepatic Surgery of the Japanese Society of Hepato-Biliary-Pancreatic Surgery. J Hepatobiliary Pancreat Sci 19:72–84

Article  PubMed  Google Scholar 

Tempero MA, Malafa MP, Al-Hawary M et al (2021) Pancreatic adenocarcinoma, version 2.2021, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw 19:439–457

Article  CAS  PubMed  Google Scholar 

Ducreux M, Cuhna AS, Caramella C et al (2015) Cancer of the pancreas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 26(Suppl 5):v56-68

Article  PubMed  Google Scholar 

Versteijne E, van Dam JL, Suker M et al (2022) Neoadjuvant chemoradiotherapy versus upfront surgery for resectable and borderline resectable pancreatic cancer: long-term results of the dutch randomized PREOPANC trial. J Clin Oncol 40:1220–1230

Article  CAS  PubMed  Google Scholar 

Versteijne E, Vogel JA, Besselink MG et al (2018) Meta-analysis comparing upfront surgery with neoadjuvant treatment in patients with resectable or borderline resectable pancreatic cancer. Br J Surg 105:946–958

Article  CAS  PubMed  Google Scholar 

Sakamoto Y, Fujita S, Akasu T et al (2010) Is surgical resection justified for stage IV colorectal cancer patients having bilobar hepatic metastases?–an analysis of survival of 77 patients undergoing hepatectomy. J Surg Oncol 102:784–788

Article  PubMed  Google Scholar 

Mise Y, Hasegawa K, Satou S et al (2011) Venous reconstruction based on virtual liver resection to avoid congestion in the liver remnant. Br J Surg 98:1742–1751

Article  CAS  PubMed  Google Scholar 

Adam R, Laurent A, Azoulay D et al (2000) Two-stage hepatectomy: a planned strategy to treat irresectable liver tumors. Ann Surg 232:777–785

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schnitzbauer AA, Lang SA, Goessmann H et al (2012) Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings. Ann Surg 255:405–414

Article  PubMed  Google Scholar 

Andreou A, Knitter S, Schmelzle M et al (2021) Recurrence at surgical margin following hepatectomy for colorectal liver metastases is not associated with R1 resection and does not impact survival. Surgery 169:1061–1068

Article  PubMed  Google Scholar 

Beppu T, Sakamoto Y, Hasegawa K et al (2014) Optimal cut-off value for the number of colorectal liver metastases: a project study for hepatic surgery of the Japanese Society of Hepato-Biliary-Pancreatic Surgery. J Hepatobiliary Pancreat Sci 21:169–175

Article  PubMed  Google Scholar 

Eisenhauer EA, Therasse P, Bogaerts J et al (2009) New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 45:228–247

Article  CAS  PubMed  Google Scholar 

Nordlinger B, Sorbye H, Glimelius B et al (2008) Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet 371:1007–1016

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanemitsu Y, Shimizu Y, Mizusawa J et al (2021) Hepatectomy followed by mFOLFOX6 versus hepatectomy alone for liver-only metastatic colorectal cancer (JCOG0603): a phase ii or iii randomized controlled trial. J Clin Oncol 39:3789–3799

Article  CAS  PubMed  Google Scholar 

Bridgewater JA, Pugh SA, Maishman T et al (2020) Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre, randomised, controlled, phase 3 trial. Lancet Oncol 21:398–411

Article  CAS  PubMed  PubMed Central  Google Scholar 

Frühling P, Urdzik J, Isaksson B (2022) Chemotherapy in patients with a solitary colorectal liver metastasis—A nationwide propensity score matched study. Eur J Surg Oncol 48:2188–2194

Article  PubMed  Google Scholar 

Adam R, Delvart V, Pascal G et al (2004) Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. Ann Surg 240:644

Article  PubMed  PubMed Central  Google Scholar 

Tomasello G, Petrelli F, Ghidini M et al (2017) FOLFOXIRI plus bevacizumab as conversion therapy for patients with initially unresectable metastatic colorectal cancer: a systematic review and pooled analysis. JAMA Oncol 3:e170278–e170278

Article  PubMed  PubMed Central  Google Scholar 

Chua TC, Saxena A, Liauw W et al (2010) Systematic review of randomized and nonrandomized trials of the clinical response and outcomes of neoadjuvant systemic chemotherapy for resectable colorectal liver metastases. Ann Surg Oncol 17:492–501

Article  PubMed  Google Scholar 

Behrenbruch C, Prabhakaran S, Udayasiri DD et al (2021) Association between imaging response and survival following neoadjuvant chemotherapy in patients with resectable colorectal liver metastases: a cohort study. J Surg Oncol 123:1263–1273

Article  CAS  PubMed  Google Scholar 

Shida D, Tanabe T, Boku N et al (2019) Prognostic value of primary tumor sidedness for unresectable stage IV colorectal cancer: a retrospective study. Ann Surg Oncol 26:1358–1365

Article  PubMed  Google Scholar 

Kanemitsu Y, Shitara K, Mizusawa J et al (2021) Primary tumor resection plus chemotherapy versus chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases (JCOG1007; iPACS): a randomized clinical trial. J Clin Oncol 39:1098–1107

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ratti F, Cipriani F, Catena M et al (2014) Liver failure in patients treated with chemotherapy for colorectal liver metastases: role of chronic disease scores in patients undergoing major liver surgery. A case-matched analysis. Eur J Surg Oncol (EJSO) 40:1550–1556

Article  CAS  PubMed  Google Scholar 

Takamoto T, Hashimoto T, Sano K et al (2010) Recovery of liver function after the cessation of preoperative chemotherapy for colorectal liver metastasis. Ann Surg Oncol 17:2747–2755

Article  PubMed  Google Scholar 

Comments (0)

No login
gif