Antigen processing and presentation machinery
Gene signatures
Breast cancer
Risk assessment
Gene mutation
Immunotherapy
AbbreviationsICBimmune checkpoint blockade
PD-L1programmed cell death ligand 1
TNBCtriple negative breast cancer
TILstumor infiltrating lymphocytes
TAAtumor-associated antigen
TSAtumor-specific antigen
HLAhuman leukocyte antigen
APMantigen processing and presentation machinery
pAPCsprofessional antigen presenting cells
ssGSEAsingle-sample gene set enrichment analysis
RFSrecurrence-free survival
TCGAThe Cancer Genome Atlas
GEOgene expression Omnibus
MAFmutation annotation format
WGCNAweighted gene co-expression network analysis
NMFnon-negative matrix factorization
MSigDBmolecular signatures database
RSFrandom survival forest
Lassothe least absolute shrinkage and selection operator
APMrsAPM-related risk score
TIDEtumor immune dysfunction and exclusion
DEGsdifferentially expressed genes
APMisAPM-related immunotherapeutic response score
ROCreceiver operating characteristic
PFSprogression-free survival
CSScancer-specific survival
TAPantigen-processing-associated transporter protein
ERAPER-associated aminopeptidase
NSCLCnon-small-cell lung cancer
DCAdecision curve analysis
Data availabilityAll presented data and codes in this study are available from the corresponding author upon reasonable request.
© 2023 The Authors. Published by Elsevier Inc.
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