Advancing Treatment Frontiers: Radiofrequency Ablation for Small Renal Mass—Intermediate-Term Results

Rohit Kumar Singh

Department of Urology, Amrita Institute of Medical Sciences, Kochi, India


Manav Gideon

Department of Urology, Amrita Institute of Medical Sciences, Kochi, Kerala, India


Rohan Rajendran

Department of Urology, Amrita Institute of Medical Sciences, Kochi, India


Georgie Mathew

Department of Urology, Amrita Institute of Medical Sciences, Kochi, India


Kannan Nair

Department of Urology, Amrita Institute of Medical Sciences, Kochi, India


Keywords

radiofrequency ablation, small renal mass, Kidney, cancer, Postoperative complications

Abstract

Our study aims to discern the immediate and intermediate-term oncological outcomes of the patients with small renal mass and who were surgically unfit or were having a bilateral tumor and underwent radiofrequency ablation (RFA) of the mass. We retrospectively and prospectively analyzed the status of the patients who were diagnosed to have small renal masses and were biopsy-proven renal cell carcinoma (RCC) cases, who underwent RFA at our institute from the year 2013 to 2022. Patients were followed-up for 3 years. Data regarding complications were analyzed for all patients who underwent renal RFA along with the 3-year recurrence-free survival (RFS) rate. A total of 28 patients were eligible for the study based on our inclusion and exclusion criteria. Their renal function was recorded. They underwent RFA and were followed-up for a period of 3 years for RFS. Four patients out of the total had immediate complications, out of which two developed a hematoma. Three-year-follow-ups showed six recurrences, overall having 78.6% RFS. Post-procedural renal function was stable as documented by estimated glomerular filtration rate. Oncological results of RFA in patients with small renal masses who are surgically unfit are associated with a low risk of immediate and intermediate-term deterioration of renal function.

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