From the ∗Ophthalmologist, PGCM, Faculdade de Ciências Médica, Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil

†TIXUS–Technologic Core for Tissue Repair and Histocompatibility, Rio de Janeiro State University, Rio de Janeiro, Brazil

‡Discipline of Rheumatology, Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil

§Discipline of Ophthalmology, Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil

∥Discipline of Rheumatology, Hospital São Paulo–Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

¶Department of Ophthalmology, Instituto da Visão, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.

The authors declare no conflict of interest.

Data supporting the research publications are available upon request.

Author contribution: F.A.A. and L.C.P. contributed equally for design and implementation of this research. F.A.A. performed all ophthalmic evaluations supervised by K.M. and R.A.N. M.L.G.O., A.B.S.B., and A.W.S.S. contributed with patient clinical examination and evaluation. Immunogenetic analysis was performed by L.M. under L.C.P. supervision. L.C.P. and G.S. performed cluster analysis. R.A.L. conceived the original study concept and supervised the project. All authors participated in the development of the article.

This study received supporting grants from the Rio de Janeiro Rheumatology Society (SRRJ) and CAPES Brasil.

L.C.P. was awarded with grants from FAPERJ and CNPq.

Correspondence: Francisco Assis de Andrade, MD, Avenida Vieira Souto 86/104, 22.420-002 Rio de Janeiro, Brazil. E-mail: [email protected].

Supplemental digital content is available for this article. Direct URL citation appears in the printed text and is provided in the HTML and PDF versions of this article on the journal’s Web site (www.jclinrheum.com).