aDepartment of Intensive Care, Calderón Guardia Hospital, Universidad de Costa Rica, San José, Costa Rica

bDepartment of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium

Correspondence to Prof. Jean-Louis Vincent, MD, PhD, Department of Intensive Care, Erasme Hospital, Route de Lennik 808, Brussels, Belgium. E-mail: [email protected]