Author Contributions: Conception and design: I.S.-G. and A.H. Experiments: M.L., L.A., E.D., M.-L.F.-M., K.L.-T., and N.H. Analysis and interpretation: M.L., L.A., E.D., L.J., I.S.-G., and A.H. Drafting the manuscript and revision for important intellectual content: M.L., S.C., A.H., A.E., C.D., L.J., I.S.-G., and A.H.