Correspondence to: Nigel Mackman, PhD, Department of Medicine, 116 Manning Drive, 8004B Mary Ellen Jones Building, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599. Email

E-mail Address: [email protected]

https://orcid.org/0000-0002-9170-7700

UNC Blood Research Center, Division of Hematology, Department of Medicine, University of North Carolina at Chapel Hill.