Atopic dermatitis (AD) is one of the most common debilitating inflammatory skin diseases and often results in lifelong burdens for affected patients. Staphylococcus aureus (S. aureus) colonization has been found in the lesional skin of a majority of AD patients and can exacerbate the inflammatory responses [ [1] Geoghegan J.A. Irvine A.D. Foster T.J. Staphylococcus aureus and atopic dermatitis: a complex and evolving relationship.

Trends Microbiol. 2018; 26: 484-497

]. However, how S. aureus colonization contributes to chronic itch, one of the hallmark features of AD, is unknown.