The aim of this article is to discuss the sequelae of a missing tooth from normal series of dental arch and the importance of cone beam computed tomography (CBCT) in diagnosis and treatment planning in such cases. We also correlate the position of an impacted maxillary premolar as seen on panoramic radiography with CBCT. Routine imaging modalities like intraoral periapical, occlusal, and panoramic view often give inadequate information which can be misleading to the surgeon. Exact location of an impacted/missing tooth and its relation to dental and vital structures which was previously a challenge to assess by the clinician, can now be very well interpreted with CBCT. In this report, a case of impacted maxillary premolar is highlighted with its image on the panoramic radiograph, its exact location/position on CBCT, and how surgical removal was accomplished.