This month's cover highlights the article DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging by Sara Sepe, Francesca Rossiello, Fabrizio d’Adda di Fagagna and colleagues. The cover shows the SARS‐CoV‐2 virus in the center that when it is at a crossroad, chooses the shorter path, which represents the short telomere typical of aged individuals who express higher levels of the ACE2 receptor. (Scientific image by SciStories LLC ( scistories.com ). Cover concept by Ilaria Rosso, IFOM Foundation‐FIRC Institute of Molecular Oncology Foundation, Milan, Italy.)