EVAR – preliminary results from a single-center experience of a Mediterranean city: case report


 Table of Contents   CASE REPORT Year : 2021  |  Volume : 40  |  Issue : 2  |  Page : 738-742

EVAR – preliminary results from a single-center experience of a Mediterranean city: case report

Naga Ahmad R1, Ali Badra2
1 Alexandria Vascular Unit, Alexandria University, Egypt
2 Centre Hospitalier Universitaire De Brest, Hôpital de la Cavale Blanche, France

Date of Submission08-Feb-2021Date of Acceptance07-Mar-2021Date of Web Publication12-Oct-2021

Correspondence Address:
MD Naga Ahmad R
Alexandria Vascular Unit, Alexandria University, Zip Code 21519
Egypt
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Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/ejs.ejs_41_21

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Abdominal aortic aneurysm prevalence is estimated between 4 and 8% in screening programs, predominantly in males. The risk of rupture is directly proportionate to the size of the aneurysm; thus, prophylactic repair is justifiable. The three chief randomized trials comparing Endovascular Aneurysm Repair (EVAR) with conventional repair of abdominal aortic aneurysm have all shown a benefit of EVAR with respect to 30-day operative mortality and these results have been reinforced by data from large registries. Therefore, endovascular repair is now a common treatment option that offers a less-invasive alternative to standard surgical repair with the likely reduced hospitalization, morbidity, and mortality. In this work, we report the short-term results of six cases treated by Thoracic Endovascular Aneurysm Repair (TEVAR)/EVAR at Alexandria Vascular Center.

Keywords: abdominal aortic aneurysm, EVAR, thoraco-abdominal aneurysm


How to cite this article:
Ahmad R N, Badra A. EVAR – preliminary results from a single-center experience of a Mediterranean city: case report. Egypt J Surg 2021;40:738-42
How to cite this URL:
Ahmad R N, Badra A. EVAR – preliminary results from a single-center experience of a Mediterranean city: case report. Egypt J Surg [serial online] 2021 [cited 2021 Oct 13];40:738-42. Available from: http://www.ejs.eg.net/text.asp?2021/40/2/738/327997   Introduction Top

Abdominal aortic aneurysm (AAA) prevalence is estimated between 4 and 8% in screening programs, predominantly in males [1],[2]. The risk of rupture is directly proportionate to the size of the aneurysm; thus, prophylactic repair is justifiable [3]. The three chief randomized trials comparing Endovascular Aneurysm Repair (EVAR) with open repair have all shown a benefit of EVAR with respect to 30-day operative mortality [4],[5],[6].

In this work, we report the short-term (1 year) results of six cases treated by Thoracic Endovascular Aneurysm Repair (TEVAR)/EVAR at Alexandria Vascular Center in a 3-year period. The objective of the study is to evaluate the outcome of a nowadays-well-established procedure performed at a low-volume center to propose recommendations that will aid in delivering better service for Egyptian patients with AAA.

  Case report Top

Case 1

A 62-year-old male patient who was hypertensive, smoker, diabetic, and had Coronary Artery Bypass Graft (CABG) procedure before. He had a 6.5-cm infrarenal AAA without iliac involvement. He had a straight tubular Zenith Flex Cook device (COOK Medical, Bloomington, Indiana, USA) implanted. Upon extraction of the sheath, the common femoral artery ruptured, this was managed successfully by interposition-vein bypass. His follow-up Multislice Computed Tomography Angiography (MCTA) showed type-II endoleak that persisted in the 6-month MCTA, however, after 1 year, it spontaneously disappeared.

Case 2

A 78-year-old male patient who was a smoker and suffered from bronchial asthma and ischemic heart disease. He had an 8.3-cm infrarenal aorto-bi-iliac AAA. He had a conical angulated–tortuous neck (55°), splayed left Common Iliac Artery (CIA), and Pelvic Artery Index of 1.6 [7]. A Gore C3 Excluder stent graft (W.L. Gore and Associates, Flagstaff, Arizona, USA) was used, through a ballerina technique. First, MCTA 1 month postoperatively showed mild type-II endoleak, this has spontaneously resolved 1 year later. Figure 1a–c shows case 2.

Figure 1 (A) Case 2: 8.3 cm infrarenal aorto-bi-iliac AAA with a conical angulated neck. (B) MCTA 1 month postoperatively: mild type-II endoleak. (C) MCTA 12 months postoperatively: type-II endoleak spontaneously resolved.

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Case 3

A 66-year-old male patient who was diabetic, smoker, and suffered from ischemic heart disease. He had a straight tubular Zenith Flex Cook device graft implanted for his 7.8-cm infrarenal AAA (without iliac involvement). He had acute common femoral artery thrombosis toward the end of the procedure, this was treated immediately by successful thrombectomy. MCTA at 6 and 12 months showed no endoleaks.

Case 4

A 78-year-old male patient with a history of peptic ulcer and smoking. He presented with a 7.2-cm thoracic aneurysm with a concomitant 5.9-cm infrarenal AAA. TEVAR using Cook TX2 endograft device (COOK Medical) was used for his thoracic part and aorto-bi-iliac Zenith Flex for the abdominal extension. Notably, this was the longest procedure done (225 min) with a total radiation-exposure time of 110 min and 480 ml of contrast was used. His follow-up MCTA 1 month later was fine, however, a year later, it showed an asymptomatic type-I endoleak from the distal end of the TEVAR. He was 79 years old at that time and was not keen on any further intervention, thus, he was advised to repeat the MCTA in 6-month time. [Figure 2]a–e shows case 4.

Figure 2 Case 4: 7.2 cm thoracic aneurysm with a concomitant 5.9 cm. (A) TEVAR using Cook (TX2 endograft) and EVAR (Zenith FLEX). (B) Thoracic part. (C) Abdominal part. (D) 1 year later, showing type-I endoleak from the distal end of the TEVAR. (E) Endoleak evident in reconstruction.

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Case 5

A 69-year-old male patient, who is known to be a smoker and hypertensive. He had a 7.4-cm infrarenal AAA treated by Medtronic Endurant II device (Medtronic Cardiovascular, Santa Rosa, California, USA). The graft used was an aorto-bi-iliac stent with bilateral iliac extensions. His follow-up MCTA after 1 year showed no complications. [Figure 3] a–c shows case 5.

Figure 3 Case 5: 7.4-cm infrarenal AAA treated by Medtronic Endurant II. (A) MCTA after 1 year, main body. (B) MCTA after 1 year, 2 limbs. (C) Aorto-bi-iliac stent with bilateral iliac extensions.

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Case 6

A 58-year-old gentleman who had hypertension, migraine, and a history of renal stones. He presented with an 8.9-cm infrarenal AAA. He had an aorto-bi-iliac Cook device used. Postoperatively, he had groin lymphorrhea and fever of unknown origin. His MCTA after 1 month showed type-II endoleak that was not evident on further studies.

  Discussion Top

This series included six men who were treated by TEVAR/EVAR. None of the cases had suprarenal extension apart from case 4 who had an associated thoracic aneurysm. None of the cases needed conversion to open surgery, and there were no mortalities related to the aneurysm management. Primary technical success was achieved in all cases. Two cases needed adjunctive surgical maneuvers to accomplish clinical success. No clinical failure was experienced in any of the cases.

Two of our early cases with AAA without iliac involvement had straight tubular grafts used. Although their MCTA after 1 year did not show type-I endoleak, we believe that this short period of follow-up is not sufficient to justify deployment of endografts in such a manner for the reason that future dilatation of the distal neck is expected to occur, hence the development of type-I endoleak. Three of the cases had type-II endoleak upon completion of the procedure and were left for follow-up. None of them needed repair, and by 1 year, all of them had spontaneously resolved. In practice, type-II endoleak is the most common type encountered and is responsible for most reinterventions [8]. However, researchers have recently been suggesting a low threshold for interventions for it. Walker et al. [9] studied 474 cases having type-II endoleaks. They found no aneurysm ruptures related to any of the type-II endoleaks. Furthermore, there was no difference in all-cause mortality or aneurysm-related mortality in cases that had a type-II endoleak-related sac growth who had reintervention and those in whom the type-II endoleak was not treated.

Unfortunately, there is no screening-program detection for AAA in Egypt. The result is that most AAAs operated on are large in size presenting in older ages. Adding to the complexity of the matter is that AAA intervention is considered a prophylactic procedure to guard against rupture, that is, most patients are often asymptomatic. Thus, patients’ counseling is often challenging when explaining the urgency, cost, and risk of the procedure.

In conclusion, this small series sheds the light on how infrequent EVAR is carried out at our unit. Thus, we recommend vascular units in Egypt looking forward to manage patients with AAA to adopt patients’ and internists’ awareness campaigns to increase the referral rate. Also, simulator training for vascular trainees is essential to improve their learning curves. Moreover, centralization of the EVAR service is mandatory, otherwise resources and knowledge will be dispersed. Furthermore, multidisciplinary team meetings are important to be carried out routinely to discuss management plans for every case. Last, endovascular instruments to treat endoleaks and ruptures should be made available on-shelf in every vascular cath-lab.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 

  References Top
1.Lindholt J, Juul S, Fasting H, Henneberg E. Screening for abdominal aortic aneurysms: single centre randomised controlled trial. BMJ 2005; 330:750.  Back to cited text no. 1
    2.Ashton H, Gao L, Kim L, Druce P, Thompson S, Scott R. Fifteen-year follow-up of a randomized clinical trial of ultrasonographic screening for abdominal aortic aneurysms. Br J Surg 2007; 94:696.  Back to cited text no. 2
    3.Oliver-Williams C, Sweeting M, Turton G, Parkin D, Cooper D, Rodd C et al. Lessons learned about prevalence and growth rates of abdominal aortic aneurysms from a 25-year ultrasound population screening programme. Br J Surg 2018; 10:68.  Back to cited text no. 3
    4.EVAR Trial Participants. Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: randomised controlled trial. Lancet 2004; 36:843–848.  Back to cited text no. 4
    5.The United Kingdom EVAR Trial Investigators. Endovascular repair of aortic aneurysm in patients physically ineligible for open repair. N Engl J Med 2010; 362:1872-1880.  Back to cited text no. 5
    6.Lederle FA, Freischlag JA, Kyriakides TC, Padberg FT, Matsumura JS, Kohler TR et al. Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial. JAMA 2009; 30:1535–1542.  Back to cited text no. 6
    7.Chaikof E, Dalman R, Eskandari M, Jackson B, Lee W, Mansour M et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg 2018; 28:67–68.  Back to cited text no. 7
    8.Al-Jubouri M, Comerota AJ, Thakur S, Thakur S, Aziz F, Wanjiku S et al. Reintervention after EVAR and open surgical repair of AAA: a 15-year experience. Ann Surg 2013; 258:652–657.  Back to cited text no. 8
    9.Walker J, Tucker L, Goodney P, Candell L, Hua H, Okuhn S et al. Type II endoleak with or without intervention after endovascular aortic aneurysm repair does not change aneurysm-related outcomes despite sac growth. J Vasc Surg 2015; 62:551–561.  Back to cited text no. 9
    
  [Figure 1], [Figure 2], [Figure 3]

 

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