The Role of Psilocybin-Assisted Psychotherapy to Support Patients With Cancer: A Critical Scoping Review of the Research

Agin-Liebes, G. I., Malone, T., Yalch, M. M., Mennenga, S., Ponté, K. L., Guss, J., Bossis, A. P., Grigsby, J., Fischer, S., Ross, S. (2020). Long-term follow-up of psilocybin-assisted psychotherapy for psychiatric and existential distress in patients with life-threatening cancer. Journal of Psychopharmacology, 34(2), 155-166. https://doi.org/10.1177/0269881119897615
Google Scholar | SAGE Journals | ISI Arksey, H., O’Malley, L. (2005). Scoping studies: Towards a methodological framework. International Journal of Social Research Methodology, 8(1), 19-32. https://doi.org/10.1080/1364557032000119616
Google Scholar | Crossref Bauereiß, N., Obermaier, S., Özünal, S. E., Baumeister, H. (2018). Effects of existential interventions on spiritual, psychological, and physical well-being in adult patients with cancer: Systematic review and meta-analysis of randomized controlled trials. Psycho-Oncology, 27(11), 2531-2545. https://doi.org/10.1002/pon.4829
Google Scholar | Crossref | Medline Belser, A. B., Agin-Liebes, G., Swift, T. C., Terrana, S., Devenot, N., Friedman, H. L., Guss, J., Bossis, A., Ross, S. (2017). Patient experiences of psilocybin-assisted psychotherapy: An interpretative phenomenological analysis. Journal of Humanistic Psychology, 57(4), 354-388. https://doi.org/10.1177/0022167817706884
Google Scholar | SAGE Journals | ISI Bossis, A. P. (2021). Psilocybin, spirituality, and palliative care: Research and implications. Alternative and Complementary Therapies, 27(1), 14-17. https://doi.org/10.1089/act.2020.29309.apb
Google Scholar | Crossref Brant, J. M., Silbermann, M. (2021). Global perspectives on palliative care for cancer patients: Not all countries are the same. Current Oncology Reports, 23, 60. https://doi.org/10.1007/s11912-021-01044-8
Google Scholar | Crossref | Medline Byock, I. (2018). Taking psychedelics seriously. Journal of Palliative Medicine, 24(4), 417-421. https://doi.org/10.1089/jpm.2017.0684
Google Scholar | Crossref California Institute for Integral Studies . (2021). Center for Psychedelic Therapies and Research. Retrieved from https://www.ciis.edu/research-centers/center-for-psychedelic-therapies-and-research
Google Scholar Denis-Lalonde, D. (2020). Emerging psychedelic-assisted therapies: Implications for nursing practice. Journal of Mental Health and Addiction Nursing, 4(1), e1-e13. https://doi.org/10.22374/jmhan.v4i1.40
Google Scholar | Crossref Doyle, R. (2012). Healing with plant intelligence: A report from Ayahuasca. Anthropology of Consciousness, 23(1), 28-43. https://doi.org/10.1111/j.1556-3537.2012.01055.x
Google Scholar | Crossref Flanigan, M., Wyatt, G., Lehto, R. H. (2019). Perspectives on pain and spiritual quality of life in advanced breast cancer: A scoping review. Pain Management Nursing, 20(5), 432-443. https://doi.org/10.1016/j.pmn.2019.04.002
Google Scholar | Crossref | Medline Grassi, L., Spiegel, D., Riba, M. (2017). Advancing psychosocial care in cancer patients. F1000Research, 6, 2083. https://doi.org/10.12688/f1000research.11902.1
Google Scholar | Crossref | Medline Griffiths, R. R., Johnson, M. W., Carducci, M. A., Umbricht, A., Richards, W. A., Richards, B. D., Cosimano, M. P., Klinedinst, M. A. (2016). Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. Journal of Psychopharmacology, 30(12), 1181-1197. https://doi.org/10.1177/0269881116675513
Google Scholar | SAGE Journals | ISI Griffiths, R. R., Johnson, M. W., Richards, W. A., Richards, B. D., Jesse, R., MacLean, K. A., Barrett, F. S., Cosimano, M. P., Klinedinst, M. A. (2018). Psilocybin-occasioned mystical-type experience in combination with meditation and other spiritual practices produces enduring positive changes in psychological functioning and in trait measures of prosocial attitudes and behaviors. Journal of Psychopharmacology, 32(1), 49-69. https://doi.org/10.1177/0269881117731279
Google Scholar | SAGE Journals | ISI Grob, C. S., Danforth, A. L., Chopra, G. S., Hagerty, M., McKay, C. R., Halberstad, A. L., Greer, G. R. (2011). Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer. Archives of General Psychiatry, 68(1), 71-78. https://doi.org/10.1001/archgenpsychiatry.2010.116
Google Scholar | Crossref | Medline Johnson, R., Hauser, J., Emanuel, L. (2021). Toward a clinical model for patient spiritual journeys in supportive and palliative care: Testing a concept of human spirituality and associated recursive states. Palliative and Supportive Care, 19(1), 28-33. https://doi.org/10.1017/S1478951520000607
Google Scholar | Crossref | Medline Karlsson, M., Friberg, F., Wallengren, C., Ohlen, J. (2014). Meanings of existential uncertainty and certainty for people diagnosed with cancer and receiving palliative treatment: A life-world phenomenological study. BMC Palliative Care, 13, 28. https://doi.org/10.1186/1472-684X-13-28
Google Scholar | Crossref | Medline Kast, E. (1966). LSD and the dying patient. The Quarterly, 26(2), 80-87.
Google Scholar Kurland, A., Grof, S., Phanke, W., Goodman, L. (1972). Psychedelic drug assisted psychotherapy in patients with terminal cancer. In K. Goldberg, S. Malitz, & A. H. Kutscher (Eds.), Psychopharmacological Agents in the Terminally Ill and Bereaved (pp. 86-133). New York & London: Columbia University Press.
Google Scholar Lehto, R., Miller, S. E., Flanigan, M., Wyatt, G. (2018). Mental health in patients with advanced cancer at the end of life: Evaluation of evidence and future directions. Expert Review of Quality of Life in Cancer Care, 3(2-3), 73-94. https://doi.org/10.1080/23809000.2018.1483192
Google Scholar | Crossref Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., Moher, D. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration. Journal of Clinical Epidemiology, 151(4), e1-e34. https://doi.org/10.1016/j.jclinepi.2009.06.006
Google Scholar | Crossref Malone, T. C., Mennenga, S. E., Guss, J., Podrebarac, S. K., Owens, L. T., Bossis, A. P., Belser, A. B., Agin-Liebes, G., Bogenschutz, M. P., Ross, S. (2018). Individual experiences in four cancer patients following psilocybin-assisted psychotherapy. Frontiers in Pharmacology, 9, 256. https://doi.org/10.3389/fphar.2018.00256
Google Scholar | Crossref | Medline McCorvy, J. D., Olsen, R. H. J., Roth, B. L. (2016). Psilocybin for depression and anxiety associated with life-threatening illnesses. Journal of Psychopharmacology, 30(12), 1209-1210. https://doi.org/10.1177/0269881116675771
Google Scholar | SAGE Journals | ISI Nichols, D. E. (2020). Psilocybin: From ancient magic to modern medicine. The Journal of Antibiotics: Springer Nature, 73, 679-686. https://doi.org/10.1038/s41429-020-0311-8
Google Scholar | Crossref | Medline Organization of Psychedelic and Entheogenic Nurses . (2020). Retrieved from https://www.openurses.org/
Google Scholar Penn, A. (2021). Psychedelic-assisted therapy: Emerging treatments in mental health disorders. American Journal of Nursing, 121(6), 34-40. https://doi.org/10.1097/01.NAJ.0000753464.35523.29
Google Scholar | Crossref | Medline Penn, A., Phelps, J., Rosa, W., Watson, J. (2021). Psychedelic-assisted psychotherapy practices and human caring science: Toward a care-informed model of treatment. Journal of Humanistic Psychology [e-pub], 1-26. https://doi.org/10.1177/00221678211011013
Google Scholar | SAGE Journals Reed, P. G. (2018). Theory of self-transcendence. In Smith, M. J., Liehr, P. R. (Eds.), Middle range theory for nursing (4th ed., pp. 119-145). Springer Publishing Company.
Google Scholar | Crossref Rosa, W. E., Dorsen, C., Penn, A. (2020). Fostering nurse engagement in psychedelic-assisted therapies for patients with serious illness. Journal of Palliative Medicine, 23(10), 1288-1289. https://doi.org/10.1089/jpm.2020.0241
Google Scholar | Crossref | Medline Rosa, W. E., Hope, S., Matzo, M. (2019). Palliative nursing and sacred medicine: A holistic stance on entheogens, healing, and spiritual care. Journal of Holistic Nursing, 37(1), 100-106. https://doi.org/10.1177/0898010118770302
Google Scholar | SAGE Journals | ISI Ross, S., Agin-Liebes, G., Lo, S., Zeigman, R., Ghazal, L., Benville, J., Corso, S. F., Bjerre Real, C., Guss, J., Bossis, A., Mennenga, S. (2021). Acute and sustained reductions in loss of meaning and suicidal ideation following psilocybin-assisted psychotherapy for psychiatric and existential distress in life-threatening cancer. ACS Pharmacology & Translational Science, 4(2), 553-562. https://doi.org/10.1021/acsptsci.1c00020
Google Scholar | Crossref | Medline Ross, S., Bossis, A., Guss, J., Agin-Liebes, G., Malone, T., Cohen, B., Mennenga, S., Belser, A., Kalliontzi, K., Babb, J., Su, Z., Corby, P., Schmidt, B. L. (2016). Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: A randomized controlled trial. Journal of Psychopharmacology, 30(12), 1165-1180. https://doi.org/10.1177/0269881116675512
Google Scholar | SAGE Journals | ISI Schultes, R., Hoffman, A. (1979). Plants of the Gods. Alfred Van der Marck Editions.
Google Scholar Swift, T. C., Belser, A. B., Agin-Liebes, G., Devenot, N., Terrana, S., Friedman, H. L., Guss, J., Bossis, A., Ross, S. (2017). Cancer at the dinner table: Experiences of psilocybin-assisted psychotherapy for the treatment of cancer-related distress. Journal of Humanistic Psychology, 57(5), 488-519. https://doi.org/10.1177/0022167817715966
Google Scholar | SAGE Journals | ISI Tricco, A., Lillie, E., Zarin, W., O’Brien, K., Colquhoun, H., Levac, D., Moher, D., Peters, M. D. J., Horsley, T., Weeks, L., Hempel, S., Akl, E. A., Chang, C., McGowan, J., Stewart, L., Hartling, L., Aldcroft, A., Wilson, M. G., Garritty, C., …, Straus, S. (2018). PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine, 169(7), 467-473. https://doi.org/10.7326/M18-0850
Google Scholar | Crossref | Medline Watts, R., Day, C., Krzanowski, J., Nutt, D., Carhart-Harris, R. (2017). Patients’ accounts of increased “connectedness” and “acceptance” after psilocybin for treatment-resistant depression. Journal of Humanistic Psychology, 57(5), 520-564. https://doi.org/10.1177/0022167817709585
Google Scholar | SAGE Journals | ISI Zhai, J., Newton, J., Copnell, B. (2019). Posttraumatic growth experiences and its contextual factors in women with breast cancer: An integrative review. Health Care Women International, 40(5), 554-580. https://doi.org/10.1080/07399332.2019.1578360
Google Scholar | Crossref | Medline

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