Aamir MM, Ali E, Hamouda M, Mourad F (2015) Prevalence of multidrug resistant bacteria causing late-onset neonatal sepsis. Int J Curr Microbiol App Sci 4:172–190

CAS  Google Scholar 

Abate BB, Kasie AM, Kassaw M, Getu MA (2019) Neonatal sepsis and its associated factors in East Africa: a systematic review and meta-analysis

Adhikari NK, Fowler RA, Bhagwanjee S, Rubenfeld GD (2010) Critical care and the global burden of critical illness in adults. The Lancet 376:1339–1346

Google Scholar 

Aijaz N, Huda N, Kausar S (2013) Disease burden of NICU, at a tertiary care hospital, Karachi Journal of Dow University of Health Sciences

Alam MM, Saleem AF, Shaikh AS, Munir O, Qadir M (2014) Neonatal sepsis following prolonged rupture of membranes in a tertiary care hospital in Karachi Pakistan. J Infect Dev Count 8:067–073

Google Scholar 

Alemu M, Ayana M, Abiy H, Minuye B, Alebachew W, Endalamaw A (2019) Determinants of neonatal sepsis among neonates in the northwest part of Ethiopia: case-control study. Ital J Pediat 45:150

Google Scholar 

Alkema L, New JR, Pedersen J, You D (2014) Child mortality estimation 2013: an overview of updates in estimation methods by the United Nations Inter-agency Group for Child Mortality Estimation. PLoS ONE 9:e101112

PubMed  PubMed Central  Google Scholar 

Ayalew A, Abreha K, Shumey A, Berhane K (2015) Magnitude and predictors of early sexual debut among high and preparatory school students in northern Ethiopia: a school-based Crosssectional study. J Health Educ Res Dev, 1–8

Babiker W, Ahmed A, Babiker T, Ibrahim E, Almugadam B (2018) Prevalence and causes of neonatal sepsis in Soba University Hospital, Sudan. Med Microbiol Rep 1:11–13

Google Scholar 

Beletew B, Kassie A, Getu MA (2019a) Neonatal sepsis and its associated factors in East Africa: a systematic review and meta-analysis, 2019

Beletew B, Mengesha A, Wudu M, Abate M (2020) Prevalence of neonatal hypothermia and its associated factors in East Africa: a systematic review and meta-analysis. BMC Pediat 20:1–14

Google Scholar 

Beletew BA, Kasie AM, Kassaw MW, Reta MA (2019b) Neonatal hypothermia and its associated factors in East Africa: a systematic review and meta-analysis

Berkley JA et al (2005) Bacteremia among children admitted to a rural hospital in Kenya. N Engl J Med 352:39–47

CAS  PubMed  Google Scholar 

Chan GJ1 LA, Baqui AH, Tan J, Black RE. (2013) Risk of early-onset neonatal infection with maternal infection or colonization: a global systematic review and meta-analysis

Cizmeci MN, Kara S, Kanburoglu MK, Simavli S, Duvan CI, Tatli MM (2014) Detection of cord blood hepcidin levels as a biomarker for early-onset neonatal sepsis. Med Hypo 82:310–312

CAS  Google Scholar 

Debelew GT, Afework MF, Yalew AW (2014) Determinants and causes of neonatal mortality in Jimma zone, southwest Ethiopia: a multilevel analysis of prospective follow up study. PLoS ONE 9:e107184

PubMed  PubMed Central  Google Scholar 

Edmond K, Zaidi A (2010) New approaches to preventing, diagnosing, and treating neonatal sepsis. PLoS Med 7:e1000213

PubMed  PubMed Central  Google Scholar 

Egger M, Smith GD, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629–634

CAS  PubMed  PubMed Central  Google Scholar 

Emamghorashi F, Mahmoodi N, Tagarod Z, Heydari ST (2012) Maternal urinary tract infection as a risk factor for neonatal urinary tract infection, https://www.sid.ir/en/Journal/ViewPaper.aspx?ID=254881

Ethiopia Ministry Of Health (EMOH):(2015:1–182a) Health Sector Transformation Plan (HSTP 2015/16 - 2019/20 (2008–2012 EFY) October In.https://www.scholar.google.com/scholarhl=enas_sdt=0%2C5q=Ethiopia+Ministry+Of+Health+%28EMOH%29%3A+%282015%3A+1–2a%29+Health+Sector+Transformation+Plan%28HSTP+2015%2F16+-+2019%2F20+%282008–2012+EFY%29+October+In.%3BbtnG

Health Sector TransformationPlan (HSTP 2015/16 - 2019/20 (2008–2012 EFY) October In.; https://www.scholar.google.com/scholarhl=enas_sdt=0%2C5q=Ethiopia+Ministry+Of+Health+%28EMOH%29%3A+%282015%3A+1–182b%29+Health+Sector+Transformation+Plan%28HSTP+2015%2F16+-+2019%2F20+%282008–2012+EFY%29+October+In.%3B+btnG, 2015 Ethiopia Ministry Of Health (EMOH): (2015: 1–182b) Health Sector Transformation Plan (HSTP 2015/16 - 2019/20 (2008–2012 EFY) October In.; https://www.scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Ethiopia+Ministry+Of+Health+%28EMOH%29%3A+%282015%3A+1–182b%29+Health+Sector+Transformation+Plan%28HSTP+2015%2F16+-+2019%2F20+%282008–2012+EFY%29+October+In.%3B+&btnG

Fleischmann-Struzek C, Goldfarb DM, Schlattmann P, Schlapbach LJ, Reinhart K, Kissoon N (2018) The global burden of paediatric and neonatal sepsis: a systematic review. Lancet Respir Med 6:223–230

PubMed  Google Scholar 

Gebrehiwot A, Lakew W, Moges F, Anagaw B, Yismaw G, Unakal C (2012) Bacterial profile and drug susceptibility pattern of neonatal sepsis in Gondar University Hospital. Gondar Northwest Ethiopia Der Pharm Lett 4:1811–1816

CAS  Google Scholar 

Gebremedhin D, Berhe H, Gebrekirstos K (2016a) Risk factors for neonatal sepsis in public hospitals of Mekelle City, North Ethiopia, 2015: unmatched case control study. PloS one 11

Gebremedhin D, Berhe H, Gebrekirstos K (2016) Risk factors for neonatal sepsis in public hospitals of Mekelle City, North Ethiopia, 2015: unmatched case control study. PLoS ONE 11:e0154798

PubMed  PubMed Central  Google Scholar 

Getabelew A, Aman M, Fantaye E, Yeheyis T (2018) Prevalence of neonatal sepsis and associated factors among neonates in neonatal intensive care unit at selected governmental hospitals in Shashemene Town, Oromia Regional State, Ethiopia. In: 2017 international journal of pediatrics 2018

Grace J, Chan ACL, Abdullah H, Tan J, Black RE (2015) RESEARCH ARTICLE Open Access Prevalence of early-onset neonatal infection among newborns of mothers with bacterial infection or colonization: a systematic review and meta-analysis

Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539–1558

PubMed  Google Scholar 

Ioannidis JP (2008) Interpretation of tests of heterogeneity and bias in meta-analysis. J Eval Clin Pract 14:951–957

PubMed  Google Scholar 

Jabiri A, Wella HL, Semiono A, Saria A, Protas J (2016) Prevalence and factors associated with neonatal sepsis among neonates in Temeke and Mwananyamala Hospitals in Dar es Salaam, Tanzania. Tanzania J Health Res. 18

Jiang J-H et al (2004) Neonatal sepsis in the neonatal intensive care unit: characteristics of early versus late onset Journal of Microbiology. Immunol Infect 37:301–306

Google Scholar 

John BDM, Mathias L, Elizabeth N (2015) Risk factors and practices contributing to newborn sepsis in a rural district of Eastern Uganda, August 2013: a cross sectional study. BMC Res Notes 8:339

PubMed  PubMed Central  Google Scholar 

Kheir AE, Khair RA (2014) Neonatal sepsis; prevalence and outcome in a tertiary neonatal unit in Sudan. Time J Med Sci Rep Res 2:21–25

Google Scholar 

Kiwanuka J et al (2013) The microbial spectrum of neonatal sepsis in Uganda: recovery of culturable bacteria in mother-infant pairs. PLoS ONE 8:e72775

CAS  PubMed  PubMed Central  Google Scholar 

Laving A, Musoke R, Wasunna A, Revathi G (2003) Neonatal bacterial meningitis at the newborn unit of Kenyatta. Natl Hos East Afr Med J 80:456–462

CAS  Google Scholar 

Le Geyt J, Hauck S (2016) G272 Epidemiological trends of neonatal sepsis in a county referral hospital in central Kenya. BMJ Publishing Group Ltd

Leal YA, Álvarez-Nemegyei J, Velázquez JR, Rosado-Quiab U, Diego-Rodríguez N, Paz-Baeza E, Dávila-Velázquez J (2012) Risk factors and prognosis for neonatal sepsis in southeastern Mexico: analysis of a four-year historic cohort follow-up. BMC Pregnancy Childbirth 12:48

PubMed  PubMed Central  Google Scholar 

Liu L et al (2016) Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the Sustainable Development Goals. The Lancet 388:3027–3035

Google Scholar 

Markos Y, Dadi AF, Demisse AG, Ayanaw Habitu Y, Derseh BT, Debalkie G (2019) Determinants of under-five pneumonia at Gondar University Hospital, northwest Ethiopia: an unmatched case-control study. Journal of environmental and public health 2019

Mersha A et al (2019) Neonatal sepsis and associated factors among newborns in hospitals of Wolaita Sodo Town. Southern Ethiopia Res Rep Neonatol 9:1

Google Scholar 

Mobbs N et al (2019) Search of a primary outcome for community-based newborn infection trials in Eastern Uganda: a nested cohort study within the BabyGel pilot trial. Pilot Feasib Stud 5:43

CAS  Google Scholar 

Moges F, Eshetie S, Yeshitela B, Abate E (2017) Bacterial etiologic agents causing neonatal sepsis and associated risk factors in Gondar. Northwest Ethiopia BMC Pediatr 17:137

PubMed  Google Scholar 

Mugalu J, Nakakeeto M, Kiguli S, Kaddu-Mulindwa DH (2006) Aetiology, risk factors and immediate outcome of bacteriologically confirmed neonatal septicaemia in Mulago hospital. Uganda Afr Health Sci 6:120–126

CAS  PubMed  Google Scholar 

Naulikha JM, Orindi OT, Amollo AS, Obonyo CO (2018) Diagnosis and management of early-onset neonatal sepsis (Eos) among high-risk neonates in kisii teaching and referral hospital and Homabay county referral hospital, Western Kenya

Organization WH (2016) World health statistics 2016: monitoring health for the SDGs sustainable development goals. World Health Organization

Orwenyo GK (2011) maternal factors predisposing to early-onset neonatal sepsis at Kenyatta national hospital maternity unit. In: Ranjeva SL, Warf BC, Schiff SJ (2018) Economic burden of neonatal sepsis in sub-Saharan Africa BMJ global health 3:e000347

Rijal P, Shrestha M (2018) Analysis of Neonatal Respiratory Distress in Neonatal Intensive Care Unit at Nepal Medical College. J Nep Health Res Council 16:131–135

Google Scholar 

Santhanam S, Arun S, Rebekah G, Ponmudi NJ, Chandran J, Jose R, Jana AK (2017) Perinatal risk factors for neonatal early-onset group b streptococcal sepsis after initiation of risk-based maternal intrapartum antibiotic prophylaxis—a case control study. J Trop Pediat 64:312–316

Google Scholar 

Saugstad OD (2011) Reducing global neonatal mortality is possible. Neonatology 99:250–257

PubMed  Google Scholar 

Seale AC et al (2014) Estimates of possible severe bacterial infection in neonates in sub-Saharan Africa, south Asia, and Latin America for 2012: a systematic review and meta-analysis. Lancet Infect Dis 14:731–741

PubMed  PubMed Central  Google Scholar 

Seale AC, Mwaniki M, Newton CR, Berkley JA (2009) Maternal and early onset neonatal bacterial sepsis: burden and strategies for prevention in sub-Saharan Africa. Lancet Infect Dis 9:428–438

PubMed  PubMed Central  Google Scholar 

Shitaye D, Asrat D, Woldeamanuel Y, Worku B (2010) Risk factors and etiology of neonatal sepsis in Tikur Anbessa University Hospital. Ethiopia Ethiopian Med J 48:11–21

Google Scholar 

Shruti MurthyID MAG, Vasudeva Guddattu ID, Leslie Edward (2019) Risk factors of neonatal sepsis in India: A systematic review and meta-analysis

Murthy S, Godinho MA, Guddattu V, Lewis LES, Nair NS (2019) Risk factors of neonatal sepsis in India: a systematic review and meta-analysis. PloS one 14(4):e0215683

CAS  PubMed  PubMed Central  Google Scholar 

Siakwa M, Kpikpitse D, Mupepi SC, Semuatu M (2014) Neonatal sepsis in rural Ghana: A case control study of risk factors in a birth cohort

Simonsen KA, Anderson-Berry AL, Delair SF, Davies HD (2014) Early-onset neonatal sepsis. Clin Microbiol Rev 27:21–47

PubMed  PubMed Central  Google Scholar 

Soman M, Green B, Daling J (1985) Risk factors for early neonatal sepsis. Am J Epidemiol 121:712–719

CAS  PubMed  Google Scholar 

Talbert AW, Mwaniki M, Mwarumba S, Newton CR, Berkley JA (2010) Invasive bacterial infections in neonates and young infants born outside hospital admitted to a rural hospital in Kenya. Pediatr Infect Dis J 29:945

PubMed  PubMed Central  Google Scholar 

Tewabe T et al (2017) Clinical outcome and risk factors of neonatal sepsis among neonates in Felege Hiwot referral Hospital, Bahir Dar, Amhara Regional State, North West Ethiopia 2016: a retrospective chart review. BMC Res Notes 10:265

PubMed  PubMed Central  Google Scholar 

United Nations Children's Fund (UNICEF): (2014:1–100a) committing to Child Survival :A Promise Renewed World Health Organ Tech Rep Ser.

United Nations Children's Fund (UNICEF): (2014:1–100b) committing to Child Survival: A Promise Renewed World Health Organ Tech Rep Ser.

Wang ME, Patel AB, Hansen NI, Arlington L, Prakash A, Hibberd PL (2016) Risk factors for possible serious bacterial infection in a rural cohort of young infants in central India. BMC public health 16:1097

PubMed  PubMed Central  Google Scholar 

WHO U, (2014) Every newborn: an action plan to end preventable deaths. World Health Organization, Geneva

Google Scholar 

Woldu M, Guta M, Lenjisa J, Tegegne G, Tesafye G, Dinsa H (2014) Assessment of the incidence of neonatal sepsis, its risk factors, antimicrobial use and clinical outcomes in Bishoftu General Hospital Neonatal Intensive Care Unit. Debrezeit-Ethiopia Pediat Therapeut 4(2161–0665):1000214

Google Scholar 

Yancey MK, Duff P, Kubilis P, Clark P, Frentzen BH (1996) Risk factors for neonatal sepsis. Obstet Gynecol 87:188–194

CAS  PubMed  Google Scholar