Department of Infectious Diseases, Perth Children's Hospital, 15 Hospital Avenue, Nedlands WA 6009, Locked Bag 2010, Nedlands WA 6909, AUSTRALIAWesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, AUSTRALIANational Health and Medical Research Council, AUSTRALIADivision of Paediatrics, School of Medicine, University of Western Australia, AUSTRALIAMenzies School of Health Research, Charles Darwin University, AUSTRALIAInstitute for Health Research, The University of Notre Dame Australia