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The CRISPR tool kit for genome editing and beyond.

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The promise of single-cell RNA sequencing for kidney disease investigation.

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Conditional control of gene expression in the mouse.

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Rapid generation of inducible mouse mutants.

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Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells.

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Genetic lineage tracing with multiple DNA recombinases: A user’s guide for conducting more precise cell fate mapping studies.

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DNA recognition by the FLP recombinase of the yeast 2 μ plasmid.

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Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.

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Redefining the serotonergic system by genetic lineage.

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Split-Cre Complementation Indicates Coincident Activity of Different Genes In Vivo.

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A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting.

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A beginner’s guide to tissue clearing.

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Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny.

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Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.

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Tissue clearing and its applications in neuroscience.

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Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development.

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Single-cell mapping of lineage and identity in direct reprogramming.

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Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.

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Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding.

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Whole-organism lineage tracing by combinatorial and cumulative genome editing.

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Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain.

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An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells.

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Lineage tracing meets single-cell omics: opportunities and challenges.

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Synthetic recording and in situ readout of lineage information in single cells.

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In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription.

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Somatic mutation in single human neurons tracks developmental and transcriptional history.

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Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer.

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Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.

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Mechanisms of Renal Fibrosis.

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Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing.

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Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.

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Efficient Gene Transfer to Kidney Mesenchymal Cells Using a Synthetic Adeno-Associated Viral Vector.

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