Available online 26 July 2025, 102024

The question whether delaying genital surgery in individuals with differences/disorders of sex development is an option, or an even better option than early surgery, is complex and based on many considerations. The evidence must be considered poor for both alternatives. This review aims to evaluate some important outcome studies from the last two decades regarding the potential benefits of delayed genital surgery and explores the feasibility of performing male and female genitoplasty after the onset of puberty.

DSD

hypospadias

congenital adrenal hyperplasia

delayed genitoplasty

© 2025 The Author(s). Published by Elsevier Ltd.