The etiology of post-traumatic infections is multifactorial, influenced by the mechanism of injury, environmental exposure, and host immune status [1]. Agricultural machinery-related injuries pose unique challenges due to the high risk of contamination from diverse microbial ecosystems. Farm equipment, often contaminated with organic debris such as soil, crop residues, and animal excreta, can introduce a broad spectrum of microorganisms into open wounds [2]. This contamination significantly increases the risk of infection, particularly in severe trauma cases. These infections typically involve a complex mix of skin flora and environmental bacteria, complicating both diagnosis and treatment. Despite meticulous debridement and wound management, infections following agricultural injuries remain a significant concern.

Among these soil-associated pathogens, Pseudomonas spp. have long been recognized as significant causative organisms in post-traumatic infections, with P. aeruginosa being the most frequently encountered species in clinical practice [3]. While the pathogenic potential of common Pseudomonas spp. is well established, recent advances in bacterial identification techniques, particularly matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, have unveiled the clinical significance of previously underrecognized species within this genus. One such organism is Pseudomonas guariconensis, first isolated from rhizospheric soil in Venezuela in 2013, a gram-negative, strictly aerobic, non-spore-forming rod with polar flagella [4]. Of particular clinical concern is its frequent exhibition of multidrug resistance, including resistance to carbapenems, which significantly complicates therapeutic management [5]. Here, we present the first documented case of P. guariconensis-associated bacteremia and wound infection following an agricultural machinery injury in Japan. This case not only demonstrates the pathogenic potential of this emerging organism but also highlights the evolving complexity of post-traumatic infections in agricultural settings, emphasizing the need for enhanced surveillance and therapeutic strategies.