Albadari N, Deng S, Li W (2019) The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy. Expert Opin Drug Discov 14(7):667–682

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bocchicchio S, Tesone M, Irusta G (2019) Convergence of Wnt and Notch signaling controls ovarian cancer cell survival. J Cell Physiol 234(12):22130–22143

Article  CAS  PubMed  Google Scholar 

Cowman SJ, Fuja DG, Liu XD, Tidwell RSS, Kandula N, Sirohi D et al (2020) Macrophage HIF-1α is an independent prognostic indicator in kidney cancer. Clin Cancer Res 26(18):4970–4982

Article  CAS  PubMed  PubMed Central  Google Scholar 

De Francesco EM, Maggiolini M, Musti AM (2018) Crosstalk between Notch, HIF-1α and GPER in breast cancer EMT. Int J Mol Sci 19(7):2011

Article  PubMed  PubMed Central  Google Scholar 

Ding X, Huang R, Zhong Y, Cui N, Wang Y, Weng J et al (2020) CTHRC1 promotes gastric cancer metastasis via HIF-1α/CXCR4 signaling pathway. Biomed Pharmacother 123:109742

Article  CAS  PubMed  Google Scholar 

Duan R, Du W, Guo W (2020) EZH2: a novel target for cancer treatment. J Hematol Oncol 13(1):104

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elzakra N, Kim Y (2021) HIF-1α metabolic pathways in human cancer. Adv Exp Med Biol 1280:243–260

Article  CAS  PubMed  Google Scholar 

Farzaneh M, Kuchaki Z, Rashid Sheykhahmad F, Meybodi SM, Abbasi Y, Gholami E et al (2022) Emerging roles of JMJD3 in cancer. Clin Transl Oncol 24(7):1238–1249

Article  CAS  PubMed  Google Scholar 

Guenter R, Patel Z, Chen H (2021) Notch signaling in thyroid cancer. Adv Exp Med Biol 1287:155–168

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guo R, Yang B (2021) Hypoxia-induced LXRα contributes to the migration and invasion of gastric cancer cells. Folia Biol (Praha) 67(3):91–101

Article  CAS  PubMed  Google Scholar 

He C, Sun J, Liu C, Jiang Y, Hao Y (2019) Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin. Clin Epigenetics 11(1):8

Article  PubMed  PubMed Central  Google Scholar 

Huang Y, Zhang H, Wang L, Tang C, Qin X, Wu X et al (2020) JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency. Nat Commun 11(1):5061

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang J, Gou H, Yao J, Yi K, Jin Z, Matsuoka M et al (2021) The noncanonical role of EZH2 in cancer. Cancer Sci 112(4):1376–1382

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang Y, Pan W, Ma J (2024) SKP2-mediated ubiquitination and degradation of KLF11 promotes osteoarthritis via modulation of JMJD3/NOTCH1 pathway. FASEB J : Official Publ Fed Am Soc Exp Biol 38(9):e23640

Article  CAS  Google Scholar 

Ilango S, Paital B, Jayachandran P, Padma PR, Nirmaladevi R (2020) Epigenetic alterations in cancer. Front Biosci (Landmark Ed) 25(6):1058–1109

Article  CAS  PubMed  Google Scholar 

Inoue A, Jiang L, Lu F, Suzuki T, Zhang Y (2017) Maternal H3K27me3 controls DNA methylation-independent imprinting. Nature 547(7664):419–424

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jing X, Yang F, Shao C, Wei K, Xie M, Shen H et al (2019) Role of hypoxia in cancer therapy by regulating the tumor microenvironment. Mol Cancer 18(1):157

Article  PubMed  PubMed Central  Google Scholar 

Kawaguchi K, Kaneko S (2021) Notch signaling and liver cancer. Adv Exp Med Biol 1287:69–80

Article  CAS  PubMed  Google Scholar 

Lagunas-Rangel FA (2021) KDM6B (JMJD3) and its dual role in cancer. Biochimie 184:63–71

Article  CAS  PubMed  Google Scholar 

Li B, Han Y (2021) NSD1 stimulated survival and migration of gastric cancer cells through WNT10B. J Mens Health 17(3):139–144

Google Scholar 

Li H, Jia Y, Wang Y (2019) Targeting HIF-1α signaling pathway for gastric cancer treatment. Pharmazie 74(1):3–7

CAS  PubMed  Google Scholar 

Li HS, Zhou YN, Li L, Li SF, Long D, Chen XL et al (2019) HIF-1α protects against oxidative stress by directly targeting mitochondria. Redox Biol 25:101109

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lin MC, Lin JJ, Hsu CL, Juan HF, Lou PJ, Huang MC (2017) GATA3 interacts with and stabilizes HIF-1α to enhance cancer cell invasiveness. Oncogene 36(30):4243–4252

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Y, Wu J, Huang W, Weng S, Wang B, Chen Y et al (2020) Development and validation of a hypoxia-immune-based microenvironment gene signature for risk stratification in gastric cancer. J Transl Med 18(1):201

Article  CAS  PubMed  PubMed Central  Google Scholar 

Machlowska J, Baj J, Sitarz M, Maciejewski R, Sitarz R (2020) Gastric cancer: epidemiology, risk factors, classification, genomic characteristics and treatment strategies. Int J Mol Sci 21(11):4012

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matsuno K (2020) Notch signaling. Dev Growth Differ 62(1):3

Article  PubMed  Google Scholar 

Monticone G, Miele L (2021) Notch pathway: a journey from notching phenotypes to cancer immunotherapy. Adv Exp Med Biol 1287:201–222

Article  CAS  PubMed  Google Scholar 

Mu R, Zou YK, Tu K, Wang DB, Tang D, Yu Z et al (2021) Hypoxia promotes pancreatic cancer cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential by the HIF-1α/Notch signaling pathway. Pancreas 50(5):756–65

Article  CAS  PubMed  Google Scholar 

Pezzuto A, Carico E (2018) Role of HIF-1 in cancer progression: novel insights. A review. Curr Mol Med 18(6):343–351

Article  CAS  PubMed  Google Scholar 

Roy S, Huang B, Sinha N, Wang J, Sen A (2021) Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics. PLoS Genet 17(3):e1009483

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sanchez A, Houfaf Khoufaf FZ, Idrissou M, Penault-Llorca F, Bignon YJ, Guy L et al (2021) The Functions of the demethylase JMJD3 in cancer. Int J Mol Sci 22(2):968

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sebestyén A, Kopper L, Dankó T, Tímár J (2021) Hypoxia Signaling